16 completed, 4 recruiting, 2 unknown, 1 suspended. 25 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 25 | Completed 16, Recruiting 4, Unknown 2, Suspended 1, Terminated 1, Withdrawn 1 |
Follow Eye Manifestations: new trials by email Literature Review of Eye Manifestations trials Research Report on Eye Manifestations
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Real-Time Magnetic Device Prototype for Temporary Management of Paralytic Lagophthalmos Magnetic device prototype - Paralytic Lagophthalmos | Not applicable | Suspended | E-DA Hospital | 12 | 2026-08-01 | 2025-08-14 |
| Effect of Systemic Ozone Therapy on Corneal Endothelium Systemic Ozone Therapy - Corneal Endothelial Cell Loss, Ozone Therapy | Not applicable | Completed | Yuzuncu Yil University | 96 | 2026-01-14 | 2026-07-21 |
| A Clinical Study to Determine What Effect the EyeCool Treatment Has on the Eye's Surface Anatomy and Inflammation Response After Being Treated for Having Chronic Ocular Surface Pain (COSP) Topical Ophthalmic Cooling - Eye Pain | Not applicable | Recruiting | EyeCool Therapeutics, Inc. | 5 | 2025-08-25 | 2026-05-26 |
| Effect of Vitamin C Supplementation in Corneal Endothelial Damage in Phacoemulsification of Patients with Hard Cataracts Oral Vitamin C, Placebo - Endothelial Cell Loss, Corneal, Cataract and Intraocular Lens (IOL) Surgery | Not applicable | Recruiting | Universitas Indonesia | 120 | 2024-12-07 | 2025-01-17 |
| Study of the ETX-4143 2.0 Device in Subjects With Eye Pain ETX-4143 2.0 - Eye Pain | Not applicable | Completed | EyeCool Therapeutics, Inc. | 31 | 2024-08-01 | 2025-08-22 |
| Self-Adhering Magnetic Device to Treat Corneal Exposure temporary magnetic system for tarsorrhaphy (MST) - Paralytic Lagophthalmos, Corneal Exposure | Not applicable | Recruiting | University of Illinois at Chicago | 25 | 2024-04-17 | 2026-05-22 |
| Efficacy of Quantum Molecular Resonance in Neuropathic Corneal Pain and Corneal Nerve Regeneration Quantum Molecular Resonance (QMR) Treatment - Neuropathic Corneal Pain | Not applicable | Recruiting | Singapore Eye Research Institute | 30 | 2023-11-01 | 2025-09-19 |
| Alternating and Direct Current Stimulation for Neuropathic Eye Pain DC-Stimulator Plus (NeuroConn GmbH, Germany), Sooma direct current stimulator (Sooma, Finland) - Eye Pain, Neuropathy, Optic | Not applicable | Completed | Neil Lagali | 20 | 2023-06-16 | 2026-07-13 |
| Multisensory Stimulation in Infants for Eye Examination Multisensorial Stimulation - Premature Retinopathy, Pain, Eye | Not applicable | Completed | Akdeniz University | 80 | 2023-06-06 | 2023-12-22 |
| Pilot Study of TENS for Ocular Pain High frequency forehead TENS, Low frequency forehead TENS - Eye Pain | Not applicable | Completed | VA Office of Research and Development | 39 | 2022-10-03 | 2026-06-10 |
| Nictavi Tarsus Patch for Managing Lagophthalmos Tarsus Patch - Lagophthalmos | Not applicable | Completed | Angeline Nguyen | 20 | 2022-03-30 | 2023-07-21 |
| Anterior Versus Posterior Artisan Intraocular Lens Fixation in Aphakic Children With Insufficient Capsular Support. Anterior enclavation, Posterior enclavation - Cataracts Infantile, Subluxation of Lens | Not applicable | Completed | Cairo University | 32 | 2022-01-01 | 2024-05-02 |
| Comparison of Phacoemulsification and Corneal Damage Between FLACS and Standard Phaco With Two Handpieces Femtosecond laser assisted cataract surgery with Active Sentry handpiece, Standard phacoemulsification with the Active Sentry handpiece, Standard phacoemulsification with the OZil handpiece - Corneal Endothelial Cell Loss, Cataract | Not applicable | Withdrawn | Centre hospitalier de l'Université de Montréal (CHUM) | 2021-12-01 | 2026-03-19 | |
