5 completed, 1 recruiting, 1 terminated, 1 withdrawn. 3 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 2, Withdrawn 1 |
| Phase 2 | 2 | Terminated 1, Withdrawn 1 |
Follow Herpes Simplex Virus: new trials by email Literature Review of Herpes Simplex Virus trials Research Report on Herpes Simplex Virus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Quantification & Classification of Inflammatory Cells in Uveitis Using OCT Anterior Uveitis (AU), Birdshot Chorioretinitis | Recruiting | Oregon Health and Science University | 125 | 2024-09-01 | 2025-07-17 | |
| Phase I Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single Doses of IM-250 in Healthy Volunteers IM-250 (50 mg), IM-250 (100 mg), IM-250 (200 mg) - Herpes Simplex Virus | Phase 1 | Completed | Innovative Molecules GmbH | 18 | 2023-04-25 | 2024-10-24 |
| A Safety and Dose-Determining Study of CMX001 In Infants With Neonatal Herpes Simplex Virus (HSV) Infection Involving the Central Nervous System (CNS Disease) Novel Antiviral Drug, Placebo - Herpes Simplex Virus | Phase 1 / Phase 2 | Withdrawn | University of Alabama at Birmingham | 2016-01-01 | 2016-06-07 | |
| Review of Human Herpes Viruses in Burns Review of the Literature for Human Herpes Virus infections - Human Herpes Virus, Herpes Simplex Virus | Completed | The University of Texas Medical Branch, Galveston | 10267 | 2015-03-01 | 2015-05-22 | |
| Identification of Herpes Simplex Virus (HSV) Shedding in the Female Genital Tract of Pregnant and Nonpregnant Women by GeneXpert PCR, Routine PCR, and Culture Genexpert assay - Herpes Simplex Virus | Completed | University of Alabama at Birmingham | 12550 | 2014-01-01 | 2020-09-09 | |
| Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care: - Adenovirus, Anesthesia | Completed | Daniel Benjamin | 3520 | 2011-11-01 | 2023-09-06 | |
| A Study to Describe the Pharmacokinetics of Acyclovir in Premature Infants (PTN_Acyclo) Acyclovir - Herpes Simplex Virus, Neonatal Sepsis | Phase 1 | Completed | Phillip Brian Smith | 32 | 2011-09-01 | 2019-01-08 |
| A Randomized Double-Blind Control-Comparison Crossover Trial of Oral Glutamine to Suppress Frequently Recurrent Herpes Labialis Glutamine, Glycine - Herpes Labialis, Herpes Simplex Virus | Phase 2 | Terminated | National Institute of Allergy and Infectious Diseases (NIAID) | 11 | 2009-06-01 | 2012-06-11 |
Herpes Simplex (8) · Sepsis (2) · Adenoviridae Infections (1) · Anxiety Disorders (1) · Arrhythmias, Cardiac (1) · Arthritis, Juvenile (1) · Autistic Disorder (1) · Behcet Syndrome (1) · Bipolar Disorder (1) · Birdshot Chorioretinopathy (1) · Bradycardia (1) · Burns (1) · Central Nervous System Infections (1) · Chickenpox (1) · Cytomegalovirus Retinitis (1)
DNA Virus Infections (8) · Herpesviridae Infections (8) · Skin Diseases (8) · Skin Diseases, Infectious (8) · Skin Diseases, Viral (8) · Skin and Connective Tissue Diseases (8) · Virus Diseases (8) · Infections (7) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Cardiovascular Diseases (2) · Eye Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Genetic Diseases, Inborn (2) · Hemic and Lymphatic Diseases (2) · Mouth Diseases (2)
Acyclovir (1) · Alfentanil (1) · Amikacin (1) · Aminocaproic Acid (1) · Bosentan (1) · Cefepime (1) · Cidofovir (1) · Ciprofloxacin (1) · Clozapine (1) · Fosfomycin (1) · Glutamine (1) · Glycine (1) · Haloperidol (1) · Labetalol (1) · Lurasidone Hydrochloride (1)
University of Alabama at Birmingham (2) · Daniel Benjamin (1) · Innovative Molecules GmbH (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Oregon Health and Science University (1) · Phillip Brian Smith (1) · The University of Texas Medical Branch, Galveston (1)
United States (6) · Canada (1) · Germany (1) · Israel (1) · Singapore (1) · United Kingdom (1)
David W Kimberlin, MD (2) · Richard Whitley, MD (2) · Chi Hornik, PharmD (1) · David N Herndon, MD, FACS (1) · Phillip B Smith, M.D. (1) · Yan Li, PhD (1)
PMID 18846389, PMID 24614374, PMID 24949994, PMID 26039810, PMID 26926644, PMID 27522443, PMID 28137820, PMID 28290120, PMID 28779462, PMID 29084742, PMID 29271816, PMID 29435949, PMID 29677389, PMID 30790601, PMID 31317556, PMID 31548185, PMID 31814149, PMID 32324313, PMID 32497307, PMID 33029806, PMID 33903114, PMID 34302290, PMID 35370711, PMID 35491971, PMID 41247430
R21EY036563 (1)