13 recruiting, 3 not yet recruiting, 2 enrolling by invitation, 2 unknown. 6 Phase 1, 3 Not applicable, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Recruiting 5, Unknown 1 |
| Not applicable | 3 | Enrolling by invitation 1, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 3 | Recruiting 3 |
Follow Dilated Cardiomyopathy (DCM): new trials by email Literature Review of Dilated Cardiomyopathy (DCM) trials Research Report on Dilated Cardiomyopathy (DCM)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| BAG3-DCM Natural History Study Dilated Cardiomyopathy (DCM), Cardiovascular Diseases | Not yet recruiting | Rocket Pharmaceuticals Inc. | 30 | 2026-12-01 | 2026-10-19 | |
| An AAV Gene Therapy Trial of AFTX-201 in Adults With BAG3-Associated Dilated Cardiomyopathy (DCM) AFTX-201 - Dilated Cardiomyopathy (DCM), BAG3 Mutation Associated Dilated Cardiomyopathy | Phase 1 / Phase 2 | Recruiting | Affinia Therapeutics | 22 | 2026-10-01 | 2026-10-28 |
| Safety and Efficacy of Second Infusion of FAP iCDC in End-stage Dilated Cardiomyopathy FAP immunosuppressive CAR-DC - Dilated Cardiomyopathy (DCM), Heart Failure | Phase 1 | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 5 | 2026-05-11 | 2026-07-02 |
| A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy RP-A701 is a recombinant viral vector composed of an AAV serotype rh.74 (AAVrh.74) capsid encapsulating the transgene, BCL2-associated Athanogene 3 (BAG3) - Dilated Cardiomyopathy (DCM) | Phase 1 | Recruiting | Rocket Pharmaceuticals Inc. | 8 | 2026-04-17 | 2026-10-01 |
| Mainstreaming Genetic Testing for Non-Ischemic Cardiomyopathy in Western Canada Health service delivery change - Nonischemic Cardiomyopathy, Dilated Cardiomyopathy (DCM) | Not applicable | Enrolling by invitation | Thomas Roston | 300 | 2026-02-02 | 2026-05-08 |
| Endocardial Delivery for Myocardial Regeneration Using Allogeneic iPSC-derived Cardiomyocyte Spheroids for HF With Systolic Dysfunction (EMERALD Study) HS-005 - Heart Failure, Ischemic Heart Failure | Phase 1 / Phase 2 | Recruiting | Heartseed Inc. | 14 | 2026-01-19 | 2026-10-22 |
| Prognostic Values of Coronary Microvascular Dysfunction in Patients With Dilated Cardiomyopathy coronary angiography - Dilated Cardiomyopathy (DCM) | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 330 | 2026-01-06 | 2025-12-19 | |
| Study of the Progression of Chronic Cardiovascular Conditions Cardiovascular Disease (CVD), Heart Failure | Recruiting | Prolaio | 5000 | 2025-10-30 | 2026-08-12 | |
| Multimodal Analysis of Endomyocardial Biopsies Heart Transplantation, Dilated Cardiomyopathy (DCM) | Recruiting | University Hospital, Essen | 216 | 2025-10-27 | 2026-01-22 | |
| Protein A Immunoadsorption in Dilated Cardiomyopathy (RPIA-DCM) Immunoadsorption - Dilated Cardiomyopathy (DCM) | Not applicable | Recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 60 | 2025-06-04 | 2025-06-04 |
| Safety and Efficacy of FAP iCDC in End-stage Dilated Cardiomyopathy FAP immunosuppressive CAR-DC - Dilated Cardiomyopathy (DCM), Heart Failure | Phase 1 / Phase 2 | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 43 | 2025-04-22 | 2026-07-14 |
| Early Identification and Treatment of Rare Cardiomyopathy Cohorts diuretics, ACEIs/ARBs, beta blockers, positive inotropic drugs, MRAs, SGLT2i, retinoids, Close follow-up, early rehabilitation guidance - Hypertrophic Cardiomyopathy (HCM), Dilated Cardiomyopathy (DCM) | Not applicable | Not yet recruiting | RenJi Hospital | 300 | 2025-02-01 | 2025-01-27 |
| AI-enabled Screening and Diagnosis of Cardiomyopathies Using Coronary CTA CCTAI model - Cardiovascular Diseases, Hypertrophic Cardiomyopathy (HCM) | Not yet recruiting | Shanghai Zhongshan Hospital | 5000 | 2024-12-30 | 2024-12-27 | |
| Evaluating the Prognostic Impact of Anti-β1AR Antibodies and Anti-L-CaC Antibodies in Patients With Dilated Cardiomyopathy Dilated Cardiomyopathy (DCM) | Recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 1000 | 2024-12-17 | 2025-04-11 | |
