Hypersensitivity, Delayed: Clinical Trials

199 completed, 77 unknown, 40 recruiting, 25 terminated. 110 Not applicable, 77 Phase 2, 32 Phase 3, 30 Phase 1, 29 Phase 4.

By phase and status

Phase	Trials	Status
Not applicable	110	Completed 56, Unknown 29, Recruiting 9, Active not recruiting 4, Terminated 4, Enrolling by invitation 3, Withdrawn 3, Not yet recruiting 2
Phase 2	77	Completed 36, Terminated 12, Not yet recruiting 9, Withdrawn 9, Recruiting 4, Unknown 4, Active not recruiting 3
Phase 3	32	Completed 18, Unknown 5, Active not recruiting 3, Terminated 3, Recruiting 2, Not yet recruiting 1
Phase 1	30	Completed 16, Not yet recruiting 3, Terminated 3, Withdrawn 3, Recruiting 2, Unknown 2, Active not recruiting 1
Phase 4	29	Completed 11, Unknown 5, Not yet recruiting 4, Recruiting 3, Terminated 3, Withdrawn 2, Active not recruiting 1
Early Phase 1	6	Completed 3, Unknown 2, Enrolling by invitation 1

Follow Hypersensitivity, Delayed: new trials by email Literature Review of Hypersensitivity, Delayed trials Research Report on Hypersensitivity, Delayed

