1306 completed. 1306 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 1306 | Completed 1306 |
Follow Digestive System Diseases: new trials by email Literature Review of Digestive System Diseases trials Research Report on Digestive System Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intraperitoneal Hydrocortisone for Postoperative Pain and CRP Following Caesarean Section hydrocortisone, Nornal Saline - Postoperative Pain, Caesarean Section | Phase 4 | Completed | Raditsya Mada Gautama, MD | 50 | 2026-06-25 | 2026-10-23 |
| Vonoprazan-based Versus Esomeprazole-based Triple Therapy for Helicobacter Pylori Eradication vonoprazan-based triple therapy (VAL regimen), Esomeprazole-based triple therapy (EAL regimen) - Helicobacter Pylori Infection, Dyspepsia | Phase 4 | Completed | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 80 | 2026-04-15 | 2026-10-26 |
| Effect of Ondansetron on Patient Tolerance, Efficacy and Endoscopist Workload in Unsedated Endoscopy for Upper Gastrointestinal Bleeding intravenous ondansetron, Placebo - Esophagogastroduodenoscopy, Upper Gastrointestinal Bleeding (UGIB) | Phase 4 | Completed | Peking Union Medical College Hospital | 80 | 2026-02-16 | 2026-09-16 |
| Irrigation of Bupivacaine at the Surgical Bed for Postoperative Pain Relief After Laparoscopic Cholecystectomy for Acute Cholecystitis Bupivacaine 0.5%, Normal Saline 0.9% - Acute Cholecystitis, Postoperative Pain | Phase 4 | Completed | Ziauddin University | 64 | 2025-10-01 | 2026-10-01 |
| Efficacy and Safety of GTN vs. Nifedipine in Acute Anal Fissure: A Clinical Trial Glyceryl Trinitrate (GTN) 0.2% Ointment, Glyceryl Trinitrate (GTN) 0.4% Ointment, Nifedipine 0.2% Ointment - Acute Anal Fissure, Anal Pain | Phase 4 | Completed | Hafiz Muhammad Hamza | 110 | 2025-03-17 | 2025-05-14 |
| Evaluation of the Effectiveness of a Topical Medical Device in Wound Healing and Symptom Relief in the Postoperative Period of Open Excisional Hemorrhoidectomy (The Emor Study) Gel containing a Propionibacterium extract, Hyaluronic acid and silver sulfadiazine - Anus Diseases, Gastrointestinal Diseases | Phase 4 | Completed | University of Cagliari | 114 | 2025-03-04 | 2025-07-02 |
| Intubation Conditions During ERCP With Lidocaine Aerosol Plus Low-dose Cisatracurium or Conventional-dose Cisatracurium Cisatracurium 0.05 mg/kg IV, Cisatracurium 0.15 mg/kg IV, Lidocaine aerosol 2.4% topical - Intubation, Intratracheal | Phase 4 | Completed | Jiangang Song | 186 | 2025-01-17 | 2026-05-28 |
| Safety of Stopping Pancreatic Enzyme Replacement Therapy in Children With Improved Pancreatic Function After Highly Effective Modulator Therapy Discontinuation of Pancreatic Enzyme Replacement Therapy - Cystic Fibrosis (CF), Pancreatic Insufficiency | Phase 4 | Completed | Indiana University | 17 | 2024-12-03 | 2026-07-02 |
| A Trial for Comparing Rifaximin, Probiotic and L-ornithine- L Aspartate With Lactulose in Overt Hepatic Encephalopathy. Probiotic plus lactulose, Rifaximin plus lactulose, L-ornithine-L-aspartate plus latulose - Overt Hepatic Encephalopathy | Phase 4 | Completed | Qurratul Ain Jamil | 252 | 2024-12-02 | 2025-06-25 |
