3 completed, 2 unknown, 1 withdrawn. 6 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 6 | Completed 3, Unknown 2, Withdrawn 1 |
Follow Head Injuries, Closed: new trials by email Literature Review of Head Injuries, Closed trials Research Report on Head Injuries, Closed
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Growth Hormone Deficiency in Mild Traumatic Brain Injury Growth Hormone, Placebo - Growth Hormone Treatment, Growth Hormone Deficiency | Early Phase 1 | Unknown | University of Calgary | 20 | 2023-02-01 | 2022-12-21 |
| Photobiomodulation to Improve Cognition in TBI, With fMRI Real LED Intervention, Sham LED Intervention - Traumatic Brain Injury, Closed Head Injury | Early Phase 1 | Unknown | Boston VA Research Institute, Inc. | 20 | 2019-08-07 | 2022-02-25 |
| Use of Adipose-Derived Stem/Stromal Cells in Concussion and Traumatic Brain Injuries Microcannula Harvest Adipose, Centricyte 1000, Sterile Normal Saline IV deployment AD-cSVF - Traumatic Encephalopathies, Chronic, Concussion, Mild | Early Phase 1 | Withdrawn | Robert W. Alexander, MD, FICS | 2018-11-30 | 2021-02-16 | |
| A Cohort Study Evaluating the Efficacy of PO Magnesium in the Treatment of Acute Traumatic Brain Injury in Adolescents Magnesium Oxide, Acetaminophen, Zofran ODT 4 MG Disintegrating Oral Tablet - Concussion Post Syndrome | Early Phase 1 | Completed | Corewell Health South | 17 | 2017-09-01 | 2024-11-29 |
| The Effectiveness of Osteopathic Manipulative Medicine in the Management of Headaches Associated With Post Concussion Syndrome Osteopathic Manipulative Therapy - Headache, Post-Concussion Syndrome | Early Phase 1 | Completed | Hackensack Meridian Health | 26 | 2017-08-01 | 2021-05-25 |
| Remediation of Impaired Self-Regulation in Patients With Mild TBI Tolcapone, Placebo - Mild Traumatic Brain Injury | Early Phase 1 | Completed | VA Office of Research and Development | 55 | 2015-08-01 | 2025-09-22 |
Brain Concussion (3) · Post-Concussion Syndrome (3) · Brain Injuries, Traumatic (2) · Headache (2) · Stress Disorders, Post-Traumatic (2) · Bronchiolitis Obliterans Syndrome (1) · Cognitive Dysfunction (1) · Dwarfism, Pituitary (1)
Craniocerebral Trauma (6) · Nervous System Diseases (6) · Trauma, Nervous System (6) · Wounds and Injuries (6) · Wounds, Nonpenetrating (6) · Brain Diseases (4) · Brain Injuries (4) · Central Nervous System Diseases (4) · Brain Concussion (2) · Brain Injuries, Traumatic (2) · Mental Disorders (2) · Neurologic Manifestations (2) · Pain (2) · Pathological Conditions, Signs and Symptoms (2)
Acetaminophen (1) · Growth Hormone (1) · Low-Level Light Therapy (1) · Magnesium Oxide (1) · Manipulation, Osteopathic (1) · Ondansetron (1) · Therapeutics (1) · Tolcapone (1)
Boston VA Research Institute, Inc. (1) · Corewell Health South (1) · Hackensack Meridian Health (1) · Robert W. Alexander, MD, FICS (1) · University of Calgary (1) · VA Office of Research and Development (1)
United States (5)
Alphonsa Thomas, DO (1) · Andrew S Kayser, MD PhD (1) · Chantel T Debert, MD, MSc (1) · Christopher Trigger, MD, CAQSM (1) · Glenn C Terry, MD (1) · Paula I Martin, PhD (1) · Robert W. Alexander, MD (1)
PMID 25723660, PMID 33879807, PMID 34253715
I01RX000825 (1)