30 completed, 13 unknown, 3 not yet recruiting, 3 recruiting. 14 Not applicable, 10 Phase 4, 8 Phase 2, 5 Phase 3, 4 Phase 1.
Follow Endophthalmitis: new trials by email Literature Review of Endophthalmitis trials Research Report on Endophthalmitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Efficacy of Intracameral Zimoxin for Prevention of Endophthalmitis After Cataract Surgery Moxifloxacin, Placebo - Endophthalmitis | Phase 2 / Phase 3 | Not yet recruiting | Jason Ahee, M.D. | 60000 | 2027-06-01 | 2026-09-15 |
| Vitrectomy Combined With Povidone-Iodine Vitreous Irrigation for Infectious Endophthalmitis Povidone-iodine intravitreal irrigation with povidone-iodine containing 0.0025% available iodine, BSS intravitreal irrigation solution - Endophthalmitis, Infectious Endophthalmitis | Not applicable | Not yet recruiting | Beijing Tongren Hospital | 38 | 2026-10-30 | 2026-10-22 |
| Targeting Immunosuppressive Treatment for Non-infectious Uveitis Using Aqueous Humor Cytokine Profiles to improve clinical practice in treatment of non-infective uveitis - Uveitis Posterior Non-Infectious, Inflammation Eye | Not applicable | Active not recruiting | University of Milan | 220 | 2025-11-15 | 2025-12-03 |
| Demographics and Clinical Characteristics of Ocular Inflammatory Diseases in Singapore No Intervention: Observational Cohort - Uveitis, Scleritis and Episcleritis | Active not recruiting | Singapore National Eye Centre | 200 | 2025-08-19 | 2025-09-16 | |
| First-line Surgical Versus Medical Treatment: A Retrospective Study From 2014 to 2024 in Brest (BRESTE) Early pars plana vitrectomy (PPV) with intravitreal antibiotics - Endophthalmitis | Completed | University Hospital, Brest | 170 | 2025-01-01 | 2026-04-21 | |
| Evaluation and Risk Factors of Post-traumatic Endophthalmitis ophthalmic saline eye drops, Saline - Endophthalmitis | Not yet recruiting | Assiut University | 41 | 2024-11-10 | 2024-11-05 | |
| Vascular Changes Associated With Endophthalmitis. Multimodal imaging findings - Endophthalmitis | Recruiting | Asociación para Evitar la Ceguera en México | 71 | 2024-11-01 | 2025-09-16 | |
| Efficacy and Safety of Topical Cyclosporine 0.05% and Lifitgrast on the Ocular Surface Symptom After Photorefractive Keratectomy in Feiz Hospital, Isfahan, 2024 Group 1 drug, Group 2: Drug and placebo, Group 3: Drug and palcebo - Ocular Surface Symptom, Ocular Surface Disease | Phase 1 | Unknown | Mohsen Pourazizi | 150 | 2024-10-30 | 2024-10-03 |
| Clinical Features and Visual Prognosis of Infectious Endophthalmitis Endophthalmitis | Completed | Zhongnan Hospital | 100 | 2024-06-01 | 2025-01-01 | |
| Effectiveness and Safety of 0.5% Moxifloxacin Hydrochloride Ophthalmic Solution in Perioperative Sterilization in Patients Undergoing Ophthalmic Surgery Moxifloxacin hydrochloride ophthalmic solution - Post Operative Endophthalmitis | Completed | Novartis Pharmaceuticals | 102 | 2024-01-27 | 2024-05-09 | |
| Phacovitrectomy Versus Pars Plana Vitrectomy Alone for Post-Intravitreal Injection Endophthalmitis Phacovitrectomy, Pars plana vitrectomy - Endophthalmitis, Endophthalmitis Postoperative | Not applicable | Completed | Benha University | 40 | 2024-01-15 | 2026-07-21 |
| Complex Ocular Infection, Optimization of Microbiological Diagnosis NGS for endohtalmitis / Multiplex PCR for keratitis - Endophthalmitis, Keratitis | Recruiting | Assistance Publique - Hôpitaux de Paris | 153 | 2023-11-21 | 2025-09-15 | |
| Ozurdex Endophtamitis Cohort, Prognostic Assessment at 12 Months Visual acuity analysis, Intraocular pressure analysis, Analysis of optical coherence tomography (OCT) images - Endophthalmitis | Unknown | Centre Hospitalier Universitaire de Saint Etienne | 8 | 2023-06-05 | 2024-02-20 | |
| Intracameral Antibiotic Safety Study Vancomycin, Moxifloxacin, Placebo - Intracameral Antibiotics, Cataract Surgery | Phase 3 | Suspended | Panhandle Eye Group, LLP | 500 | 2023-01-01 | 2022-04-27 |