| Helicobacter Pylori Screening and Treatment in the At-risk South Florida Community-AIM 2 PYTEST® 14C-Urea Capsule Breath Test (at Home), PYTEST® 14C-Urea Capsule Breath Test (Standard Retesting In-Person) - H. Pylori Infection, Gastric Cancer | Phase 4 | Completed | University of Miami | 50 | 2024-11-06 | 2026-10-16 |
| Evaluation of Efficacy of Skål Pro Powder on Symptoms of Irritable Bowel Syndrome Skal Pro, Placebo - Irritable Bowel Syndrome, Gastrointestinal Diseases | Phase 4 | Completed | EP Plus Group Sdn Bhd | 57 | 2024-10-17 | 2026-09-11 |
| Therapeutic Effect of Vonoprazan Versus Dexlansoprazole in Treatment of Gastroesophageal Reflux Disease Dexlansoprazole 60 mg, Vonoprazan 20 mg bid - Vonoprazan, Proton Pump Inhibitor | Phase 4 | Completed | Ayman Magd Eldin Mohammad Sadek | 136 | 2024-10-01 | 2025-02-27 |
| Enhanced Recovery After Surgery-Based Multimodal Preemptive Analgesia for Perioperative Management in Transarterial Chemoembolization of Intermediate-to-Advanced Hepatocellular Carcinoma hydrochloride hydromorphone + flurbiprofen axetil, conventional analgesia - Enhanced Recovery After Surgery, Multimodal Analgesia | Phase 4 | Completed | First Affiliated Hospital, Sun Yat-Sen University | 129 | 2024-08-01 | 2026-01-02 |
| Evaluation the of Role of Vitamin D Supplement on Tumor Response, Inflammation and Apoptosis in Patients With Stage II or III Colorectal Cancer Receiving Chemotherapy. Vitamin D - Vitamin D on Tumor Response and Inflammatory Markers, Colo-rectal Cancer | Phase 4 | Completed | Tanta University | 44 | 2024-07-31 | 2025-11-21 |
| Holding vs. Continuing Incretin-based Therapies Before Upper Endoscopy GLP-1 medication - Diabetes Mellitus, Type 2, Obesity | Phase 4 | Completed | The Cleveland Clinic | 69 | 2024-07-31 | 2025-12-05 |
| Association Between Effectiveness of Mirikizumab and UC Patients With High Neutrophilic Infiltration in Epithelium of the Colonic Mucosa Mirikizumab, Vedolizumab - Ulcerative Colitis | Phase 4 | Completed | Showa Inan General Hospital | 100 | 2024-07-20 | 2025-10-20 |
| Bowel Preparation in Colonoscopy: Lactulose vs Polyethyleneglycol, Randomized Double-blind Comparative Clinical Trial, Multicenter Study. Bowel preparation before colonoscopy - Colorectal Cancer Screening | Phase 4 | Completed | Hospital Civil de Guadalajara | 449 | 2024-07-20 | 2026-07-28 |
| Effect of Bioflor on Gut Microbiota in Proton-Pump Inhibitor Users Saccharomyces Boulardii 250 MG, Proton Pump Inhibitors (PPI) - Dysbiosis, Gastroesophageal Reflux Disease (GERD) | Phase 4 | Completed | Seoul National University Hospital | 80 | 2024-07-18 | 2026-10-01 |
| Postoperative Pain After Instillation Of Bupivacaine During Laparoscopic Cholecystectomy Bupivacain (Postoperative), Normal (0.9%) saline - Laparoscopic Cholecystectomy, Post Operative Analgesia | Phase 4 | Completed | Recep Tayyip Erdogan Hospital Pakistan - Muzaffargarh | 60 | 2024-07-11 | 2025-08-01 |
| Dose Optimization of Sitagliptin and Duloxetine in Diabetic Cirrhosis Sitagliptin (Januvia), Sitagliptin (JANUVIA®), Duloxetine (60 mg) once daily - Liver Cirrhosis With Diabetes | Phase 4 | Completed | Kafrelsheikh University | 64 | 2024-07-01 | 2026-02-27 |
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