17 completed, 3 active not recruiting, 3 recruiting, 3 terminated. 16 Not applicable, 4 Phase 1, 2 Early Phase 1, 1 Phase 4.
Follow Dysplasia: new trials by email Literature Review of Dysplasia trials Research Report on Dysplasia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Real-time Molecular Diagnosis of Oral Precancer LIP device - Oral Cancer, Dysplasia | Completed | King's College London | 40 | 2025-12-11 | 2026-08-27 | |
| A Study Collecting Health Information to Understand and Prevent Gastric Cancer Questionnaire - Gastric Atrophy, Gastric Intestinal Metaplasia | Recruiting | Memorial Sloan Kettering Cancer Center | 3200 | 2024-04-11 | 2026-01-30 | |
| Image Enhanced Endoscopy IBD Image Enhanced Endoscopy Filters - Inflammatory Bowel Diseases, Dysplasia | Not applicable | Unknown | Royal Perth Hospital | 270 | 2024-04-03 | 2024-04-12 |
| Artificial Intelligence and Dysplasia Detection in Inflammatory Bowel Disease (EIIDISIA Study) CADe system, NBI - Inflammatory Bowel Diseases, Dysplasia | Not applicable | Active not recruiting | Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana | 122 | 2023-11-15 | 2025-08-15 |
| Study of VEGF-A Targeting NIR-II Fluorescence Endoscopy in the Gastrointestinal Tract Bev-ICG, NIR-II fluorescence endoscopy platform - Gastrointestinal Carcinoma, Dysplasia | Phase 1 | Recruiting | Institute of Automation, Chinese Academy of Sciences | 30 | 2023-07-20 | 2025-05-13 |
| IBD Neoplasia Surveillance RCT Standard colonoscopy with targeted biopsies - Colonic Neoplasms, Inflammatory Bowel Diseases | Not applicable | Completed | Ottawa Hospital Research Institute | 1411 | 2022-09-23 | 2026-07-07 |
| A Study Comparing the Effectiveness of EndoRotor Versus Radiofrequency in Treating Barrett's Esophagus Endorotor, Radiofrequency - Barrett Esophagus, Dysplasia | Not applicable | Recruiting | University Hospital, Angers | 140 | 2022-03-25 | 2026-06-30 |
| A Proof-of-Concept Study Evaluating LINFU™ LINFU™ - Pancreas Adenocarcinoma, Dysplasia | Not applicable | Completed | Adenocyte, LLC | 12 | 2021-10-21 | 2024-02-20 |
| Artificial Intelligence and Dysplasia Detection in Ulcerative Colitis (CUDISIA Study) DiscoveryTM, iSCAN - Ulcerative Colitis, Dysplasia | Not applicable | Completed | Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana | 50 | 2021-05-05 | 2024-06-11 |
| Surveillance in Ulcerative Colitis: Narrow Band Image Versus Chromoendoscopy for High-risk Groups chromoendoscopy with target biopsy; NBI with target biopsy - Ulcerative Colitis, Dysplasia | Not applicable | Unknown | Asan Medical Center | 188 | 2020-12-01 | 2020-11-24 |
| IBD Neoplasia Surveillance Pilot RCT Intervention Group, Control Group - Inflammatory Bowel Diseases, Colonic Neoplasms | Not applicable | Completed | Ottawa Hospital Research Institute | 600 | 2020-11-06 | 2023-03-31 |
| Acetic Acid for the Detection of Esophageal Neoplasms Acetic acid chromoendoscopy, Seattle protocol - Barretts Esophagus With Low Grade Dysplasia, Dysplasia | Not applicable | Suspended | Coordinación de Investigación en Salud, Mexico | 76 | 2019-07-03 | 2025-04-24 |
| Oral Epithelial Dysplasia Informational Needs Questionnaire No intervention is planned for this study - Oral Epithelial Dysplasia, Precancerous Conditions | Completed | University College, London | 128 | 2018-10-31 | 2020-04-02 | |
| Effects of Avmacol® in the Oral Mucosa of Patients Following Curative Treatment for Tobacco-related Head and Neck Cancer Avmacol - Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma (HNSCC) | Not applicable | Completed | University of Pittsburgh | 6 | 2018-07-27 | 2023-04-07 |
| Broccoli Sprout Extract in Preventing Recurrence in Patients With Tobacco-Related Head and Neck Squamous Cell Cancer Avmacol® - HNSCC, Head and Neck Cancer | Early Phase 1 | Completed | University of Arizona | 6 | 2017-04-24 | 2021-06-21 |
