44 completed, 21 recruiting, 13 unknown, 4 terminated. 31 Not applicable, 16 Phase 2, 9 Phase 1, 8 Phase 3, 5 Phase 4.
Follow Fuchs' Endothelial Dystrophy: new trials by email Literature Review of Fuchs' Endothelial Dystrophy trials Research Report on Fuchs' Endothelial Dystrophy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Partial Range Of Field IOLs in DMEK-Enabled Procedures combined cataract and lamellar endothelial keratoplasty - Cataract, Fuchs Endothelial Corneal Dystrophy | Not applicable | Not yet recruiting | Universitair Ziekenhuis Brussel | 10 | 2026-10-01 | 2026-08-25 |
| Study of EO2002 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction 150K cells, 500K cells, Placebo - Corneal Edema, Fuchs | Phase 2 | Recruiting | Emmecell | 121 | 2026-10-01 | 2026-10-09 |
| Postoperative CCT in FECD vs. Non-FECD Fuchs Endothelial Corneal Dystrophy, Cataract (Post-operative Cataract Surgery Follow-up) | Not yet recruiting | Vienna Hospital Association | 98 | 2026-07-20 | 2026-08-10 | |
| Effect of Descemet Membrane Polishing in Fuchs Endothelial Corneal Dystrophy Fuchs Polishing - Fuchs Endothelial Corneal Dystrophy | Not applicable | Recruiting | Centre Hospitalier Universitaire de Saint Etienne | 20 | 2026-05-21 | 2026-05-26 |
| Effect of Donor Diabetes and Other Factors on Corneal Transplant Endothelial Cell Loss and Success at 5 Years Descemet membrane endothelial keratoplasty - Fuchs Endothelial Corneal Dystrophy, Corneal Endothelial Decompensation | Not applicable | Enrolling by invitation | Case Western Reserve University | 570 | 2025-12-03 | 2026-02-27 |
| Assessment of Corneal Endothelial Function Following Hypoxic Stress Wearing of contact lens - Fuchs' Endothelial Corneal Dystrophy | Phase 1 / Phase 2 | Withdrawn | Massachusetts Eye and Ear Infirmary | 2025-12-01 | 2026-03-02 | |
| Influence of Supine Positioning on the Outcomes After Descemet Membrane Endothelial Keratoplasty (DMEK) Duration of Supine Positioning - Fuchs Endothelial Corneal Dystrophy, Descemet Membrane Endothelial Keratoplasty (DMEK) | Not applicable | Recruiting | University Hospital Heidelberg | 102 | 2025-10-02 | 2026-01-28 |
| PVEK Corneal Implant For Treatment of Corneal Edema Precise Vision Endothelial Keratoplasty (PVEK) Implant - Corneal Edema, Fuchs' Endothelial Dystrophy | Phase 1 | Recruiting | Precise Bio | 15 | 2025-09-16 | 2026-01-12 |
| DT-168 in Keratoplasty Patients With Fuchs Endothelial Corneal Dystrophy DT-168 - Fuchs Endothelial Corneal Dystrophy, Fuchs | Phase 2 | Recruiting | Design Therapeutics, Inc. | 70 | 2025-07-30 | 2026-09-28 |
| The Effect of Topical Rho-kinase Inhibitors on Corneas of Patients With Fuchs Endothelial Corneal Dystrophy Netarsudil 0.02% Ophthalmic Solution, artificial tear substitute - Fuchs Endothelial Corneal Dystrophy, Cataract | Enrolling by invitation | University Hospital Dubrava | 50 | 2025-04-01 | 2026-09-09 | |
| Brillouin Microscopy Used to Evaluate Corneal Mechanical Properties Brillouin optical scanning system (Intelon Optics) (BOSS) - Map Dot Fingerprint Dystrophy, Post-penetrating Keratoplasty | Not applicable | Not yet recruiting | Vienna Institute for Research in Ocular Surgery | 100 | 2025-04-01 | 2025-04-06 |
| The Effects of Ripasudil in Patients With FED Undergoing Femtosecond Laser Assisted Cataract Surgery Ripasudil, Placebo - Fuchs' Endothelial Dystrophy, Cataract | Phase 3 | Recruiting | Singapore Eye Research Institute | 120 | 2025-03-01 | 2025-01-29 |
| Trial Comparing Cataract Surgery With Triple-DMEK in Patients With Cataract and Fuchs Endothelial Corneal Dystrophy Intervention group /arm 1 (Cataract surgery alone), Control group /arm 2: Corneal transplantation as Descemet Membrane Endothelial Keratoplasty (DMEK) in combination with cataract surgery (triple-DMEK) - Cataract Surgery, Cataract and Fuchs Endothelial Corneal Dystrophy | Not applicable | Recruiting | University of Cologne | 120 | 2025-01-24 | 2025-02-21 |
| Comparison of Outcomes Between Femtosecond Laser-Assisted and Conventional Phacoemulsification in Fuchs Endothelial Corneal Dystrophy Patients With Cataracts Fuchs Endothelial Corneal Dystrophy, Cataract | Recruiting | Eye & ENT Hospital of Fudan University | 120 | 2025-01-01 | 2025-06-17 | |
| Analysis of the Genotype/Phenotype Relationship in the Fuchs' Corneal Endothelial Dystrophy in France Genotyping, Histology, Collection of data - Corneal Dystrophies | Recruiting | Centre Hospitalier Universitaire de Saint Etienne | 500 | 2024-08-08 | 2026-05-06 | |
| The OPTIMISE Study Fluorometholone 0.1% Oph Susp, Dexamethasone 0.1% ophthalmic suspension, Stop steroids - Pseudophakic Bullous Keratopathy, Fuchs' Endothelial Dystrophy | Phase 4 | Recruiting | Maastricht University Medical Center | 342 | 2024-07-29 | 2025-10-06 |
| Plasma Rich in Growth Factors in Corneal Endothelial Transplantation Endothelial keratoplasty, PRGF - Fuchs' Endothelial Dystrophy, Corneal Edema | Not applicable | Recruiting | University of Miami | 100 | 2024-07-15 | 2026-04-09 |
| Prognosis of Posterior Lamellar Keratoplasty visual acuity comparaison - Fuchs' Endothelial Corneal Dystrophy, Pseudophakic Bullous Keratopathy | Recruiting | Centre Hospitalier Régional Metz-Thionville | 1000 | 2024-06-01 | 2026-06-24 | |
| FECD-TRACE: Fuchs' Endothelial Corneal Dystrophy TRAjectory and Correlation With Genotype in the United Kingdom Clinical phenotyping, CTG18.1 Expansion Status Genotyping - Fuchs Dystrophy, Fuchs' Endothelial Dystrophy | Recruiting | University College, London | 500 | 2024-02-01 | 2025-03-18 | |
| Prevalence of Fuchs Endothelial Corneal Dystrophy in a Population of Dermatology Patients. collection of medical data - Fuchs Endothelial Corneal Dystrophy | Completed | Centre Hospitalier Universitaire de Saint Etienne | 1200 | 2024-01-02 | 2025-08-12 |
Showing 20 of 92. Sign in to see all of them.