| A Study of the Incidence of Intraocular Inflammation and Suspected Endophthalmitis Among Patients Treated With Aflibercept, Vial and Pre-filled Syringe, 2014-2022 Non Applicable - Intraocular Inflammation, Suspected Endophthalmitis | Completed | Regeneron Pharmaceuticals | 155413 | 2022-09-16 | 2023-12-01 | |
| Nanopore Sequencing in Ophthalmology Endophthalmitis | Recruiting | Medical University of Graz | 20 | 2022-04-22 | 2026-10-20 | |
| Safety and Efficacy of Topical Moxifloxacin for Prevention of Post-Traumatic Endophthalmitis: Randomized Controlled Clinical Trial Moxifloxacin Ophthalmic 0.5% Ophthalmic Solution, Ciprofloxacin 400 MG/200 ML Intravenous Solution [CIPRO IV] - Endophthalmitis, Open Globe Injury | Phase 2 | Unknown | University of Campinas, Brazil | 100 | 2021-12-10 | 2021-12-17 |
| Use Of Intracameral Moxifloxacin For Prophylaxis Of Open Globe Endophthalmitis Intraocular Instillation Solution, Moxifloxacin Ophthalmic - Endophthalmitis, Trauma, Corneal | Phase 4 | Unknown | Federal University of São Paulo | 100 | 2021-10-01 | 2021-11-10 |
| Study of Intraocular Concentrations (Aqueous Humor, Vitreous Humor) of Antibiotics After Local and/or Systemic Administration in Endophthalmitis Pharmacokinetic and pharmacodynamic study of antibiotics used in severe endophthalmitis from samples taken from treated patients - Endophthalmitis | Not applicable | Unknown | Fondation Hôpital Saint-Joseph | 5 | 2020-12-09 | 2023-03-07 |
| Intravitreal Triamcinolone and Moxifloxacin Injection After Cataract Surgery intra-vitreal triamcinolone-moxifloxacin injection after cataract surgery as a prophylactic measures against post-operative endophthalmitis - Pharmacological Action | Not applicable | Completed | Emad Abdel Aal Saliem | 84 | 2020-12-03 | 2022-06-27 |
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Cataract (7) · Eye Infections (5) · Inflammation (5) · Uveitis (4) · Keratitis (3) · Eye Pain (2) · Macular Degeneration (2) · Bacterial Infections (1) · Breast Neoplasms (1) · COVID-19 (1) · Carcinoma, Non-Small-Cell Lung (1) · Conjunctivitis (1) · Corneal Injuries (1) · Corneal Ulcer (1)
Infections (58) · Eye Diseases (57) · Eye Infections (53) · Lens Diseases (7) · Pathological Conditions, Signs and Symptoms (6) · Pathologic Processes (5) · Corneal Diseases (4) · Retinal Diseases (4) · Uveal Diseases (4) · Endocrine System Diseases (2) · Eye Manifestations (2) · Lung Diseases (2) · Neoplasms (2) · Neoplasms by Site (2) · Nervous System Diseases (2)
Moxifloxacin (6) · Cefazolin (2) · Cefuroxime (2) · Dexamethasone (2) · Ophthalmic Solutions (2) · Paracentesis (2) · Sodium Chloride (2) · Ciprofloxacin (1) · Clindamycin (1) · Cyclosporins (1) · Exercise (1) · Fluorometholone (1) · Gatifloxacin (1) · Gentamicins (1) · Intracameral Injection (1)
Federal University of São Paulo (3) · University of Campinas, Brazil (3) · Benha University (2) · National Eye Institute (NEI) (2) · Universidade Federal de Pernambuco (2) · Asociación para Evitar la Ceguera en México (1) · Assistance Publique - Hôpitaux de Paris (1) · Assiut University (1) · Azienda USL Reggio Emilia - IRCCS (1) · Beijing Tongren Hospital (1) · Biogen (1) · Centre Hospitalier Universitaire de Saint Etienne (1) · Chiang Mai University (1) · City, University of London (1) · Emad Abdel Aal Saliem (1)
United States (11) · Brazil (9) · France (5) · Egypt (4) · Italy (4) · Germany (3) · Austria (2) · Canada (2) · Iran (2) · United Kingdom (2) · Belgium (1) · China (1) · India (1) · Indonesia (1) · Kenya (1)
Ahmed A Abdelshafy, MD (1) · Alessandro Invernizzi, MD (1) · Bita Esmaeli, MD (1) · Dan Gradin, MD (1) · Donald Mazzulla, MD (1) · Emad A Saliem (1) · Fernando Paganelli, MD (1) · Harvey S Uy, MD (1) · Herminia Mino de Kapsar, PhD (1)
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