15 completed, 5 terminated, 4 unknown, 3 not yet recruiting. 11 Phase 4, 7 Phase 2, 5 Phase 3, 3 Not applicable, 2 Phase 1.
Follow Luteinizing Hormone, beta Subunit: new trials by email Literature Review of Luteinizing Hormone, beta Subunit trials Research Report on Luteinizing Hormone, beta Subunit
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Extended LH Administration Recombinant LH (Luveris), No Treatment Added - Ovarian Reserve | Phase 2 | Not yet recruiting | Azienda Ospedaliero-Universitaria di Modena | 84 | 2025-03-17 | 2025-03-19 |
| Potential Benefit of r-hLH Addition in Patients Aged 35 to 40 Under Ovarian Stimulation Treatment Recombinant Human Follitropin Alfa Solution for Injection (Gonal-f®), Recombinant Human Lutropin alfa for Injection (r-hLH, Luveris®) - Infertility | Phase 4 | Not yet recruiting | Nanjing University | 300 | 2024-09-01 | 2024-08-27 |
| Extra Luteinizing Hormone Improve Embryo Quality in IVF Patients With Low LH During Long GnRH-Agonist Treatment Recombinant Luteinizing Hormone (rLH), Recombinant Follicle-Stimulating Hormone (rFSH), Gonadotropin-Releasing Hormone Agonist (GnRH-a) - Infertility, Female, Luteinizing Hormone (LH) | Not applicable | Recruiting | Nanjing University | 590 | 2024-02-01 | 2025-08-19 |
| FSH and LH Versus FSH Alone for Ovarian Stimulation in Non-hormone Sensitive Onco-fertility Patients Luveris - Fertility Preservation | Phase 3 | Not yet recruiting | Ellen Greenblatt | 140 | 2024-02-01 | 2024-01-29 |
| Effect of LH Supplementation on the Endometrial Gene Expression Profile in Poor Ovarian Responders Lutropin alfa, Follitropin alfa, Endometrial biopsy - Poor Response to Ovulation Induction | Phase 4 | Withdrawn | CRG UZ Brussel | 2023-05-01 | 2024-02-28 | |
| Rec-LH PD and Safety Profile in Hypogonadotropic Hypogonadism Men Lutropin alfa, Human chorionic gonadotropin - Acquired Hypogonadotropic Hypogonadism | Phase 2 | Unknown | Azienda Ospedaliero-Universitaria di Modena | 32 | 2022-01-19 | 2023-07-20 |
| Pergoveris FD and Liquid China BE Study Pergoveris FD, Pergoveris Liquid, Gonal-f - Healthy | Phase 1 | Completed | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany | 72 | 2021-05-08 | 2022-06-15 |
| Hormonal Mechanisms of Sleep Restriction - Axis Study in Older Men and Postmenopausal Women Ketoconazole Pill (also known as nizoral), Ganirelix, Dexamethasone Pill - Sleep Restriction | Early Phase 1 | Active not recruiting | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | 5 | 2020-02-09 | 2025-09-11 |
| An Observational Study of Follitropin Alpha Biosimilar: the Real-world Data Follitropin Alfa, Follicle Stimulating Hormone/Luteinizing Hormone - Reproductive Issues, Reproductive Disorder | Completed | IVFarma LLC | 5484 | 2020-01-12 | 2021-10-22 | |
| Recombinant LH Prior to Ovarian Stimulation in Poor Ovarian Responders (PRE-LH) Pre-treatment with rLH (Luveris 75 IU), - Infertility, Female | Phase 3 | Completed | Instituto Valenciano de Infertilidad, IVI Alicante | 88 | 2019-02-18 | 2024-10-09 |
| Corifollitropin Alfa Combined With Menotropin Versus Follitropin and Lutropin Alfa in Expected Suboptimal Responders Corifollitropin alfa and menotropin, Follitropin alfa and lutropin alfa - Infertility, Female | Phase 4 | Completed | D.O. Ott Research Institute of Obstetrics, Gynecology, and Reproductology | 32 | 2017-09-04 | 2019-09-12 |
| Hormonal Mechanisms of Sleep Restriction - Axis Study Ketoconazole Pill, Ganirelix, Dexamethasone - Sleep Restriction | Phase 1 | Active not recruiting | Peter y. Liu | 80 | 2017-05-08 | 2025-09-11 |
