17 completed, 10 unknown, 6 recruiting, 5 withdrawn. 18 Not applicable, 9 Phase 1, 6 Phase 2, 4 Phase 3, 1 Early Phase 1.
Follow Corneal Injuries: new trials by email Literature Review of Corneal Injuries trials Research Report on Corneal Injuries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| IN PATIENTS WITH CORNEAL ABRASIONS TREATED WITH COLLAGEN CORNEAL SHIELDS IN THE EMERGENCY DEPARTMENT SETTING Oasis 72-Hour collagen shield, sham collagen shield - Corneal Abrasions | Not applicable | Not yet recruiting | Milton S. Hershey Medical Center | 60 | 2026-11-15 | 2026-07-13 |
| Eyelid Taping Alone Versus Taping With Lubricant Eye Drops for Perioperative Corneal Protection Hypoallergenic Eyelid Taping, Hypoallergenic Eyelid Taping With Lubricant Eye Drops - Corneal Injury, Exposure Keratopathy | Not applicable | Not yet recruiting | Fatih Sultan Mehmet Training and Research Hospital | 200 | 2026-06-01 | 2026-05-07 |
| Losartan for Corneal Fibrosis Topical losartan, Placebo Control - Corneal Scarring Fibrosis | Not applicable | Recruiting | Universidad Autonoma de Nuevo Leon | 46 | 2026-02-12 | 2026-05-08 |
| A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis Bullosa KB803, Placebo - Dystrophic Epidermolysis Bullosa, DEB - Dystrophic Epidermolysis Bullosa | Phase 3 | Recruiting | Krystal Biotech, Inc. | 16 | 2025-06-20 | 2026-03-12 |
| A Natural History Study of Corneal Abrasions in Patients With Dystrophic Epidermolysis Bullosa (DEB) Epidermolysis Bullosa Dystrophica, Epidermolysis Bullosa Dystrophica, Recessive | Recruiting | Krystal Biotech, Inc. | 40 | 2024-08-02 | 2025-07-02 | |
| Validation of the Use of Terahertz Scanning System on Corneal Scars and Corneal Edema THz scanning using THz Imaging system. - Corneal Diseases, Corneal Scars and Opacities | Recruiting | Singapore Eye Research Institute | 150 | 2024-07-01 | 2025-05-21 | |
| Study to Evaluate the Clinical Safety and Performance of the CorNeat KPro for Treatment of Corneal Blindness CorNeat KPro - Corneal Disease, Corneal Opacity | Not applicable | Terminated | CorNeat Vision Ltd. | 15 | 2024-06-27 | 2026-05-07 |
| Pilot Study of ELK-003 Eye Drops for Treating Ocular Manifestations of Epidermolysis Bullosa ELK-003 (Standarized Amniotic Fluid Secretome Eye Drops) - Junctional Epidermolysis Bullosa, Epidermolysis Bullosa (EB) | Phase 1 | Active not recruiting | Fundación DEBRA Chile, Niños Piel de Cristal | 20 | 2024-05-07 | 2025-12-31 |
| Role of AS-OCT in Assessment of Corneal Perforation anterior segment optical coherence tomography - Corneal Perforation | Completed | Minia University | 13 | 2024-04-15 | 2024-07-23 | |
| Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Corneal Scars CSB-001 Ophthalmic Solution 0.1% - Corneal Scar | Phase 1 | Recruiting | Claris Biotherapeutics, Inc. | 20 | 2024-02-05 | 2026-04-07 |
| The Debridement To Treat The Traumatic Corneal Abrasion corneal debridement of corneal abrasion - Corneal Abrasion | Not applicable | Unknown | Zhongshan Ophthalmic Center, Sun Yat-sen University | 156 | 2022-12-31 | 2022-09-09 |
| CDL Validation Study Eyes Dry Chronic, Chronic Conjunctivitis of Both Eyes | Completed | Occyo GmbH | 104 | 2022-04-22 | 2024-04-04 | |
| The Role of OmniLenz® in the Treatment of Small Corneal Perforations Secondary to Exposure Keratitis in ICU Patients OmniLenz® - Corneal Perforation, Exposure Keratitis | Phase 2 / Phase 3 | Completed | Farwaniya Hospital | 5 | 2022-04-10 | 2024-08-06 |
| fMRI and IVCM Cornea Microscopy of CXL in Keratoconus Pain, Postoperative, Pain, Chronic | Recruiting | Boston Children's Hospital | 60 | 2021-10-04 | 2025-12-19 | |
| Use Of Intracameral Moxifloxacin For Prophylaxis Of Open Globe Endophthalmitis Intraocular Instillation Solution, Moxifloxacin Ophthalmic - Endophthalmitis, Trauma, Corneal | Phase 4 | Unknown | Federal University of São Paulo | 100 | 2021-10-01 | 2021-11-10 |
