10 recruiting, 6 not yet recruiting, 5 completed, 2 enrolling by invitation. 18 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 18 | Not yet recruiting 6, Recruiting 6, Completed 3, Enrolling by invitation 2, Active not recruiting 1 |
Follow Heart Rate Variability (HRV): new trials by email Literature Review of Heart Rate Variability (HRV) trials Research Report on Heart Rate Variability (HRV)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Assessment of Heart Rate Variability HRV During Descent DE From 2850m to Sea Level and During Re-ascent A From Sea Level to 2850m in Healthy Individuals H Descent and re-ascent (2850m, sea level) - Healthy, Healthy Adult | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 14 | 2026-09-25 | 2026-09-03 |
| Assessment of Heart Rate Variability HRV During Descent DE From 2850m to Sea Level and During Re-ascent A From Sea Level to 2850m in Patients With Pulmonary Arterial Hypertension PAH Descent and re-ascent (2850m, sea level) - High Altitude Effects, High Altitude | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 20 | 2026-09-25 | 2026-09-03 |
| Heart Rate Variability Changes and Postoperative Delirium After Major Abdominal Surgery Perioperative Heart Rate Variability Changes - Postoperative Delirium (POD), Heart Rate Variability (HRV) | Recruiting | The First Affiliated Hospital with Nanjing Medical University | 500 | 2026-09-21 | 2026-09-28 | |
| Heart Rate Variability for Practitioner Stimulated Reflection and Decision-making Optimisation Critical Participatory Action Intervention with HRV Feedback - Critical Care Nursing, Decision Making | Not applicable | Recruiting | Papworth Hospital NHS Foundation Trust | 20 | 2026-07-14 | 2026-09-18 |
| Examining Relationships Between Musculoskeletal Function Measurements of Movement Efficiency and Nervous System Function After Chronic Stroke Stroke, Osteopathic Medicine | Recruiting | University of California, Davis | 100 | 2026-07-01 | 2026-07-30 | |
| Evolution of Hypoxic Burden and Sympathetic/Parasympathetic Balance in Patients With Pulmonary Hypertension Standard Clinical and Functional Assessment, Overnight Polysomnography - Precapillary Pulmonary Hypertension, Pulmonary Arterial Hypertension | Not applicable | Not yet recruiting | University Hospital, Rouen | 60 | 2026-06-01 | 2026-04-15 |
| Functional and Physiological Responses to Multicomponent Exercise in Older Adults Multicomponent Exercise Program - Older Adults (60 - 85 Years Old), Aging | Not applicable | Active not recruiting | Çanakkale Onsekiz Mart University | 40 | 2026-06-01 | 2026-08-04 |
| Heart Rate VAriability as a MaRker for tItrATing hIgh flOw Nasal Cannula Therapy Respiratory Failure, Heart Rate Variability (HRV) | Recruiting | University Health Network, Toronto | 20 | 2026-05-26 | 2026-06-18 | |
| Mobile Dual-Task Brain and Balance Intervention for Concussion Recovery Home-Based Mobile Dual-Task Intervention (BraW-Day™) - Mild Traumatic Brain Injury (mTBI), Sports-related Concussion | Not applicable | Not yet recruiting | Hyunhwa Lee | 20 | 2026-05-15 | 2026-05-20 |
| Anxiety and Physiological Responses in Ambulatory Surgery Self-selected Music intervention, Fixed-music Music intervention - Anxiety, Heart Rate Variability (HRV) | Not applicable | Not yet recruiting | Da-Yeh University | 90 | 2026-02-23 | 2026-03-17 |
| Effects of Controlled Breathing on Cardiorespiratory Variables in Multiple Myeloma Controlled breathing exercise protocol + therapeutic exercise + initial education session, Therapeutic exercise + initial education session - Multiple Myeloma (MM), Breathing Techniques | Not applicable | Recruiting | Universidad Complutense de Madrid | 26 | 2026-02-11 | 2026-10-01 |
| Heart Rate Variability and Anxiety as Predictors of Emergence Agitation After Septorhinoplasty Emergence Agitation, Heart Rate Variability (HRV) | Recruiting | Konya City Hospital | 100 | 2026-02-01 | 2026-08-20 | |
| Efficacy of Transcutaneous Auricular Vagus Nerve Stimulation on Alleviating Major Depressive Disorder in Patients With Acute Coronary Syndrome After Percutaneous Coronary Intervention:A Prospective, Double-Blind,Randomized Controlled Study Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) Intervention, sham Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) Control - Depressive Disorder (Per DSM-V Criteria, Mild-to-moderate), Acute Coronary Syndrome (ACS) | Not applicable | Recruiting | Jing Han | 120 | 2026-01-06 | 2026-06-16 |
