10 completed, 7 not yet recruiting, 6 recruiting, 1 withdrawn. 14 Not applicable, 2 Phase 1, 2 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 14 | Completed 7, Not yet recruiting 5, Recruiting 2 |
| Phase 1 | 2 | Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 2 | Not yet recruiting 1, Recruiting 1 |
| Phase 4 | 1 | Recruiting 1 |
Follow Hemodynamic Changes: new trials by email Literature Review of Hemodynamic Changes trials Research Report on Hemodynamic Changes
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Influence of Lung Volume Optimization Maneuver on Cardiac Output and Lung Compliance in Ventilated Children With Congenital Heart Disease Undergoing Surgical Repair End-expiratory lung volume optimization maneuver with PEEP titration, Standard Care (in control arm) - Congenital Heart Disease, Cardiopulmonary Bypass | Phase 1 / Phase 2 | Not yet recruiting | Charite University, Berlin, Germany | 80 | 2027-01-01 | 2026-10-15 |
| Assessment of Total Pulmonary Resistance sPAP/CO Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH Descent from 2850m to sea level - Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 20 | 2026-09-25 | 2026-09-04 |
| Assessment of Total Pulmonary Resistance sPAP/CO Between Sea Level LA vs. High Altitude HA After Re-ascent in Healthy Individuals Re-Ascent from sea level to 2850m - High Altitude, Healthy | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 14 | 2026-09-25 | 2026-09-04 |
| Assessment of Total Pulmonary Resistance sPAP/CO Between High Altitude HA vs. Sea Level LA in Healthy Individuals H Descent from 2850m to sea level - High Altitude, Healthy Adult | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 14 | 2026-09-25 | 2026-09-04 |
| Hemodynamic Effects of Bilateral and Unilateral Spinal Anesthesia Using the Continuous Pressure Recording Analytical Method. Unilateral Spinal Anesthesia, Bilateral Spinal Anesthesia - Spinal Anesthesia, Hemodynamic Changes | Not applicable | Recruiting | Kayseri City Hospital | 74 | 2026-05-01 | 2026-08-27 |
| Right Ventricular Function and Respiratory Acidosis After Cardiac Surgery Not applicable- observational study - Respiratory Acidosis in ICU Patients, Right Ventricular (RV) Dysfunction | Not yet recruiting | Laval University | 220 | 2026-05-01 | 2026-06-01 | |
| Effect of Nalbuphine Versus Fentanyl on Hemdoynamic Effects of Laryngoscopy Nalbuphine, Fentanyl - Laryngoscopy, Hemodynamic Changes | Phase 4 | Recruiting | Rawalpindi Institute of Cardiology | 98 | 2026-02-21 | 2026-02-27 |
| IVC Collapsibility Index in Lumbar Stabilization Surgery Lumbar Spine Surgery, Hemodynamic Changes | Recruiting | Trabzon Kanuni Education and Research Hospital | 128 | 2026-02-15 | 2026-04-23 | |
| Effect of Patient Position on Bupivacaine Dose Requirement and Hemodynamic Stability in Spinal Anesthesia Bupivacaine %0.5 (hyperbaric) - Spinal Anesthesia, Hemodynamic Changes | Not applicable | Not yet recruiting | University of Health Sciences Balikesir Hospital Eduation and Research | 100 | 2026-01-30 | 2026-01-29 |
| Passive Leg Raising in Term Pregnancy on Hemodynamic Monitoring - Validating With Transthoracic ECHO (LG-ECHO) ClearSight™ System, Transthoracic Echocardiography, Passive Leg Raising (PLR) Maneuver - Maternity, Pregnancy | Withdrawn | Ayse Zeynep Turan Civraz | 2026-01-01 | 2026-01-29 | ||
| Influence of Personalized Lung Volume Optimization Maneuver on Lung Function and Cardiac Performance in Children End-expiratory lung volume optimization maneuver with PEEP titration, Standard Care (in control arm) - Congenital Heart Disease, Cardiopulmonary Bypass | Phase 1 / Phase 2 | Recruiting | Charite University, Berlin, Germany | 80 | 2025-12-05 | 2026-10-15 |
| Effect of Stress Ball During Chest Tube Removal After Open Heart Surgery Stress ball - Pain, Hemodynamic Changes | Not applicable | Completed | Mersin University | 66 | 2025-11-27 | 2026-08-12 |
| Dexmedetomidine and Propofol for Sedation in Cataract Surgery. Dexmedetomidine (DEX), Propofol (PRO), Fentanyl (FEN) - Sedation, Cataract | Not applicable | Recruiting | Saint-Joseph University | 1000 | 2025-11-09 | 2026-04-29 |