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Outcomes in Stevens Johnsons Syndrome and Toxic Epidermal Necrolysis Site specific standard of care comparison - Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis		Withdrawn	Massachusetts General Hospital		2030-01-01	2026-01-16
Interest of a Targeted Therapy for the Treatment of a Severe Form of Hypersensitivity to Drug (DRESS Syndrome) Benralizumab 30 MG/ML [Fasenra], Placebo Comparator: Placebo-Control Arm 0.9% Sodium Chloride - DRESS Syndrome	Phase 2	Not yet recruiting	University Hospital, Lille	96	2027-01-06	2026-05-15
LAM-001 for the Treatment of Sarcoidosis Associated Pulmonary Hypertension (SAPH) Placebo, LAM-001 - Sarcoidosis Associated Pulmonary Hypertension	Phase 2	Not yet recruiting	IRulya Therapeutics Inc.	60	2026-12-01	2026-10-21
A Clinical Trial of Tulisokibart (MK-7240) in Participants With Pulmonary Sarcoidosis (MK-7240-016) Tulisokibart, Placebo, Background prednisone therapy - Pulmonary Sarcoidosis	Phase 2	Not yet recruiting	Merck Sharp & Dohme LLC	158	2026-11-06	2026-10-09
Evaluation of the Efficacy and Safety of Compound Betamethasone in Pulmonary Sarcoidosis Prednisone, Compound betamethasone - Sarcoidosis, Pulmonary	Phase 2 / Phase 3	Not yet recruiting	Peking Union Medical College Hospital	126	2026-11-01	2026-10-15
Cardiac Imaging in Systemic Disorders: the ORACLES Registry data collection - Lupus		Not yet recruiting	Assistance Publique - Hôpitaux de Paris	1500	2026-11-01	2026-02-13
An Efficacy Study of XTMAB-16 in Patients With Pulmonary Sarcoidosis With or Without Extrapulmonary Manifestations XTMAB-16, Placebo - Pulmonary Sarcoidosis	Phase 2	Not yet recruiting	Xentria, Inc.	182	2026-10-30	2026-10-21
Use of Silk Fibroin Dressings in Primary Total Hip Arthroplasty Dermabond PRINEO, Silk fibroin - Allergic Contact Dermatitis (ACD)	Not applicable	Not yet recruiting	The University of Texas Health Science Center, Houston	350	2026-10-15	2026-10-09
Gabapentin vs. Benzonatate vs. Standard of Care for Cough in ILD Gabapentin, Benzonatate 200 mg, Standard of care treatment for ILD - Interstitial Lung Disease	Phase 4	Not yet recruiting	Post Graduate Institute of Medical Education and Research, Chandigarh	177	2026-10-07	2026-10-08
Subconjunctival Humira for Boston Keratoprosthesis Adalimumab Injection - Penetrating Keratoplasty, Multiple Graft Failure	Phase 1	Not yet recruiting	Massachusetts Eye and Ear Infirmary	8	2026-10-01	2026-08-31
Reliability of Expired Allergens in Patch Testing: A Comparative Study With Non-Expired Series Patch 1 (Expired), Patch 2 (non-expired) - Allergic Contact Dermatitis	Phase 4	Not yet recruiting	University of Calgary	100	2026-09-01	2026-08-14
Early Prediction of Outcomes Following Optic Neuritis: Development and Acceptability of a Prognostic Tool No Intervention: Observational Cohort - Optic Neuritis, Multiple Sclerosis		Not yet recruiting	King's College London	180	2026-09-01	2026-07-15
FAPI PET Imaging - An Exploratory Study [18F]FAPI-74 PET/CT - Thyroid Pathology, Head and Neck Cancer (H&N)	Phase 1 / Phase 2	Not yet recruiting	Martin Huellner	770	2026-08-01	2026-07-15
Exosome-based Omic Signatures of Disease Activity in Cardiac Sarcoidosis (EXODACS) Exosome Analysis - Cardiac Sarcoidosis, Sarcoidosis of the Heart		Recruiting	Mayo Clinic	115	2026-07-13	2026-08-17
A Comparison of a Medication Adherence Platform (FORTISKAP™) vs. Usual Care in Subjects on Oral Medications for the Treatment of Interstitial Lung Disease, Sarcoid and Pulmonary Hypertension Idiopathic Pulmonary Fibrosis (IPF), Sarcoidosis Lung		Not yet recruiting	Cosmos Rx, Inc	100	2026-07-01	2026-05-29
Evaluation of Hypersensitivity Reactions to Silk Fibroin Versus 2-octyl Cyanoacrylate Mesh in Shoulder Surgery Silk fibroin (SYLKE), 2-octyl cyanoacrylate mesh (Dermabond PRINEO) - Hypersensitivity Reactions, Allergic Contact Dermatitis	Not applicable	Not yet recruiting	The University of Texas Health Science Center, Houston	350	2026-06-30	2026-05-14
A Trial of Baricitinib in Patients With Cardiac Sarcoidosis Baricitinib (LY3009104) 4 mg - Cardiac Sarcoidosis	Phase 2	Not yet recruiting	Stanford University	10	2026-04-01	2026-02-10
Corticosteroid Tapering in Sarcoidosis Standard prednisolone taper, Fast prednisolone taper - Sarcoidosis	Not applicable	Recruiting	Royal Brompton & Harefield NHS Foundation Trust	100	2026-03-19	2026-03-27
Diagnostic Value of EBUS-Guided Transbronchial Mediastinal Cryobiopsy Versus Conventional Bronchoscopic Approaches for Stage I/II Sarcoidosis EBUS-TBNA-based sampling methods, EBUS-TBMC based sampling method - Sarcoidosis, Pulmonary	Not applicable	Active not recruiting	China-Japan Friendship Hospital	469	2026-03-01	2026-08-06
Virtual Patient Groups for Sarcoidosis Associated Fatigue Virtual Mindfulness Based Stress Reduction Group, Virtual sarcoidosis support group - Sarcoidosis, Fatigue	Not applicable	Recruiting	The Cleveland Clinic	100	2026-02-26	2026-04-24

Showing 20 of 396. Sign in to see all of them.

Narrower conditions

Sarcoidosis (248)  ·  Sarcoidosis, Pulmonary (66)  ·  Dermatitis, Allergic Contact (49)  ·  Stevens-Johnson Syndrome (40)  ·  Lung Diseases, Interstitial (32)  ·  Pulmonary Fibrosis (21)  ·  Lung Neoplasms (17)  ·  Tuberculosis (17)  ·  Idiopathic Pulmonary Fibrosis (15)  ·  Hypertension, Pulmonary (14)  ·  Lymphoma (14)  ·  Fatigue (13)  ·  Inflammation (12)  ·  Pulmonary Disease, Chronic Obstructive (12)

