10 completed, 10 unknown, 2 recruiting, 2 terminated. 25 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 25 | Completed 10, Unknown 10, Recruiting 2, Terminated 2, Withdrawn 1 |
Follow Drug Eruptions: new trials by email Literature Review of Drug Eruptions trials Research Report on Drug Eruptions
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Electroacupuncture Combined With Self-administered Acupressure for the Prevention of Capecitabine-Associated Hand-Foot Syndrome True electroacupuncture + True self-administered acupressure, Doctor-prescribed treatment, Sham electroacupuncture + Sham self-administered acupressure - Capecitabine, Hand-foot Syndrome | Not applicable | Recruiting | Affiliated Hospital of Qinghai University | 220 | 2024-10-08 | 2024-12-12 |
| The Efficacy and Safety of Liangxue Ointment in the Treatment of Hand-foot Syndrome Caused by VEGFR-TKI Drugs Liangxue ointment（Traditional Chinese Ointment）, Urea cream - Hand-Foot Syndrome | Not applicable | Unknown | Peking University Cancer Hospital & Institute | 220 | 2024-03-25 | 2024-09-04 |
| The Efficacy of Acupuncture and Laser Acupuncture in Treating Chemotherapy or Target Therapy-induced Hand-foot Syndrome acupuncture, laser acupuncture, Sham-laser acupuncture - Hand-Foot Syndrome | Not applicable | Unknown | China Medical University Hospital | 60 | 2023-08-01 | 2023-07-18 |
| Efficacy and Safety of Moisturising Cream With or Without Vitamin E and Urea Cream in Palmar-plantar Erythrodysesthesia Moisturising cream with vitamin E concentrate, Moisturising cream without vitamin E concentrate, Urea cream - Palmar-Plantar Erythrodysesthesia, Palmar-Plantar Erythrodysesthesia Due to Cytotoxic Therapy | Not applicable | Completed | Sarawak General Hospital | 145 | 2023-05-16 | 2026-01-14 |
| Ice Plant Intensive Cream for the Prevention of Hand-Foot Syndrome in Breast Cancer: Pilot Randomized Controlled Trial Ice Plant Intensive Cream plus Standard Care, Standard Care - Hand-Foot Syndrome, Breast Cancer | Not applicable | Completed | University Hospital Tuebingen | 15 | 2023-03-10 | 2026-05-06 |
| Efficacy of Extra Virgin Olive Oil (EVOO) Supplementation on Hand-Foot Syndrome Incidence in Patients With Capecitabine Extra Virgin Olive Oil, Olive Oil, Placebo - Hand and Foot Skin Reaction, Hand and Foot Syndrome | Not applicable | Unknown | Universitas Sriwijaya | 60 | 2023-01-01 | 2024-01-03 |
| Study To Evaluate The Efficacy Of Tofacitinib In Patients With SJS/TEN Tofacitinib - Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis | Not applicable | Completed | Chang Gung Memorial Hospital | 20 | 2022-08-01 | 2025-09-16 |
| Photobiomodulation Therapy in the Management of Hand-foot Syndrome and Hand-foot Skin Reaction Photobiomodulation therapy (PBMT) - Hand-foot Syndrome, Hand-foot Skin Reaction | Not applicable | Recruiting | Jessa Hospital | 40 | 2022-01-12 | 2023-06-18 |
| Meibomian Gland Probing in the Sub-Acute Phase of Patients With Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Maskin Probe - Stevens-Johnson Syndrome, Toxic Epidermal Necrolyses | Not applicable | Unknown | Massachusetts Eye and Ear Infirmary | 30 | 2021-12-01 | 2021-12-06 |
| The Preventive Effect of Chemotherapy-induced Hand-foot Syndrome Chinese traditional medicine nursing combined with case tracking management, Health Education - Cancer | Not applicable | Unknown | Peking University Third Hospital | 130 | 2021-01-01 | 2024-06-04 |
| Acetylated Natural Nucleotides in Treating Hand-foot Syndrome Gel containing Acetylated Natural Nucleotides, Vehicle Gel - Hand-foot Syndrome | Not applicable | Completed | Nan xu | 21 | 2020-11-03 | 2023-03-01 |
| Evaluation of Tangible Boost for Patients With Stevens Johnson Syndrome, Sjogren's Syndrome, and Graft Vs Host Disease Tangible Boost, Placebo - Stevens-Johnson Syndrome, Graft Versus Host Disease in Eye | Not applicable | Terminated | Tangible Science | 28 | 2020-02-24 | 2026-10-28 |
| HLA Screening in Reducing the Risk of Antiepileptic Drug-induced Cutaneous Adverse Reactions HLA screening before commencing aromatic AEDs - Epilepsy, Neuropathy | Not applicable | Unknown | Second Affiliated Hospital of Guangzhou Medical University | 4000 | 2017-08-01 | 2018-09-05 |
