7 recruiting, 4 completed, 3 unknown. 3 Not applicable, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Recruiting 2, Completed 1 |
| Phase 1 | 1 | Unknown 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow Frontotemporal Degeneration: new trials by email Literature Review of Frontotemporal Degeneration trials Research Report on Frontotemporal Degeneration
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vortioxetine for the Treatment of Mood and Cognitive Symptoms in Frontotemporal Dementia Vortioxetine - Fronto-temporal Dementia, Fronto-temporal Lobar Dementia | Phase 2 | Recruiting | Johns Hopkins University | 50 | 2025-03-20 | 2026-03-09 |
| Association of Transcranial Alternating Current Stimulation with Digital Cognitive Training for Cognitive Remediation in Older Adults Transcranial Alternating Current Stimulation, Digital Cognitive Training - Cognitive Dysfunction, Alzheimer Disease | Not applicable | Recruiting | Universidade Federal do Rio de Janeiro | 40 | 2024-12-02 | 2024-12-13 |
| IL-2 Plus Abatacept in FTD Abatacept plus Aldesleukin - Frontotemporal Degeneration | Phase 1 | Unknown | The Methodist Hospital Research Institute | 10 | 2024-05-06 | 2025-03-10 |
| Advances in Telephone-based Cognitive Screening Procedures Telephone-based neuropsychological assessment - ALS, Telephone-based neuropsychological assessment - AD, LBD, FTD and CVD, Telephone-based and in-person cognitive screening - NIs - Amyotrophic Lateral Sclerosis, Alzheimer's Disease | Recruiting | Istituto Auxologico Italiano | 280 | 2023-10-25 | 2024-03-29 | |
| The Swedish BioFINDER - Memory Clinic Study Plasma Amyloid Probability Score 2 (APS 2) score, Plasma ptau217/nptau217, Plasma ptau217 - Mild Dementia, Mild Cognitive Impairment | Recruiting | Skane University Hospital | 1200 | 2022-12-01 | 2026-04-06 | |
| Telehealth-enabled Integrated Palliative Care for People With Dementia Telehealth Integrated Primary Care (TIPC) - Dementia of Alzheimer Type, Alzheimer Disease | Not applicable | Completed | Thomas Jefferson University | 50 | 2022-06-29 | 2025-02-12 |
| In Vivo PET of Synaptic Density in Cognitive Disorders [18F]-SynVesT-1 - Alzheimer Disease, Frontotemporal Degeneration | Completed | Universitaire Ziekenhuizen KU Leuven | 134 | 2022-04-11 | 2026-01-08 | |
| Clearance Mechanisms in Atypical Neurodegenerative Diseases Neurodegenerative Diseases, Frontotemporal Degeneration | Unknown | Ludwig-Maximilians - University of Munich | 80 | 2022-04-01 | 2023-03-09 | |
| Comprehensive Analysis Platform To Understand, Remedy and Eliminate ALS Amyotrophic Lateral Sclerosis, Primary Lateral Sclerosis | Recruiting | University of Alberta | 150 | 2021-09-12 | 2026-04-13 | |
| The Swedish BioFINDER - Primary Care Study Plasma APS 2 score, Plasma p-tau217/np-tau217, Plasma p-tau217 - Mild Dementia, Mild Cognitive Impairment | Recruiting | Skane University Hospital | 1200 | 2020-01-01 | 2026-04-06 | |
| Voices Of Individuals: Challenges and Experiences Of bvFTD Telephone Interview - Frontotemporal Dementia, Frontotemporal Degeneration | Completed | University of Pennsylvania | 26 | 2019-06-26 | 2026-01-12 | |
| The Swedish BioFINDER 2 Study Flutemetamol F18 Injection, [18F]-RO6958948, Elecsys (Roche) Abeta42, Ttau and Ptau - Dementia, Alzheimer Disease | Not applicable | Recruiting | Skane University Hospital | 2950 | 2017-05-15 | 2026-04-06 |
| Study of Social Behavior and Emotion in Frontotemporal Dementia, Alzheimer's Disease and Controls Frontotemporal Dementia, Frontotemporal Degeneration | Unknown | University of California, Los Angeles | 99 | 2010-01-01 | 2011-10-28 | |
| Cognitive Impairement In Frontotemporal Dementia None-Observation Only - Frontotemporal Degeneration, Progressive Supranuclear Palsy | Completed | University of Pennsylvania | 997 | 2003-07-01 | 2020-11-12 |
Alzheimer Disease (8) · Lewy Body Disease (7) · Frontotemporal Dementia (5) · Cognitive Dysfunction (4) · Dementia, Vascular (4) · Amyotrophic Lateral Sclerosis (3) · Dementia (3) · Pick Disease of the Brain (3) · Disease (2) · Multiple System Atrophy (2) · Supranuclear Palsy, Progressive (2) · Behavior (1) · Cerebrovascular Disorders (1) · Corticobasal Degeneration (1) · Disease Progression (1)
Nervous System Diseases (13) · Central Nervous System Diseases (12) · Neurodegenerative Diseases (12) · Brain Diseases (11) · Neurocognitive Disorders (10) · Mental Disorders (9) · Tauopathies (9) · Basal Ganglia Diseases (8) · Movement Disorders (8) · Synucleinopathies (8) · Dementia (7) · Metabolic Diseases (7) · Nutritional and Metabolic Diseases (7) · Parkinsonian Disorders (7) · Proteostasis Deficiencies (7)
Abatacept (1) · Interviews as Topic (1) · Magnetic Resonance Imaging (1) · SynVesT-1 (1) · Transcranial Direct Current Stimulation (1) · Vortioxetine (1) · aldesleukin (1)
Skane University Hospital (3) · University of Pennsylvania (2) · Istituto Auxologico Italiano (1) · Johns Hopkins University (1) · Ludwig-Maximilians - University of Munich (1) · The Methodist Hospital Research Institute (1) · Thomas Jefferson University (1) · Universidade Federal do Rio de Janeiro (1) · Universitaire Ziekenhuizen KU Leuven (1) · University of Alberta (1) · University of California, Los Angeles (1)
United States (6) · Sweden (3) · Belgium (1) · Brazil (1) · Canada (1) · Germany (1) · Italy (1)
Erik Stomrud, MD, PhD (2) · Christopher Morrow, MD (1) · Erik Stomrud, MD, Phd (1) · Jill Owczarzak, PhD (1) · Koen Van Laere, MD, PhD, DSc (1) · Lori Erby, PhD, ScM (1) · Mario F Mendez, MD, PhD (1) · Robert Perneczky, Prof. Dr. (1) · Rogerio Panizzutti, Professor (1) · Sanjay Kalra, MD (1)
PMID 34937781, PMID 38347458, PMID 41343582, PMID 41864233, PMID 42219995, PMID 42348024
K23AG088248 (1), R01AG034499 (1)