5 recruiting, 1 unknown. 6 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Recruiting 5, Unknown 1 |
| Phase 2 | 3 | Recruiting 3 |
Follow Dilated Cardiomyopathy (DCM): new trials by email Literature Review of Dilated Cardiomyopathy (DCM) trials Research Report on Dilated Cardiomyopathy (DCM)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| An AAV Gene Therapy Trial of AFTX-201 in Adults With BAG3-Associated Dilated Cardiomyopathy (DCM) AFTX-201 - Dilated Cardiomyopathy (DCM), BAG3 Mutation Associated Dilated Cardiomyopathy | Phase 1 / Phase 2 | Recruiting | Affinia Therapeutics | 22 | 2026-10-01 | 2026-10-28 |
| Safety and Efficacy of Second Infusion of FAP iCDC in End-stage Dilated Cardiomyopathy FAP immunosuppressive CAR-DC - Dilated Cardiomyopathy (DCM), Heart Failure | Phase 1 | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 5 | 2026-05-11 | 2026-07-02 |
| A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy RP-A701 is a recombinant viral vector composed of an AAV serotype rh.74 (AAVrh.74) capsid encapsulating the transgene, BCL2-associated Athanogene 3 (BAG3) - Dilated Cardiomyopathy (DCM) | Phase 1 | Recruiting | Rocket Pharmaceuticals Inc. | 8 | 2026-04-17 | 2026-10-01 |
| Endocardial Delivery for Myocardial Regeneration Using Allogeneic iPSC-derived Cardiomyocyte Spheroids for HF With Systolic Dysfunction (EMERALD Study) HS-005 - Heart Failure, Ischemic Heart Failure | Phase 1 / Phase 2 | Recruiting | Heartseed Inc. | 14 | 2026-01-19 | 2026-10-22 |
| Safety and Efficacy of FAP iCDC in End-stage Dilated Cardiomyopathy FAP immunosuppressive CAR-DC - Dilated Cardiomyopathy (DCM), Heart Failure | Phase 1 / Phase 2 | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 43 | 2025-04-22 | 2026-07-14 |
| Dilated cardiomYopathy iNtervention With Allogeneic MyocardIally-regenerative Cells (DYNAMIC) Allogeneic Cardiosphere-Derived Cells (CDCs) - Dilated Cardiomyopathy (DCM), Ischemic Cardiomyopathy | Phase 1 | Unknown | Capricor Inc. | 42 | 2014-11-01 | 2016-06-21 |
Cardiomyopathy, Dilated (6) · Heart Failure (5) · Cardiomyopathies (2) · Cardiovascular Diseases (2) · Heart Diseases (2) · Dilatation, Pathologic (1) · Myocardial Ischemia (1) · Pathologic Processes (1) · Ventricular Dysfunction (1)
Cardiomegaly (6) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Genetic Diseases, Inborn (6) · Laminopathies (6) · Cardiomyopathies (4) · Cardiovascular Diseases (4) · Heart Diseases (4) · Pathological Conditions, Signs and Symptoms (2) · Pathological Conditions, Anatomical (1) · Vascular Diseases (1)
Second Affiliated Hospital, Zhejiang University, School of Medicine (2) · Affinia Therapeutics (1) · Capricor Inc. (1) · Heartseed Inc. (1) · Rocket Pharmaceuticals Inc. (1)
United States (3) · China (2) · Canada (1) · Japan (1)
Xinyang Hu, PhD (2) · Deborah Ascheim, MD (1)
R44HL095203 (1)