| UIC Multi-Ethnic DCM Registry Heart Failure, Dilated Cardiomyopathy (DCM) | Recruiting | University of Illinois at Chicago | 1500 | 2024-07-11 | 2025-08-28 | |
| The Application of T1 Mapping in Real-World Magnetic Resonance Imaging with Contrast - Myocardial Infarction (MI), Hypertrophic Cardiomyopathy (HCM) | Recruiting | Chinese Academy of Medical Sciences, Fuwai Hospital | 2000 | 2020-03-01 | 2026-01-21 | |
| Multimodal and Multidisciplinary Approach to Optimize Diagnostic, Prognostic, and Therapeutic Management of Patients with Non-ischemic Cardiomyopathies and Arrhythmogenic-inflammatory Phenotypes: a Multicenter, Observational, Retrospective and Prospective Registry Study. Support treatment, cardiac medical treatment, aetiology-specific treatment, device implant, arrhythmia ablation, Support treatment, cardiac medical treatment, aetiology-specific treatment - Non-ischemic Cardiomyopathy, Dilated Cardiomyopathy (DCM) | Recruiting | Scientific Institute San Raffaele | 15000 | 2018-01-30 | 2024-09-23 | |
| Dilated cardiomYopathy iNtervention With Allogeneic MyocardIally-regenerative Cells (DYNAMIC) Allogeneic Cardiosphere-Derived Cells (CDCs) - Dilated Cardiomyopathy (DCM), Ischemic Cardiomyopathy | Phase 1 | Unknown | Capricor Inc. | 42 | 2014-11-01 | 2016-06-21 |
| Derivation of Human Induced Pluripotent Stem (iPS) Cells to Heritable Cardiac Arrhythmias Inherited Cardiac Arrythmias, Long QT Syndrome (LQTS) | Enrolling by invitation | Johns Hopkins University | 100 | 2013-08-01 | 2026-01-16 | |
| The Genetics of Dilated Cardiomyopathy: A Quebec-Based Study blood test - Dilated Cardiomyopathy (DCM) | Unknown | McGill University Health Centre/Research Institute of the McGill University Health Centre | 200 | 2008-01-01 | 2008-03-19 |
Cardiomyopathy, Dilated (20) · Cardiomyopathy, Hypertrophic (7) · Heart Failure (7) · Cardiomyopathies (5) · Cardiovascular Diseases (5) · Myocarditis (4) · Arrhythmogenic Right Ventricular Dysplasia (3) · Cardiomyopathy, Restrictive (3) · Heart Diseases (3) · Amyloid Neuropathies, Familial (2) · Aortic Valve Stenosis (1) · Brugada Syndrome (1) · Channelopathies (1) · Death, Sudden, Cardiac (1) · Dilatation, Pathologic (1)
Cardiomegaly (20) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (20) · Laminopathies (20) · Genetic Diseases, Inborn (19) · Heart Diseases (17) · Cardiomyopathies (15) · Cardiovascular Diseases (15) · Aortic Stenosis, Subvalvular (7) · Aortic Valve Disease (7) · Heart Valve Diseases (7) · Aortic Valve Stenosis (6) · Pathological Conditions, Signs and Symptoms (6) · Nervous System Diseases (4) · Pathologic Processes (4) · Vascular Diseases (4)
Adrenergic beta-Antagonists (1) · Diuretics (1) · Drug Therapy (1) · Equipment and Supplies (1) · Hematologic Tests (1) · MRAS protein, human (1) · Magnetic Resonance Imaging (1) · Plasmapheresis (1) · Retinoids (1)
Second Affiliated Hospital, Zhejiang University, School of Medicine (3) · Rocket Pharmaceuticals Inc. (2) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (2) · Affinia Therapeutics (1) · Capricor Inc. (1) · Chinese Academy of Medical Sciences, Fuwai Hospital (1) · Heartseed Inc. (1) · Johns Hopkins University (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1) · Prolaio (1) · RenJi Hospital (1) · Scientific Institute San Raffaele (1) · Shanghai Zhongshan Hospital (1) · Thomas Roston (1) · University Hospital, Essen (1)
China (7) · United States (6) · Canada (3) · Germany (1) · Italy (1) · Japan (1)
Xinyang Hu, PhD (2) · Andreas Barth, MD (1) · Chenguang Li, MD, PhD (1) · Deborah Ascheim, MD (1) · Jamie Engert, PhD (1) · Lars Michel, PD Dr. med. (1) · Meng Jiang, MD, PhD (1) · Nadia S Giannetti, MD (1) · Paolo Della Bella, MD (1) · Thomas Roston, MD/PhD (1) · Xiang Cheng, M.D., Ph.D. (1)
R01HL128743 (1), R44HL095203 (1)