6 recruiting. 3 Phase 1, 2 Phase 2, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Recruiting 3 |
| Phase 2 | 2 | Recruiting 2 |
| Early Phase 1 | 1 | Recruiting 1 |
Follow Embryonal Tumor With Multilayered Rosettes: new trials by email Literature Review of Embryonal Tumor With Multilayered Rosettes trials Research Report on Embryonal Tumor With Multilayered Rosettes
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| B7-H3.CD28Z.CART in CNS Neoplasms B7-H3.CD28Z.CART, Fludarabine, Cyclophosphamide - Central Nervous System Neoplasms, Brain Tumor | Phase 1 | Recruiting | Robbie Majzner | 70 | 2026-09-01 | 2026-09-03 |
| Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas Eflornithine (DFMO), AMXT 1501 Dicaprate - Atypical Teratoid/Rhabdoid Tumor, Embryonal Tumor With Multilayered Rosettes | Phase 1 / Phase 2 | Recruiting | Milton S. Hershey Medical Center | 265 | 2026-05-13 | 2026-09-03 |
| Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation Cytarabine IT, hydrocortisone, Cisplatin - CNS Embryonal Tumor, CNS, Medulloblastoma | Early Phase 1 | Recruiting | C17 Council | 15 | 2025-09-23 | 2026-07-14 |
| Embryonal Tumor With Multilayered Rosettes Radiotherapy (RT), Chemotherapy Drug, Cancer - Physician's Choice, Non-Investigational Surgical Resection - Embryonal Tumor With Multilayered Rosettes, Embryonal Tumor With Multilayered Rosettes, Nos | Phase 2 | Recruiting | University of California, San Francisco | 70 | 2025-03-06 | 2026-06-29 |
| Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT) Multi-tumor antigen specific cytotoxic T lymphocytes (TSA-T) directed against proteogenomically determined personalized tumor-specific antigens (TSA), Group A Standard-of-Care Backbone Therapy, Group B Salvage Backbone Therapy - Medulloblastoma, Childhood, Atypical Teratoid/Rhabdoid Tumor of CNS | Phase 1 | Recruiting | Children's National Research Institute | 12 | 2024-09-20 | 2026-10-13 |
| ETMR One: An International Registry and Research Platform for Children With Embryonal Tumor With Multilayer Rosettes Embryonal Tumor With Multilayered Rosettes | Recruiting | Hackensack Meridian Health | 100 | 2020-07-12 | 2026-06-02 |
Neuroectodermal Tumors, Primitive (6) · Rhabdoid Tumor (4) · Medulloblastoma (3) · Pinealoma (3) · Central Nervous System Neoplasms (2) · Ependymoma (2) · Neuroblastoma (2) · Pyloric Stenosis, Hypertrophic (2) · Brain Neoplasms (1) · Diffuse Intrinsic Pontine Glioma (1) · Meningeal Neoplasms (1) · Osteosarcoma (1) · Sarcoma, Ewing (1)
Neoplasms (6) · Neoplasms by Histologic Type (6) · Neoplasms, Germ Cell and Embryonal (6) · Neoplasms, Glandular and Epithelial (6) · Neoplasms, Nerve Tissue (6) · Neoplasms, Neuroepithelial (6) · Neuroectodermal Tumors (6) · Neoplasms by Site (5) · Nervous System Diseases (5) · Nervous System Neoplasms (5) · Brain Diseases (4) · Central Nervous System Diseases (4) · Glioma (4) · Neoplasms, Complex and Mixed (4) · Brain Neoplasms (3)
Cyclophosphamide (2) · Temozolomide (2) · Blood Specimen Collection (1) · Carboplatin (1) · Celecoxib (1) · Cisplatin (1) · Drug Therapy (1) · Eflornithine (1) · Etoposide (1) · Filgrastim (1) · Granulocyte Colony-Stimulating Factor (1) · Hydrocortisone (1) · Isotretinoin (1) · Mesna (1) · Radiotherapy (1)
C17 Council (1) · Children's National Research Institute (1) · Hackensack Meridian Health (1) · Milton S. Hershey Medical Center (1) · Robbie Majzner (1) · University of California, San Francisco (1)
United States (5) · Canada (1)
Derek Hanson, MD (2) · Annie Huang (1) · Brian Rood, MD (1) · Giselle Saulnier Sholler, MD (1) · Lucie Lafay-Cousin (1) · Sabine Mueller, MD, PhD, MAS (1) · Susan Chi (1) · Sylvia Cheng (1)