| Swallowable Sponge Cell Sampling Device and Next Generation Sequencing in Detecting Esophageal Cancer in Patients With Low or High Grade Dysplasia, Barrett Esophagus, or Gastroesophageal Reflux Disease Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis, Quality-of-Life Assessment - Barrett Esophagus, Dysplasia | Not applicable | Completed | OHSU Knight Cancer Institute | 11 | 2016-08-03 | 2020-11-25 |
| Multimodal Imaging for Surveillance in Patients With Oral Potentially Malignant Disorders Biopsy, Fluorescence Imaging, High-Resolution Microendoscopy - Dysplasia, Lip and Oral Cavity Carcinoma | Early Phase 1 | Active not recruiting | M.D. Anderson Cancer Center | 63 | 2016-05-25 | 2026-10-15 |
| The Value of I-Scan and Confocal Laser Endomicroscopy for the Assessment of Chronic Inflammatory Bowel Disease Confocal laser endomicroscopy - Inflammatory Bowel Disease, Crohn's Disease | Terminated | University of Medicine and Pharmacy Craiova | 15 | 2015-06-01 | 2018-01-17 | |
| Phase II Evaluation of AHCC for the Eradication of HPV Infections AHCC 3 grams once a day, Placebo - Human Papilloma Virus, Dysplasia | Not applicable | Completed | The University of Texas Health Science Center, Houston | 50 | 2015-04-01 | 2021-01-20 |
| VEGF-targeted Fluorescence Near-Infrared (NIR) Endoscopy in (Pre)Malignant Esophageal Lesions Bevacizumab-IRDye800CW, Near infrared fluorescence endoscopy platform - Esophageal Cancer, Dysplasia | Phase 1 | Completed | University Medical Center Groningen | 14 | 2014-04-01 | 2024-04-16 |
Showing 20 of 30. Sign in to see all of them.
Inflammatory Bowel Diseases (5) · Barrett Esophagus (4) · Colitis, Ulcerative (4) · Adenocarcinoma Of Esophagus (3) · Esophageal Squamous Cell Carcinoma (3) · Hyperplasia (3) · Mouth Neoplasms (3) · Carcinoma in Situ (2) · Colonic Neoplasms (2) · Gastroesophageal Reflux (2) · Head and Neck Neoplasms (2) · Metaplasia (2) · Mouth Diseases (2) · Squamous Cell Carcinoma of Head and Neck (2) · Crohn Disease (1)
Neoplasms (18) · Digestive System Diseases (17) · Gastrointestinal Diseases (16) · Neoplasms by Site (15) · Gastroenteritis (10) · Pathological Conditions, Signs and Symptoms (9) · Digestive System Neoplasms (8) · Head and Neck Neoplasms (8) · Intestinal Diseases (8) · Esophageal Diseases (7) · Gastrointestinal Neoplasms (7) · Pathologic Processes (7) · Colonic Diseases (6) · Carcinoma (5) · Carcinoma, Squamous Cell (5)
Biopsy (3) · 2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-a (1) · Active Hexose Correlated Compound (1) · Endoscopy (1) · Endoscopy, Digestive System (1) · Erlotinib Hydrochloride (1) · Narrow Band Imaging (1) · Optical Imaging (1) · Proflavine (1) · Surveys and Questionnaires (1) · Vaginal Smears (1)
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (2) · OHSU Knight Cancer Institute (2) · Ottawa Hospital Research Institute (2) · Adenocyte, LLC (1) · Asan Medical Center (1) · Coordinación de Investigación en Salud, Mexico (1) · Hôpital Edouard Herriot (1) · Institute of Automation, Chinese Academy of Sciences (1) · King's College London (1) · M.D. Anderson Cancer Center (1) · Mattias Block (1) · Memorial Sloan Kettering Cancer Center (1) · National Cancer Institute (NCI) (1) · Peking University (1) · Roswell Park Cancer Institute (1)
United States (12) · France (3) · United Kingdom (3) · Canada (2) · China (2) · Netherlands (2) · Spain (2) · Australia (1) · Mexico (1) · Romania (1) · Sweden (1)
Adrian Saftoiu, MD PhD FASGE (1) · Ann Gillenwater (1) · Chris Pelt (1) · Dan P Zandberg, MD (1) · Dong-Hoon Yang, MD, PhD (1) · Frans TM Peters, MD PhD (1) · Hassan Arshad, MD (1) · James Dolan (1) · Jim Hitchin (1) · John Hunter (1) · Judith A Smith, Pharm.D. (1) · Julie E. Bauman, MD, MPH (1)
PMID 25828079, PMID 29247063, PMID 29306867, PMID 29861609, PMID 30809788, PMID 33840743, PMID 34091519, PMID 35814366, PMID 37625408, PMID 37732496, PMID 38297397, PMID 38403900, PMID 38457759, PMID 38740327, PMID 38995686, PMID 40635115, PMID 41523838, PMID 41765898, PMID 42410417
N01CN35157 (1), P30CA016672 (1), P30CA060553 (1), P30CA069533 (1), P50CA097190 (1)