38 completed, 11 unknown, 8 terminated, 4 not yet recruiting. 67 Phase 2, 7 Phase 3, 5 Phase 1.
Follow Foot Diseases: new trials by email Literature Review of Foot Diseases trials Research Report on Foot Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Performance of ComBatic™ Antimicrobial Wound Care Products in Hard-to-Heal Wounds Irrigation Solution for wounds, Hydrogel for wound care - Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer), Chronic Wound Care | Phase 2 | Not yet recruiting | University of Calgary | 96 | 2027-01-01 | 2026-10-14 |
| NAC-REPAIR for Post-surgical Pain NAC, NAC 0mg/day (Placebo) - Carpal Tunnel Surgery, Trigger Finger Disorder | Phase 2 | Not yet recruiting | University of Arizona | 80 | 2026-10-15 | 2026-07-17 |
| A Double-Blinded Study on Rapid and Sustained Pain Relief Topical Cannabidiol for Plantar Fasciitis transdermal CBD cream (Tolcylen®, Marlinz Pharma), Matched Placebos - Plantar Fasciitis | Phase 2 | Not yet recruiting | University of Florida | 50 | 2026-09-01 | 2026-09-03 |
| Effects of Transcutaneous Photobiomodulation on Diabetic Foot Ulcers. PBM - Photobiomodulation, Placebo PBM, Standard Treatment - Diabetes Mellitus, Foot Ulcer | Phase 2 | Recruiting | University of Nove de Julho | 20 | 2026-05-12 | 2026-09-04 |
| Efficacy of Extracorporeal Shockwave Therapy on Plantar Fasciitis in Patients With Peripheral Neuropathy Extracorporeal shockwave therapy (ESWT) - Neuropathic Pain, Plantar Fasciitis | Phase 2 | Not yet recruiting | National Taiwan University Hospital | 114 | 2026-05-01 | 2026-05-14 |
| Evaluate Use of Tropocells(R) Autologous Platelet-rich Fibrin (PRF) for Wagner Grade 1 and Grade 2, Mild to Mod Neuroischemic Plantar Diabetic Foot Ulcer Wound Care. Platelet Rich Plasma - Diabetic Foot Ulcer, Type 1 Diabetes Mellitus | Phase 2 | Recruiting | Estar Medical dba Medical Technologies, LTD | 30 | 2025-04-15 | 2025-06-12 |
| Evaluation of the Safety and Efficacy of Live ASCs in the Treatment of Diabetic Foot Syndrome. Allogeneic ADSC/ASC (alloADSC-DFU-RL), Placebo (PL-DFU-RL) - Diabetic Foot Ulcer | Phase 2 | Recruiting | Medical University of Warsaw | 105 | 2025-03-05 | 2026-10-26 |
| Topical Tolnaftate Stick for Tinea Pedis: An Open-Label Interventional Study 1% Tolnaftate Stick Formula A, 1% Tolnaftate Stick Formula B, 1% Tolnaftate Stick Formula C - Tinea Pedis | Phase 2 | Recruiting | Propedix, Inc. | 150 | 2024-12-30 | 2025-11-28 |
| Phase 2a Multi-Center Prospective, Randomized Trial to Evaluate the Safety & Efficacy of Topical PEP-TISSEEL for Diabetic Foot Ulcers (DFU) PEP (Purified Exosome Product) / TISSEEL - Diabetic Foot Ulcer | Phase 2 | Completed | Rion Inc. | 59 | 2024-02-27 | 2026-07-20 |
| A Study to Assess Collagenase Clostridium Histolyticum (CCH) in the Treatment of Plantar Fasciitis (PFA) Collagenase Clostridium Histolyticum (CCH), Placebo - Plantar Fasciitis | Phase 2 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 231 | 2024-01-03 | 2025-09-30 |
| A Novel Approach to Plantar Fasciitis in the Aging Population minimal shoes and foot strengthening and flexibility exercises, Supportive Footwear, foot orthotic device and foot flexibility exercises - Plantar Fasciitis, Chronic | Phase 2 | Unknown | University of South Florida | 138 | 2023-08-07 | 2024-05-21 |
| Painless Sharp Wound Debridement With Lidocaine-23%-Tetra-caine-7% Gel Versus EMLA 5% Cream IMP2 (lidocaine-23%-tetracaine-7% gel), IMP1 (EMLA 5% cream) - Ulcus Cruris, Ecthyma | Phase 2 | Unknown | Juerg Hafner | 40 | 2023-06-01 | 2023-06-06 |
| Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers Deferoxamine, Placebo - Diabetic Foot Ulcer | Phase 2 | Unknown | Karolinska University Hospital | 174 | 2022-12-30 | 2022-05-26 |
| A Trial to Evaluate the Safety and Efficacy of DBI-001 Gel, DBI-002 Gel, and Aqueous Gel in Subjects With Tinea Pedis DBI-001 Gel, DBI-002 Gel, Aqueous Gel - Tinea Pedis | Phase 2 | Unknown | DermBiont, Inc. | 24 | 2022-09-08 | 2023-02-14 |