Cataract (13) · Corneal Edema (13) · Corneal Dystrophy, Posterior Polymorphous, 1 (8) · Corneal Diseases (5) · Keratoconus (5) · Corneal Dystrophies, Hereditary (3) · Corneal Endothelial Cell Loss (3) · Corneal endothelial dystrophy type 2 (3) · Epiretinal Membrane (2) · Iridocorneal Endothelial Syndrome (2) · Retinal Detachment (2) · Retinal Perforations (2) · Carcinoma (1) · Corneal Dystrophy, Congenital Stromal (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (92) · Eye Diseases (92) · Eye Diseases, Hereditary (92) · Genetic Diseases, Inborn (92) · Corneal Dystrophies, Hereditary (89) · Corneal Diseases (87) · Lens Diseases (13) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (5) · Eye Manifestations (3) · Pathologic Processes (3) · Postoperative Complications (3) · Iris Diseases (2) · Retinal Diseases (2) · Uveal Diseases (2)
K-115 (7) · Descemet Stripping Endothelial Keratoplasty (5) · Ophthalmic Solutions (5) · netarsudil (4) · Corneal Transplantation (3) · Cataract Extraction (2) · Phacoemulsification (2) · Acetylcysteine (1) · Amphotericin B (1) · BID protein, human (1) · Blood Specimen Collection (1) · Control Groups (1) · Dexamethasone (1) · Drug Implants (1) · Fluorometholone (1)
Centre Hospitalier Universitaire de Saint Etienne (5) · Cornea Research Foundation of America (4) · Massachusetts Eye and Ear Infirmary (4) · Centre Hospitalier Régional Metz-Thionville (3) · Kowa Research Institute, Inc. (3) · Maastricht University Medical Center (3) · Case Western Reserve University (2) · Centre Hospitalier Universitaire de Besancon (2) · Emmecell (2) · Legacy Health System (2) · Oregon Health and Science University (2) · Price Vision Group (2) · Singapore Eye Research Institute (2) · The Cleveland Clinic (2) · Trefoil Therapeutics, Inc. (2)
United States (40) · Germany (12) · France (11) · Denmark (7) · Spain (7) · Netherlands (5) · United Kingdom (5) · Belgium (4) · Canada (4) · Singapore (3) · Austria (2) · Mexico (2) · Armenia (1) · Australia (1) · China (1)
Francis W Price, Jr, MD (5) · Shona Pendse, MD, MMSc (3) · Bernard Delbosc, MD, PhD (2) · Jonathan Lass, MD (2) · Justis P Ehlers, MD (2) · Mark A Terry, MD (2) · Ula Jurkunas, MD (2) · Alfonso L Sabater, MD (1) · Alice Davidson, PhD (1) · Andy Yun, PhD (1) · Bernard Duchesne, MD, PhD (1) · Carina Koppen, MD, PhD (1) · David S. Rootman, MD (1)
PMID 34633355, PMID 17996211, PMID 19298950, PMID 19781456, PMID 19875170, PMID 20166622, PMID 21099412, PMID 21183511, PMID 21872938, PMID 21993468, PMID 22218143, PMID 22357383, PMID 22705345, PMID 22710494, PMID 22710497, PMID 23635858, PMID 24030086, PMID 24252821, PMID 24417895, PMID 24452215, PMID 24488132, PMID 24782469, PMID 24782475, PMID 24957432, PMID 25015214, PMID 25055146, PMID 25077834, PMID 25525173, PMID 26050537, PMID 26096520, PMID 26114817, PMID 26706619, PMID 26764881, PMID 26983976, PMID 27108095, PMID 27158810, PMID 27273977, PMID 27560030, PMID 28749899, PMID 29525615, PMID 29731147, PMID 32705337, PMID 33045216, PMID 33591041, PMID 33737034, PMID 33892048, PMID 33951443, PMID 34426402, PMID 35184123, PMID 35462618
1UG1EY030030-01A1 (1), 1UG1EY030039-01A1 (1), 1UG1EY037206-01 (1), 2016 (1), 2017 (1), 5UG1EY030030-05 (1), K23EY022947 (1), R01EY029023 (1)