| Effect of Trigeminal Nerve Stimulation on Corneal Nerves and Chronic Ocular Pain Trigeminal Nerve Stimulation - Dry Eye, Neuropathic Pain | Not applicable | Completed | Instituto de Oftalmología Fundación Conde de Valenciana | 7 | 2021-02-03 | 2022-01-18 |
| Modified Tarsorrhaphy vs Gold Weight Implant for Paralytic Lagophthalmos in Leprosy Patients Modified Tarsorrhaphy, Gold Weight Implant - Paralytic Lagophthalmos, Leprosy--Patients | Not applicable | Completed | Yunia Irawati | 19 | 2019-05-09 | 2021-06-29 |
| Corneal Endothelium After Phacoemulsification in Pseudo Exfoliation Syndrome phacoemulsification - Corneal Endothelial Cell Loss, Pseudoexfoliation Syndrome | Not applicable | Completed | Minia University | 40 | 2019-03-01 | 2022-09-13 |
| Comparison of Ectoin® Containing Eye Drops and Ectoin® Containing Eye Spray With the Eye Spray Tears Again® Ectoin® Allergy Eye Drops 2%, Ectoin® Eye Spray Colloidal, Tears Again® eye spray - Eye Manifestations | Not applicable | Completed | Bitop AG | 50 | 2019-01-01 | 2020-08-11 |
| Corneal Endothelial Cell Loss After Trabeculectomy Versus Phakotrabeculectomy Trabeculectomy, Phako-trabeculectomy - Corneal Endothelial Cell Loss, Glaucoma | Not applicable | Completed | Sunnybrook Health Sciences Centre | 25 | 2017-09-01 | 2023-04-13 |
| NMES to Improve Eyelid Functions in Cranial Nerve (CN) III and VII Palsy Neuromuscular electrical stimulation, Sham neuromuscular electrical stimulation - Blepharoptosis, Lagophthalmos | Not applicable | Terminated | Brooks Rehabilitation | 26 | 2017-01-06 | 2022-12-21 |
| Protecting the Corneal Endothelium During Cataract Surgery Using the Anterior Capsule Rhexis protection shield - Endothelial Cell Loss, Corneal | Not applicable | Completed | Prim. Prof. Dr. Oliver Findl, MBA | 70 | 2016-03-02 | 2019-02-26 |
Showing 20 of 25. Sign in to see all of them.
Corneal Endothelial Cell Loss (10) · Eye Pain (8) · Lagophthalmos (6) · Cataract (5) · Blepharoptosis (2) · Dry Eye Syndromes (2) · Neuralgia (2) · Aphakia (1) · Astigmatism (1) · Bell Palsy (1) · Brain Injuries (1) · Exfoliation Syndrome (1) · Facial Paralysis (1) · Fuchs' Endothelial Dystrophy (1)
Eye Diseases (25) · Pathological Conditions, Signs and Symptoms (20) · Signs and Symptoms (20) · Corneal Diseases (10) · Pathologic Processes (10) · Postoperative Complications (10) · Neurologic Manifestations (9) · Pain (8) · Eyelid Diseases (6) · Lens Diseases (6) · Nervous System Diseases (5) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Cranial Nerve Diseases (2) · Infections (2)
Ascorbic Acid (1) · Lasers (1) · Phacoemulsification (1) · Sulfur Hexafluoride (1) · Therapeutics (1) · Trabeculectomy (1) · Vitrectomy (1)
EyeCool Therapeutics, Inc. (2) · Sunnybrook Health Sciences Centre (2) · Akdeniz University (1) · Angeline Nguyen (1) · Bitop AG (1) · Brooks Rehabilitation (1) · Cairo University (1) · Centre hospitalier de l'Université de Montréal (CHUM) (1) · E-DA Hospital (1) · EDUARD PEDEMONTE-SARRIAS (1) · Evidence Based Cataract Study Group (1) · Instituto de Oftalmología Fundación Conde de Valenciana (1) · Kevin Houston (1) · Minia University (1) · Neil Lagali (1)
United States (5) · Canada (3) · Australia (2) · Egypt (2) · Indonesia (2) · Turkey (Türkiye) (2) · China (1) · Germany (1) · Iran (1) · Mexico (1) · Singapore (1) · Spain (1) · Sweden (1) · Taiwan (1)
Alireza Baradaran Raffiee, MD (1) · Angeline M Nguyen, MD (1) · Catherine Birt, MD (1) · Eduard Pedemonte-Sarrias, MD (1) · Elizabeth R Felix, PhD (1) · Georges Durr, MD, FRCSC (1) · Hatem Saeed, MD (1) · Kenneth Ngo, MD (1) · Kevin E Houston, OD (1) · Neil Lagali, PhD (1) · Patrick R Casey, OD (1) · Peter Kertes, MD, CM, FRCSC (1)
PMID 26305528, PMID 41812852, PMID 42099442, PMID 42101550, PMID 42455250