Broader conditions

Immune System Diseases (396)  ·  Hypersensitivity (387)  ·  Hemic and Lymphatic Diseases (281)  ·  Lymphatic Diseases (281)  ·  Lymphoproliferative Disorders (279)  ·  Respiratory Tract Diseases (141)  ·  Skin and Connective Tissue Diseases (128)  ·  Lung Diseases (125)  ·  Skin Diseases (121)  ·  Dermatitis (97)  ·  Pathological Conditions, Signs and Symptoms (81)  ·  Lung Diseases, Interstitial (69)  ·  Pathologic Processes (63)  ·  Skin Diseases, Eczematous (56)

Interventions

Prednisone (11)  ·  Patch Tests (8)  ·  Blood Specimen Collection (7)  ·  Bronchoscopy (7)  ·  Adalimumab (6)  ·  Infliximab (6)  ·  Adrenocorticotropic Hormone (5)  ·  Azithromycin (5)  ·  Bronchoalveolar Lavage (5)  ·  Sodium Chloride (5)  ·  Observation (4)  ·  Prednisolone (4)  ·  Ethambutol (3)  ·  Hydroxychloroquine (3)  ·  Levofloxacin (3)

Sponsors

Assistance Publique - Hôpitaux de Paris (17)  ·  University of Cincinnati (15)  ·  Post Graduate Institute of Medical Education and Research, Chandigarh (13)  ·  Maastricht University Medical Center (8)  ·  National Heart, Lung, and Blood Institute (NHLBI) (8)  ·  Hospices Civils de Lyon (7)  ·  Fondazione Policlinico Universitario Agostino Gemelli IRCCS (6)  ·  National Institute of Allergy and Infectious Diseases (NIAID) (5)  ·  National Allergy Research Center, Denmark (4)  ·  National Eye Institute (NEI) (4)  ·  University of Aarhus (4)  ·  Yale University (4)  ·  Allerderm (3)  ·  Duke University (3)  ·  Massachusetts Eye and Ear Infirmary (3)

Countries

United States (167)  ·  France (36)  ·  United Kingdom (34)  ·  Netherlands (26)  ·  Denmark (21)  ·  Germany (20)  ·  Canada (16)  ·  India (16)  ·  Italy (14)  ·  Belgium (11)  ·  Turkey (Türkiye) (10)  ·  China (9)  ·  Poland (8)  ·  Brazil (7)  ·  Japan (7)

Top investigators

Robert P Baughman, MD (11)  ·  Marc A Judson, MD (4)  ·  Aalt Bast, PhD (3)  ·  Agnes W Boots, PhD (3)  ·  Aliaa Barakat, PhD (3)  ·  Michael Iannuzzi (3)  ·  Rocco Trisolini, MD (3)  ·  Andrew M Wilson, MD (2)  ·  David Birnie, MD (2)  ·  Don C Rockey, MD (2)  ·  Elliott Crouser, MD (2)

Results publications

PMID 26179009, PMID 28775245, PMID 32176248, PMID 37459086, PMID 10228757, PMID 10767258, PMID 11451823, PMID 12045054, PMID 12558848, PMID 12894072, PMID 13148192, PMID 14899212, PMID 15161841, PMID 15225842, PMID 15287367, PMID 15618580, PMID 15824529, PMID 15855973, PMID 16100180, PMID 16315784, PMID 16840744, PMID 17099029, PMID 17346444, PMID 17426205, PMID 17643700, PMID 18256069, PMID 18263672, PMID 18494054, PMID 19117242, PMID 19188547, PMID 19395578, PMID 19786468, PMID 19884472, PMID 19897553, PMID 20013165, PMID 20298335, PMID 20560291, PMID 20706632, PMID 20843983, PMID 20926833, PMID 21030491, PMID 21039407, PMID 21086905, PMID 21299803, PMID 21324570, PMID 21420083, PMID 21436356, PMID 21482866, PMID 21629130, PMID 21732228

NIH funding

2017 (3), 2023 (3), 2014 (2), 1UM1HL113115-01A1 (1), 2009 (1), 2015 (1), 2018 (1), 2019 (1), 2025 (1), 5UL1RR024979 (1), K23HL148527 (1), K23MD017284 (1), R01HL054306 (1), R01HL117074 (1), R01HL157533 (1)