| App-based Breathing Program for Migraine Relief Baseline Survey, Heart rate variability biofeedback, Sham Control Group - Migraine, Heart Rate Variability (HRV) | Not applicable | Enrolling by invitation | Arizona State University | 30 | 2025-12-15 | 2026-07-23 |
| Evaluating the Feasibility, Acceptability, and Preliminary Outcomes of Heart Rate Variability Biofeedback for Individuals With Opioid Use Disorder. Heart rate variability biofeedback - Autonomic Nervous System Imbalance, Heart Rate Variability (HRV) | Not applicable | Completed | Arizona State University | 32 | 2025-12-01 | 2026-05-15 |
| Effects of Magnesium L-Threonate on Sleep, Recovery, and Athletic Performance in Collegiate Athletes Magnesium L-Threonate, Placebo - Recovery of Function (G11.427.698.620), Athletic Performance | Not applicable | Completed | University of California, Los Angeles | 109 | 2025-10-01 | 2026-10-20 |
| Where Wild Things Grow: Nature- and Activity-based Group Interventions for Neurodivergent Children and Youth Universal approach, Selective approach, Outdoor therapy - Neurodevelopmental Outcomes, ADHD - Attention Deficit Disorder With Hyperactivity | Not applicable | Recruiting | Sorlandet Hospital HF | 240 | 2025-09-01 | 2025-10-02 |
| Effects os Physiotherapeutic Rehabilitation on Function Autonomic and Inflammatory in Patients With Long Covid physiothreapy protocol - Long COVID, Heart Rate Variability (HRV) | Not applicable | Not yet recruiting | Universidade do Estado do Pará | 58 | 2025-08-11 | 2025-07-01 |
| Correlation Between the R-R Interval of the Electrocardiogram and the Intracranial Pulse Wave Interval Assessed by a Noninvasive Method in Healthy People Evaluate the correlation between R-R interval and R-R equivalent on the noninvasive intracranial compliance monitor (BRV) and evaluate their correspondence considering the Time domain (HR, NN, NN50, R - Heart Rate Variability (HRV), Intracranial Pressure Change | Completed | Federal University of São Paulo | 103 | 2025-06-01 | 2026-06-01 | |
| Predictive Role of HRV for PONV in Laparoscopic Cholecystectomy Postoperative Nausea and Vomiting (PONV), Heart Rate Variability (HRV) | Completed | Konya City Hospital | 110 | 2025-05-02 | 2025-09-16 |
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Altitude Sickness (2) · Anxiety Disorders (2) · Emergence Delirium (2) · Pulmonary Arterial Hypertension (2) · Respiratory Aspiration (2) · Acute Coronary Syndrome (1) · Arrhythmias, Cardiac (1) · Attention Deficit Disorder with Hyperactivity (1) · Autistic Disorder (1) · Brain Concussion (1) · Chronic Pain (1) · Depression (1) · Depressive Disorder (1) · Emotional Regulation (1) · Headache (1)
Mental Disorders (8) · Nervous System Diseases (8) · Pathologic Processes (7) · Pathological Conditions, Signs and Symptoms (7) · Respiratory Tract Diseases (7) · Cardiovascular Diseases (6) · Respiration Disorders (6) · Signs and Symptoms (5) · Brain Diseases (4) · Central Nervous System Diseases (4) · Vascular Diseases (4) · Behavior (3) · Heart Diseases (3) · Lung Diseases (3) · Neurologic Manifestations (3)
Built Environment (1) · Dietary Supplements (1) · Exercise Therapy (1) · Methods (1) · Surveys and Questionnaires (1) · threonic acid (1)
Arizona State University (2) · Konya City Hospital (2) · Silvia Ulrich Somaini (2) · Da-Yeh University (1) · Federal University of São Paulo (1) · Hyunhwa Lee (1) · Jing Han (1) · Mersin University (1) · Papworth Hospital NHS Foundation Trust (1) · SEFA HAKTAN HATIK (1) · Sorlandet Hospital HF (1) · Stefan De Smet (1) · The First Affiliated Hospital with Nanjing Medical University (1) · Universidad Complutense de Madrid (1) · Universidade do Estado do Pará (1)
United States (6) · Turkey (Türkiye) (5) · China (2) · Switzerland (2) · Belgium (1) · Brazil (1) · Canada (1) · France (1) · Norway (1) · Spain (1) · United Kingdom (1)
Rodrigo Hoyos (2) · Silvia Ulrich (2) · Alan Yee, D.O. (1) · Carina R Fernee, PhD (1) · Gisele Sampaio Silva, PhD (1) · Gustavo Plaza-Manzano, PhD (1) · Mark Pereira, PhD (1) · Robert Gatherer, MBBS (1) · Stefan De Smet, Professor (1)
PMID 21658013, PMID 28742855, PMID 34135747, PMID 35571200, PMID 36081005, PMID 38703472, PMID 41343705, PMID 42859155, PMID 8598068