2 completed, 2 unknown, 1 enrolling by invitation, 1 not yet recruiting. 2 Not applicable, 1 Early Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Completed 1, Unknown 1 |
| Early Phase 1 | 1 | Enrolling by invitation 1 |
| Phase 2 | 1 | Not yet recruiting 1 |
Follow Drug Hypersensitivity Syndrome: new trials by email Literature Review of Drug Hypersensitivity Syndrome trials Research Report on Drug Hypersensitivity Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Interest of a Targeted Therapy for the Treatment of a Severe Form of Hypersensitivity to Drug (DRESS Syndrome) Benralizumab 30 MG/ML [Fasenra], Placebo Comparator: Placebo-Control Arm 0.9% Sodium Chloride - DRESS Syndrome | Phase 2 | Not yet recruiting | University Hospital, Lille | 96 | 2027-01-06 | 2026-05-15 |
| Cyclosporine Vs Steroids in DRESS Cyclosporine, Methylprednisolone and Prednisone - DRESS Syndrome, Drug-Induced Hypersensitivity Syndrome | Early Phase 1 | Enrolling by invitation | University of Southern California | 50 | 2021-09-27 | 2025-03-30 |
| Vitamin D Levels in Non-immediate Drug Hypersensitivity Case-control Study Stevens-Johnson Syndrome, Drug Reaction With Eosinophilia and Systemic Symptom | Completed | Chulalongkorn University | 120 | 2021-05-30 | 2024-02-16 | |
| Origin and Function of Eosinophilic Polynuclear During DRESS Syndrome Drug Hypersensitivity, DRESS Syndrome | Recruiting | University Hospital, Lille | 80 | 2020-07-15 | 2026-04-22 | |
| Severe Cutaneous Adverse Reactions in Thailand Steven-Johnson Syndrome, Toxic Epidermal Necrolysis | Unknown | Chulalongkorn University | 200 | 2014-01-01 | 2019-02-18 | |
| Comparison Between Corticosteroid and Topical Steroids in the DRESS Prednisone, Clobetasol - Drug Rash With Eosinophilia and Systemic Symptoms | Not applicable | Unknown | Assistance Publique - Hôpitaux de Paris | 112 | 2013-10-01 | 2015-07-30 |
| Immunological and Viral Parameters in Patients Receiving Anti-epileptic Drugs anti-epileptic drug, Blood sampling - Epilepsy, Drug Hypersensitivity Syndrome | Not applicable | Completed | University Hospital, Rouen | 30 | 2013-05-01 | 2016-01-25 |
Drug Hypersensitivity (4) · Stevens-Johnson Syndrome (2) · Acute Generalized Exanthematous Pustulosis (1) · Drug Eruptions (1) · Drug-Related Side Effects and Adverse Reactions (1) · Epilepsy (1) · Hypersensitivity (1) · Vitamin D Deficiency (1)
Chemically-Induced Disorders (7) · Dermatitis (7) · Hypersensitivity, Delayed (7) · Immune System Diseases (7) · Skin Diseases (7) · Skin and Connective Tissue Diseases (7) · Drug Eruptions (6) · Drug-Related Side Effects and Adverse Reactions (6) · Hypersensitivity (6) · Drug Hypersensitivity (3) · Erythema (2) · Erythema Multiforme (2) · Mouth Diseases (2) · Skin Diseases, Vesiculobullous (2) · Stomatitis (2)
Prednisone (2) · Anticonvulsants (1) · Blood Specimen Collection (1) · Clobetasol (1) · Cyclosporine (1) · Methylprednisolone (1) · Sodium Chloride (1) · benralizumab (1)
Chulalongkorn University (2) · University Hospital, Lille (2) · Assistance Publique - Hôpitaux de Paris (1) · University Hospital, Rouen (1) · University of Southern California (1)
France (4) · Thailand (2) · United States (1)
Delphine Staumont-Salle, MD,PhD (1) · Jettanong Klaewsongkram, MD (1)
PMID 25592341, PMID 27106261, PMID 29478292, PMID 29800753, PMID 30346532, PMID 34734507, PMID 37678574, PMID 38754628