| Testing the Effectiveness of Henna on Managing PPE Henna, Placebo - Palmar-plantar Erythrodysesthesia (PPE) | Not applicable | Completed | Cyprus University of Technology | 56 | 2017-06-01 | 2019-10-25 |
| Evaluating the Effect of Isotretinoin in Regulatory T-cell Function in Adverse Cutaneous Drug Eruptions (ACDEs): A Pilot Study Isotretinoin, Placebo - Toxic Epidermal Necrolysis | Not applicable | Withdrawn | Massachusetts General Hospital | 2016-11-01 | 2023-06-07 | |
| Minor Salivary Gland Transplantation for Cicatrizing Conjunctivitis minor salivary gland transplantation - Cicatrizing Conjunctivitis, Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum | Not applicable | Unknown | National Taiwan University Hospital | 30 | 2016-09-01 | 2019-02-15 |
| The Topical Application of Vitamin B6 in Palmar-Plantar Erythrodysesthesia Vitamin B6 cream, Placebo Vitamin B6 cream - Palmar-Plantar Erythrodysesthesia | Not applicable | Completed | Cyprus University of Technology | 54 | 2016-07-01 | 2018-08-07 |
| HLA-B*5801 Screening to Prevent Allopurinol-induced Severe Cutaneous Adverse Reaction HLA-B*5801 test - Stevens-Johnson Syndrome, Kidney Failure, Chronic | Not applicable | Unknown | Seoul National University Hospital | 600 | 2016-02-24 | 2017-02-08 |
| Safety and Performance Study of the ARGOS-IO System in Patients Undergoing Boston Keratoprosthesis Implantation ARGOS-IO system - Graft vs Host Disease, Congenital Aniridia | Not applicable | Completed | Implandata Ophthalmic Products GmbH | 13 | 2015-03-01 | 2025-02-27 |
| Comparison Between Corticosteroid and Topical Steroids in the DRESS Prednisone, Clobetasol - Drug Rash With Eosinophilia and Systemic Symptoms | Not applicable | Unknown | Assistance Publique - Hôpitaux de Paris | 112 | 2013-10-01 | 2015-07-30 |
Showing 20 of 25. Sign in to see all of them.
Hand-Foot Syndrome (13) · Stevens-Johnson Syndrome (10) · Dry Eye Syndromes (3) · Neoplasms (3) · Aniridia (2) · Breast Neoplasms (2) · Drug Hypersensitivity Syndrome (2) · Epilepsy (2) · Sjogren's Syndrome (2) · Blepharospasm (1) · Bronchiolitis Obliterans Syndrome (1) · Burns, Chemical (1) · Carcinoma, Renal Cell (1) · Gastrointestinal Neoplasms (1) · Graft vs Host Disease (1)
Chemically-Induced Disorders (25) · Dermatitis (25) · Drug Hypersensitivity (25) · Drug-Related Side Effects and Adverse Reactions (25) · Skin Diseases (25) · Skin and Connective Tissue Diseases (25) · Hypersensitivity (12) · Hypersensitivity, Delayed (12) · Immune System Diseases (12) · Erythema (10) · Erythema Multiforme (10) · Mouth Diseases (10) · Skin Diseases, Vesiculobullous (10) · Stomatitis (10)
Acupuncture Therapy (1) · Anticonvulsants (1) · Blood Specimen Collection (1) · Clobetasol (1) · Isotretinoin (1) · Low-Level Light Therapy (1) · Olive Oil (1) · Prednisone (1) · Pyridoxine (1) · Standard of Care (1) · Vitamin B 6 (1) · lawsone (1) · tofacitinib (1)
Cyprus University of Technology (2) · Affiliated Hospital of Qinghai University (1) · Assistance Publique - Hôpitaux de Paris (1) · Chang Gung Memorial Hospital (1) · China Medical University Hospital (1) · Cook County Health (1) · Federal University of São Paulo (1) · Implandata Ophthalmic Products GmbH (1) · Jessa Hospital (1) · Massachusetts Eye and Ear Infirmary (1) · Massachusetts General Hospital (1) · Nan xu (1) · National Taiwan University Hospital (1) · Peking University Cancer Hospital & Institute (1) · Peking University Third Hospital (1)
China (5) · United States (4) · Belgium (2) · Cyprus (2) · France (2) · Germany (2) · Taiwan (2) · Brazil (1) · Indonesia (1) · Israel (1) · Malaysia (1) · South Korea (1)
Aaron Sulkes, MD (1) · Arturo Saavedra, MD, PhD (1) · Carina Koppen, MD, PhD (1) · Chun Bing Chen (1) · Hsiao-Sang Chu, MD, MS (1) · Jeroen Mebis, MD, PhD (1) · Karen Carrasquillo, OD, PhD (1) · Marie J Tassignon, MD, PhD (1) · Nadia Zakaria, MBBS, PhD (1) · Nan Xu, M.D. (1) · Pei Jye Voon, M.D (1) · Rinat Yerushalmi, MD (1) · Susan McDunn, MD (1)
PMID 21940785, PMID 24795111, PMID 25592341, PMID 28715540, PMID 33227569, PMID 33538338, PMID 33626423, PMID 36054263, PMID 37075722, PMID 38754628, PMID 42741060