10 completed, 2 terminated, 1 unknown. 13 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 13 | Completed 10, Terminated 2, Unknown 1 |
| Phase 2 | 1 | Terminated 1 |
Follow Hemangiosarcoma: new trials by email Literature Review of Hemangiosarcoma trials Research Report on Hemangiosarcoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Trial of TRC105 and Pazopanib Versus Pazopanib Alone in Patients With Advanced Angiosarcoma TRC105, Votrient - Advanced Angiosarcoma | Phase 3 | Completed | Tracon Pharmaceuticals Inc. | 128 | 2017-02-13 | 2020-05-12 |
| Doxorubicin Hydrochloride or Trabectedin in Treating Patients With Previously Untreated Advanced or Metastatic Soft Tissue Sarcoma doxorubicin hydrochloride, trabectedin, laboratory biomarker analysis - Sarcoma | Phase 2 / Phase 3 | Terminated | European Organisation for Research and Treatment of Cancer - EORTC | 133 | 2011-05-01 | 2014-08-08 |
| Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer cyproheptadine hydrochloride, placebo - Cancer | Phase 3 | Terminated | University of South Florida | 22 | 2010-06-01 | 2015-07-02 |
| Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma doxorubicin hydrochloride, clinical observation, therapeutic conventional surgery - Adult Alveolar Soft-part Sarcoma, Adult Angiosarcoma | Phase 3 | Completed | Children's Oncology Group | 588 | 2007-02-05 | 2022-04-28 |
| Randomised Trial of Volume of Post-operative Radiotherapy Given to Adult Patients With eXtremity Soft Tissue Sarcoma radiotherapy - Sarcoma | Phase 3 | Completed | Sheffield Teaching Hospitals NHS Foundation Trust | 216 | 2006-03-01 | 2021-03-18 |
| Ifosfamide and Doxorubicin, Radiation Therapy, and/or Surgery in Treating Young Patients With Localized Soft Tissue Sarcoma doxorubicin hydrochloride, ifosfamide, adjuvant therapy - Childhood Malignant Fibrous Histiocytoma of Bone, Sarcoma | Phase 3 | Unknown | European Paediatric Soft Tissue Sarcoma Study Group | 250 | 2006-03-01 | 2013-08-12 |
| Surgery With or Without Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Retroperitoneum or Pelvis conventional surgery, radiation therapy - Sarcoma | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 370 | 2004-08-01 | 2016-07-06 |
| Doxorubicin With or Without Ifosfamide and Pegfilgrastim in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma pegfilgrastim, doxorubicin hydrochloride, ifosfamide - Sarcoma | Phase 3 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 455 | 2003-04-01 | 2014-10-27 |
| Ifosfamide or Doxorubicin in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma doxorubicin hydrochloride, ifosfamide - Sarcoma | Phase 3 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 780 | 1998-01-01 | 2012-01-20 |
| Combination Chemotherapy With or Without Hyperthermia Therapy in Treating Patients With Soft Tissue Sarcoma doxorubicin hydrochloride, etoposide, ifosfamide - Sarcoma | Phase 3 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 340 | 1997-07-01 | 2013-09-17 |
| Surgery With or Without Combination Chemotherapy in Treating Patients With Lung Metastases From Soft Tissue Sarcoma filgrastim, doxorubicin hydrochloride, ifosfamide - Endometrial Cancer, Kidney Cancer | Phase 3 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 340 | 1996-04-01 | 2012-07-11 |
| Surgery With or Without Chemotherapy in Treating Patients With Soft Tissue Sarcoma filgrastim, doxorubicin hydrochloride, ifosfamide - Endometrial Cancer, Kidney Cancer | Phase 3 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 350 | 1995-02-01 | 2014-08-08 |
| Surgery Followed by Chemotherapy in Treating Young Patients With Soft Tissue Sarcoma dactinomycin, carboplatin, cyclophosphamide - Childhood Malignant Fibrous Histiocytoma of Bone, Sarcoma | Phase 3 | Completed | Societe Internationale d'Oncologie Pediatrique | 400 | 1995-01-01 | 2013-12-04 |
Fibrosarcoma (12) · Sarcoma (12) · Liposarcoma (11) · Histiocytoma, Malignant Fibrous (9) · Leiomyosarcoma (9) · Neurofibrosarcoma (9) · Sarcoma, Synovial (9) · Hemangiopericytoma, Malignant (8) · Malignant mesenchymal tumor (6) · Sarcoma, Alveolar Soft Part (5) · Rhabdomyosarcoma (4) · Chondrosarcoma, Extraskeletal Myxoid (3) · Sarcoma, Endometrial Stromal (3) · Chondrosarcoma (2)
Neoplasms by Histologic Type (13) · Neoplasms, Connective and Soft Tissue (13) · Neoplasms, Vascular Tissue (13) · Neoplasms (12) · Neoplasms, Connective Tissue (12) · Neoplasms, Fibrous Tissue (12) · Neoplasms, Adipose Tissue (11) · Neoplasms, Nerve Tissue (11) · Nervous System Diseases (10) · Nervous System Neoplasms (10) · Peripheral Nervous System Neoplasms (10) · Histiocytoma (9) · Neoplasms, Muscle Tissue (9) · Nerve Sheath Neoplasms (9) · Neurofibroma (9)
Doxorubicin (8) · Ifosfamide (8) · Radiotherapy (6) · Chemotherapy, Adjuvant (3) · Etoposide (2) · Filgrastim (2) · Neoadjuvant Therapy (2) · Brachytherapy (1) · Carboplatin (1) · Combined Modality Therapy (1) · Cyclophosphamide (1) · Cyproheptadine (1) · Dactinomycin (1) · Diathermy (1) · Epirubicin (1)
European Organisation for Research and Treatment of Cancer - EORTC (6) · Alliance for Clinical Trials in Oncology (1) · Children's Oncology Group (1) · European Paediatric Soft Tissue Sarcoma Study Group (1) · Sheffield Teaching Hospitals NHS Foundation Trust (1) · Societe Internationale d'Oncologie Pediatrique (1) · Tracon Pharmaceuticals Inc. (1) · University of South Florida (1)
United Kingdom (8) · France (6) · Germany (6) · Spain (6) · Austria (5) · Belgium (5) · Denmark (5) · United States (5) · Canada (4) · Netherlands (4) · Slovakia (4) · Switzerland (4) · Poland (3) · Hungary (2) · Italy (2)
A.N. Van Geel, MD (1) · Andrea Ferrari, MD (1) · Bernadette Brennan, MD (1) · Charles Theuer, MD (1) · Ian R. Judson, MA, MD, FRCP (1) · James E. Butrynski, MD (1) · Jeffrey P. Krischer, PhD (1) · Joern Treuner, MD (1) · Laurence H. Baker, DO, FACOI (1) · M. C. G. Stevens, MD (1) · Martin Robinson, MD (1) · Max Van Noesel, MD, PhD (1) · Modesto Carli, MD (1) · Nguyen Binh Bui, MD (1) · Paul C. Lorigan, MD (1)
PMID 17634494, PMID 20434400, PMID 22665534, PMID 22954508, PMID 24618336, PMID 24747207, PMID 28391003, PMID 29450452, PMID 30357394, PMID 30954717, PMID 31786124, PMID 33548339, PMID 34623899, PMID 34666214, PMID 35357396, PMID 36566574, PMID 38757485, PMID 39122389, PMID 41386267, PMID 42035475
2009 (1), U10CA081920 (1), U10CA098543 (1)