| Androgenic Profile Following Controlled Ovarian Stimulation recombinant gonadotropins, HP-HMG - Infertility, Female | Phase 4 | Unknown | Sheba Medical Center | 100 | 2016-12-01 | 2016-12-20 |
| Comparison of Assisted Reproductive Technology (ART) Outcomes Between Two Protocols of Induction of Ovulation in Patients With Hypogonadotropic Hypogonadism Lutropin alfa, Follitropin alfa and Lutropin alfa - Infertility | Phase 4 | Unknown | Royan Institute | 90 | 2012-11-01 | 2015-05-06 |
| A Trial to Compare the Efficacy and Safety of Ovarian Stimulation With GONAL-f® and Luveris® Starting on Day 1 Versus Day 6 in Women Undergoing Assisted Reproductive Technique GONAL-f®, Luveris®, Recombinant human chorionic gonadotropin (r-hCG) - Infertility, Fertility | Phase 3 | Terminated | Merck KGaA, Darmstadt, Germany | 174 | 2012-05-01 | 2015-11-09 |
| Reproductive Hormonal Alterations in Obesity Cetrorelix, Gonadorelin-GnRH, Recombinant LH - Obesity | Not applicable | Completed | University of Colorado, Denver | 62 | 2010-06-01 | 2017-01-12 |
| Severe LH Suppressed Patients After Administration of a GnRH Antagonist Recombinant LH (Luveris) - Infertility, Female Infertility, Male Infertility | Phase 4 | Completed | Assuta Hospital Systems | 50 | 2010-06-01 | 2013-09-05 |
| Ovarian Stimulation With Recombinant Gonadotropins vs. Human Menopausal Gonadotropin in In Vitro Fertilization rFSH plus rLH, hMG - Infertility | Completed | University of Turin, Italy | 848 | 2010-03-01 | 2014-12-23 | |
| To Describe the Effect of rhLH Supplementation in Women With Hyporesponse to rhFSH After Pituitary Downregulation Luveris - Infertility | Phase 2 | Unknown | Peking University Third Hospital | 150 | 2009-12-01 | 2009-12-10 |
| The Luveris In Vitro Fertilization Trial Luveris fixed dose, Luveris increasing dose - Infertility, Hypothalamic Amenorrhea | Phase 4 | Terminated | University Reproductive Associates | 14 | 2009-04-01 | 2018-08-07 |
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Infertility (16) · Helping Behavior (5) · Infertility, Female (5) · Hypogonadism (3) · Infertility, Male (2) · Genital Diseases, Female (1) · Hyperprolactinemia (1) · Obesity (1)
Merck KGaA, Darmstadt, Germany (6) · Azienda Ospedaliero-Universitaria di Modena (2) · EMD Serono (2) · Nanjing University (2) · Assuta Hospital Systems (1) · CRG UZ Brussel (1) · Copenhagen University Hospital, Rigshospitalet (1) · D.O. Ott Research Institute of Obstetrics, Gynecology, and Reproductology (1) · Ellen Greenblatt (1) · IVFarma LLC (1) · Instituto Valenciano de Infertilidad, IVI Alicante (1) · Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (1) · Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany (1) · Peking University Third Hospital (1) · Peter y. Liu (1)
United States (6) · China (5) · Spain (5) · Italy (2) · Russia (2) · Canada (1) · Denmark (1) · Iran (1) · Israel (1) · United Arab Emirates (1)
Peter Liu, MD, PhD (2) · Alberto Revelli, MD PhD (1) · Alexdandr Gzgzyan, Prof, PhD (1) · Allison M Case, MD FRCSC (1) · Anders N Andersen, professor (1) · Angela R Baerwald, PhD (1) · Antonio La Marca, MD, PhD (1) · Christophe Blockeel (1) · Dilorom Kamilova, PhD (1) · Ellen Greenblatt, MD FRCSC (1) · Haiming Xia, Dr. (1) · Hamid Gourabi, PhD (1) · Jie Qiao, MD, PhD (1)
PMID 18024487, PMID 20031032, PMID 21575849, PMID 22819187, PMID 23958434, PMID 25452708, PMID 34937512, PMID 36107111
2005 (1), 2008 (1), 2017 (1), U54HD058155 (1)