| The Efficacy of Botulinum Toxin vs. Corticosteroid for the Treatment of Refractory Plantar Fasciitis Botulinum Toxin A, Dexamethasone - Plantar Fasciitis | Phase 2 / Phase 3 | Completed | Western Institute for Veterans Research | 62 | 2022-08-23 | 2025-04-02 |
| Nu-3 Topical Gel for Treatment of Diabetic Foot Ulcer 5% Bisphosphocin Topical Gel, Placebo Topical Gel, 10% Bisphosphocin Topical Gel - Chronic Diabetic Foot Ulcers | Phase 2 | Terminated | Lakewood-Amedex Inc | 3 | 2022-03-11 | 2024-01-30 |
| Efficacy, Safety, and Tolerability, of EN3835 vs Placebo in the Treatment of Plantar Fibromatosis EN3835, Placebo - Plantar Fibromatosis | Phase 2 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 176 | 2021-11-29 | 2026-03-27 |
| Iontophoresis of Treprostinil to Enhance Wound Healing in Diabetic Foot Skin Ulcers Treprostinil iontophoresis, Remodulin® placebo iontophoresis - Diabetic Foot Ulcer | Phase 1 / Phase 2 | Terminated | University Hospital, Grenoble | 4 | 2020-01-28 | 2023-12-12 |
| Evaluating the Safety and Effect of abobotulinumtoxinA in the Gastrocnemius Muscle to Improve Equinus and Plantar Fasciitis Pain AbobotulinumtoxinA 300 UNT - Plantar Fasciitis, Plantar Fasciitis, Chronic | Phase 2 | Unknown | University Foot and Ankle Foundation | 30 | 2019-11-20 | 2020-09-24 |
| Treatment of Chronic Wounds in Diabetic Foot Syndrome With Allogeneic Adipose Derived Mesenchymal Stem Cells Application of allogeneic ADSC stem cells in fibrin gel, Standard care in diabetic foot ulcer - Diabetic Foot Ulcer | Phase 1 / Phase 2 | Completed | Medical University of Warsaw | 46 | 2019-07-01 | 2021-10-14 |
Showing 20 of 67. Sign in to see all of them.
Foot Ulcer (30) · Diabetic Foot (22) · Diabetes Mellitus (17) · Tinea Pedis (17) · Fasciitis, Plantar (14) · Leg Ulcer (5) · Morton Neuroma (4) · Diabetes Complications (3) · Diabetes Mellitus, Type 2 (2) · Diabetic Neuropathies (2) · Infections (2) · Peripheral Nervous System Diseases (2) · Skin Diseases (2) · Ulcer (2)
Skin and Connective Tissue Diseases (50) · Skin Diseases (47) · Skin Ulcer (29) · Endocrine System Diseases (25) · Leg Ulcer (25) · Pathological Conditions, Signs and Symptoms (25) · Signs and Symptoms (23) · Cardiovascular Diseases (22) · Vascular Diseases (22) · Diabetic Angiopathies (21) · Musculoskeletal Diseases (21) · Diabetic Neuropathies (20) · Diabetes Complications (19) · Nutritional and Metabolic Diseases (19)
Botulinum Toxins, Type A (3) · 2-(2-(4-chlorophenyl)ethoxy)adenosine (2) · CNTX-4975 (2) · Dexamethasone (2) · Standard of Care (2) · Terbinafine (2) · 1-(2-(2,4-dichlorophenyl)-2-(4-(trifluoromethyl)benzyloxy)ethyl)-1H-imidazole (1) · Adrenal Cortex Hormones (1) · Atorvastatin (1) · BANG polymer gel (1) · Braces (1) · Bupivacaine (1) · Ciprofloxacin (1) · Cortisone (1) · Deferoxamine (1)
Revance Therapeutics, Inc. (3) · Centrexion Therapeutics (2) · DermBiont, Inc. (2) · Endo USA Inc., a Keenova Therapeutics Company (2) · Medical University of Warsaw (2) · Pfizer (2) · AlgoRx Pharmaceuticals (1) · Almirall, S.A. (1) · AmDerma (1) · Asker & Baerum Hospital (1) · Bayer (1) · Biotec Pharmacon ASA (1) · Carlos E Salas (1) · Chinese University of Hong Kong (1) · CoMentis (1)
United States (38) · Canada (3) · Germany (3) · Brazil (2) · Dominican Republic (2) · India (2) · Poland (2) · Russia (2) · Taiwan (2) · Bahrain (1) · China (1) · Denmark (1) · France (1) · Iran (1) · New Zealand (1)
Aamina M Khan (1) · Adrianne P Smith, MD (1) · Ahsan J Butt (1) · Babak Baravarian, DPM (1) · Beata Mrozikiewicz-Rakowska, . Assoc.Prof. (1) · Beata Mrozikiewicz-Rakowska, Assoc.Prof. (1) · Benjamin S. Rasmussen, MD (1) · Carl Schanbacher, MD (1) · Christoph Willers, MD, MBA (1) · Cracowski Jean-luc, Professor (1) · David G Armstrong, DPM MD PhD (1) · David Prior (1) · Emma Taylor, Ph.D (1)
PMID 11991474, PMID 16556754, PMID 20923537, PMID 21255460, PMID 22349369, PMID 22673486, PMID 24330156, PMID 24760263, PMID 25411598, PMID 25857939, PMID 26116717, PMID 27638453, PMID 29564750, PMID 33735146, PMID 35507774, PMID 35844773, PMID 39313976
2004 (1), 2008 (1), 2009 (1), 2016 (1), R01AG071646 (1), R15AR054507 (1), R44DK059074 (1)