7 completed, 3 terminated, 2 unknown. 12 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 12 | Completed 7, Terminated 3, Unknown 2 |
| Phase 2 | 3 | Completed 2, Terminated 1 |
Follow Diverticulitis: new trials by email Literature Review of Diverticulitis trials Research Report on Diverticulitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Rifaximin Delayed Release for the Prevention of Recurrent Acute Diverticulitis and Diverticular Complications. Rifaximin delayed released 400mg Tablet, Placebo - Diverticulitis | Phase 2 / Phase 3 | Terminated | Alfasigma S.p.A. | 193 | 2018-07-02 | 2021-10-20 |
| Effect of a Probiotic on Diverticular Symptoms Probiotic - Diverticular Disease | Phase 3 | Completed | King's College Hospital NHS Trust | 143 | 2013-04-01 | 2016-06-09 |
| Informativeness to Digital Rectal Examination lateral decubitus, supine decubitus - Colon Cancer, Upper Rectum Cancer | Phase 3 | Completed | Centre Hospitalier Universitaire, Amiens | 320 | 2012-11-01 | 2025-09-19 |
| Laparoscopic Peritoneal Lavage or Resection for Generalised Peritonitis for Perforated Diverticulitis Laparoscopic lavage and drainage, Sigmoidectomy with primary anastomosis, Sigmoidectomy with end-colostomy - Perforated Diverticulitis | Phase 3 | Unknown | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 283 | 2010-04-01 | 2014-03-21 |
| Two Doses Mesalazine Granules Versus Placebo for the Prevention of Recurrence of Diverticulitis Mesalazine, Placebo - Diverticulitis | Phase 3 | Terminated | Dr. Falk Pharma GmbH | 330 | 2010-01-01 | 2017-07-21 |
| Role Of Lactobacillus Reuteri DSM 17938 In The Non-Complicated Diverticular Disease Lactobacillus Reuterii, placebo - Diverticulosis, Diverticulitis | Phase 3 | Unknown | Casa Sollievo della Sofferenza IRCCS | 160 | 2009-02-01 | 2011-06-28 |
| Mesalazine Granules vs. Placebo for the Prevention of Recurrence of Diverticulitis Mesalazine, Placebo - Diverticulitis | Phase 3 | Terminated | Dr. Falk Pharma GmbH | 345 | 2008-01-01 | 2017-07-24 |
| Prevention of Recurrence of Diverticulitis SPD476, MMX™ mesalazine, 1.2g extended release tablet, SPD476, MMX™ mesalazine, 2.4g extended release tablet, SPD476, MMX™ mesalazine, 4.8g extended release tablet - Diverticulitis | Phase 3 | Completed | Shire | 592 | 2007-12-06 | 2021-06-11 |
| Prevention of Recurrence of Diverticulitis SPD476 (1.2g), SPD476 (2.4 g), SPD476 (4.8 g) - Diverticulitis | Phase 3 | Completed | Shire | 590 | 2007-11-28 | 2021-06-14 |
| An Assessment of Goal-Directed Intraoperative Fluid Management in Hand Assisted Laparoscopic Colectomy Hextend, Lactated Ringers - Crohn's Disease, Ulcerative Colitis | Phase 3 | Completed | Corewell Health West | 69 | 2007-05-01 | 2009-10-21 |
| Hartmann's Versus Primary Anastomosis in Left-sided Colon Perforation Hartmann's operation, Primary anastomosis - Surgery, Diverticulitis | Phase 2 / Phase 3 | Completed | University of Zurich | 62 | 2006-05-01 | 2012-05-28 |
| Hartmann vs R/A in Peritonitis by Perforated Diverticulitis Primary sigmoid resection with end colostomy (Hartmann), Primary sigmoid resection and immediate anastomosis with diverting stoma (PRA) - Peritonitis Caused by Perforated Left-sided Colon Diverticulitis | Phase 2 / Phase 3 | Completed | Ente Ospedaliero Ospedali Galliera | 100 | 2000-01-01 | 2010-11-15 |
Colonic Neoplasms (2) · Diverticular Diseases (2) · Diverticulum (2) · Rectal Neoplasms (2) · Colitis, Ulcerative (1) · Colonic Polyps (1) · Colorectal Neoplasms (1) · Crohn Disease (1) · Gastrointestinal Hemorrhage (1) · Hernia (1) · Intestinal Perforation (1) · Neoplasms (1) · Postoperative Complications (1)
Digestive System Diseases (12) · Gastroenteritis (12) · Gastrointestinal Diseases (12) · Diverticular Diseases (10) · Pathological Conditions, Signs and Symptoms (5) · Pathological Conditions, Anatomical (4) · Intestinal Diseases (3) · Colonic Diseases (2) · Digestive System Neoplasms (2) · Gastrointestinal Neoplasms (2) · Intestinal Neoplasms (2) · Neoplasms (2) · Neoplasms by Site (2) · Pathologic Processes (2) · Rectal Diseases (2)
Mesalamine (4) · Colectomy (1) · Drainage (1) · Hydroxyethyl Starch Derivatives (1) · Probiotics (1) · Ringer's Lactate (1) · Tablets (1)
Dr. Falk Pharma GmbH (2) · Shire (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Alfasigma S.p.A. (1) · Casa Sollievo della Sofferenza IRCCS (1) · Centre Hospitalier Universitaire, Amiens (1) · Corewell Health West (1) · Ente Ospedaliero Ospedali Galliera (1) · King's College Hospital NHS Trust (1) · University of Zurich (1)
Italy (4) · United States (4) · France (3) · Germany (3) · Netherlands (3) · United Kingdom (3) · Spain (2) · Argentina (1) · Australia (1) · Belgium (1) · Brazil (1) · Canada (1) · Colombia (1) · Finland (1) · Hungary (1)
Wolfgang Kruis, Professor (2) · Alberto Serventi (1) · Anthony Senagore, MD (1) · Gian Andrea Binda (1) · Ingvar Bjarnason, MD, MSc (1) · J.F. Lange, Professor (1) · Roberto Bergamaschi, MD (1) · Savvas Papagrigoriadis, MD, MSc (1) · Stefan Breitenstein, MD (1) · W.A. Bemelman, Professor (1)
PMID 25038431, PMID 28543263, PMID 28707787, PMID 28707796, PMID 23095627, PMID 25245464, PMID 26209030, PMID 31178342, PMID 35606544
2009 (1), 2017 (1)