| Association Between Lingual Retraction and Hemodynamic Changes in Patients Receiving Dental Treatment Under General Anesthesia Trigeminocardiac Reflex, Hemodynamic Changes | Completed | Kırıkkale University | 85 | 2025-10-13 | 2026-04-09 | |
| Effects of Music Therapy on Anesthetic Requirements and Hemodynamic Parameters music therapy during surgery - Hemodynamic Changes, Music Therapy | Completed | Cukurova University | 159 | 2025-10-01 | 2026-02-17 | |
| Efficacy of Nebulized Dexmedetomidine on Blunting Hemodynamic Changes During Intubation and Pneumoperitoneum in Morbid Obese Patients During Laparoscopic Bariatric Surgery Dexmedetomidine, Normal Saline - Nebulization, Dexmedetomidine | Not applicable | Completed | Tanta University | 90 | 2025-07-10 | 2025-12-23 |
| Cerebral Regional Oxygen Saturation During TAVI - The CROS-TAVI Prospective Registry Near-infrared spectroscopy monitoring (NIRS) INVOS 5100C - Aortic Stenosis Disease, TAVI(Transcatheter Aortic Valve Implantation) | Not applicable | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 40 | 2025-06-01 | 2025-06-26 |
| Study of Cardiac Power Index During Supine, Lateral, and Between Left and Right Positions During Two- and One-Lung Ventilation (OLV): Comparison of Hemodynamic Changes After Lung Recruitment Maneuver and Fluid Challenge Among Responders and Non-Responders (SVI, MAP, CPI Changes). Fluid challenge during one-lung ventilation (OLV) in the lateral decubitus position, Hemodynamic monitoring - Thoracic Surgical Procedures, One-lung Ventilation (OLV) | Not applicable | Completed | Maria Fountoulaki | 70 | 2025-05-06 | 2026-10-27 |
| Assessment of Venous Return During Volume Expansion: a Prospective Observational Study Fluid challenge of 500ml of crystalloid - Hemodynamic Changes | Recruiting | Università Politecnica delle Marche | 45 | 2025-03-01 | 2026-03-30 | |
| Comparison of Computer-Assisted and Conventional Local Anesthesia Methods in Mandibular Impacted Third Molar Surgery Computer-Assisted Local Anesthesia, Conventional Local Anesthesia - Molar, Third, Surgery, Oral | Not applicable | Completed | Afyonkarahisar Health Sciences University | 40 | 2025-03-01 | 2025-12-10 |
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Altitude Sickness (3) · Hypoxia (3) · Anxiety Disorders (2) · Heart Defects, Congenital (2) · Aortic Valve Stenosis (1) · Body Weight Changes (1) · Bradycardia (1) · Cataract (1) · Fractures, Stress (1) · Glossoptosis (1) · Hypertension, Pulmonary (1) · Motor Activity (1) · Nausea (1) · Obesity, Morbid (1) · Pain (1)
Pathological Conditions, Signs and Symptoms (7) · Signs and Symptoms (7) · Cardiovascular Diseases (5) · Heart Diseases (4) · Respiration Disorders (3) · Respiratory Tract Diseases (3) · Signs and Symptoms, Respiratory (3) · Body Weight (2) · Cardiovascular Abnormalities (2) · Congenital Abnormalities (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Mental Disorders (2) · Aortic Valve Disease (1) · Arrhythmias, Cardiac (1) · Behavior (1)
Dexmedetomidine (2) · Fentanyl (2) · Standard of Care (2) · Anesthesia, General (1) · Crystalloid Solutions (1) · Echocardiography (1) · Hemodynamic Monitoring (1) · Muscle Stretching Exercises (1) · Nalbuphine (1) · Propofol (1) · Saline Solution (1) · Spectroscopy, Near-Infrared (1)
Silvia Ulrich Somaini (3) · Charite University, Berlin, Germany (2) · Tanta University (2) · Afyonkarahisar Health Sciences University (1) · Ali Kamil GÜNGÖR (1) · Ataturk University (1) · Ayse Zeynep Turan Civraz (1) · Cukurova University (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Kayseri City Hospital (1) · Kırıkkale University (1) · Laval University (1) · Maria Fountoulaki (1) · Mersin University (1) · Rawalpindi Institute of Cardiology (1)
Turkey (Türkiye) (8) · Switzerland (3) · Egypt (2) · Germany (2) · Italy (2) · United States (2) · Canada (1) · Greece (1) · Lebanon (1) · Pakistan (1)
Rodrigo Hoyos (3) · Silvia Ulrich (3) · Ayten Saracoglu, Prof. MD (1) · Cristina Aurigemma (1) · Mediha Turktan, M.D. (1) · Naji Abou Jalad, MD (1) · Qudsia Qureshi, MBBS (1)
PMID 15699287, PMID 21373870, PMID 23588488, PMID 26642915, PMID 29705484, PMID 32566379, PMID 37754676, PMID 41787568, PMID 42556464, PMID 8598068