| To Evaluate the Clinical Safety and Efficacy of Limbal Stem Cell for Treatment of Superficial Corneal Pathologies". Ex-vivo cultivated Allogeneic limbal stromal stem cells - Corneal Scars and Opacities | Early Phase 1 | Unknown | L.V. Prasad Eye Institute | 20 | 2021-07-01 | 2021-06-21 |
| First in Human (FIH) Study to Assess Safety and Efficacy of the CorNeat KPro for the Treatment of Corneal Blindness CorNeat KPro - Corneal Disease, Corneal Opacity | Not applicable | Terminated | CorNeat Vision Ltd. | 10 | 2021-01-03 | 2024-09-24 |
| Pilot Study to Investigate the Feasibility, Reliability and Efficacy of Utilizing OCT to Automate PROSE Fitting Ocular surface optical coherence tomography - Keratoconus, Ocular Surface Disease | Not applicable | Completed | Boston Sight | 11 | 2020-12-15 | 2023-10-27 |
| A Novel Sandwich Technique of Minimally Invasive Keratoplasty for Corneal Perforation Corneal Perforation, Corneal Stromal Lenticule,Sandwich Technique | Unknown | Tianjin Eye Hospital | 30 | 2020-10-23 | 2024-01-31 | |
| Keratoconus, Corneal Diseases and Transplant Registry Corneal Diseases, Keratoconus | Unknown | University Hospital, Montpellier | 800 | 2019-12-01 | 2020-12-29 |
Showing 20 of 45. Sign in to see all of them.
Corneal Diseases (9) · Corneal Perforation (7) · Corneal Opacity (6) · Keratoconus (4) · Corneal Ulcer (3) · Epidermolysis Bullosa Dystrophica (3) · Eye Injuries (3) · Dry Eye Syndromes (2) · Glaucoma (2) · Keratitis (2) · Limbal Stem Cell Deficiency (2) · Pterygium (2) · Acute Pain (1) · Agnosia (1)
Craniocerebral Trauma (45) · Eye Diseases (45) · Facial Injuries (45) · Nervous System Diseases (45) · Trauma, Nervous System (45) · Wounds and Injuries (45) · Eye Injuries (42) · Corneal Diseases (36) · Pathological Conditions, Signs and Symptoms (8) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (5) · Eye Infections (5) · Genetic Diseases, Inborn (5) · Infections (5) · Keratitis (5)
Ophthalmic Solutions (3) · Carboxymethylcellulose Sodium (1) · Contact Lenses (1) · Fibrin Tissue Adhesive (1) · Hydrocodone (1) · Inlays (1) · Insulin (1) · Intracameral Injection (1) · Losartan (1) · Lubricant Eye Drops (1) · Punctal Plugs (1) · Saline Solution (1) · Slit Lamp (1) · Sodium Chloride (1) · Solutions (1)
L.V. Prasad Eye Institute (3) · CorNeat Vision Ltd. (2) · Krystal Biotech, Inc. (2) · Minia University (2) · Ann & Robert H Lurie Children's Hospital of Chicago (1) · Boston Children's Hospital (1) · Boston Sight (1) · Centre hospitalier de l'Université de Montréal (CHUM) (1) · Centro Hospitalar de Vila Nova de Gaia/Espinho, E.P.E. (1) · Chungnam National University (1) · Claris Biotherapeutics, Inc. (1) · Farwaniya Hospital (1) · Fatih Sultan Mehmet Training and Research Hospital (1) · Federal University of São Paulo (1) · Fondation Ophtalmologique Adolphe de Rothschild (1)
United States (15) · France (5) · Canada (3) · Israel (3) · Austria (2) · China (2) · Egypt (2) · India (2) · Netherlands (2) · Brazil (1) · Chile (1) · Kuwait (1) · Mexico (1) · Portugal (1) · Singapore (1)
Vivek Singh, MSc PhD (2) · Adam M Au, DO MD PHD (1) · Ahmed A Abdelghany, MD (1) · Ahmed A Abdelghany, professor (1) · Alexander Levit, FCOptom (1) · Bourcier Tristan, PHMD (1) · Bruce Evans, PhD (1) · Chang-sik Kim, MD, PhD (1) · Daniel Brocks, MD (1) · Dr.Sayan Basu, MBBS.MS (1) · Dr.Vivek Singh, PhD (1) · Eric A Moulton, OD PhD (1) · Fatemeh Doostmohammadi, MD (1) · Fung-Rong Hu, MD (1) · Hamid Gourabi, PhD (1)
PMID 35622535, PMID 25504883, PMID 19505676, PMID 23974663, PMID 24672709, PMID 26203760, PMID 33121832, PMID 34483270, PMID 34623187, PMID 40038272, PMID 40152603, PMID 41327137