5 completed, 2 unknown, 1 not yet recruiting, 1 terminated. 9 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 9 | Completed 5, Unknown 2, Not yet recruiting 1, Terminated 1 |
| Phase 2 | 3 | Completed 2, Not yet recruiting 1 |
Follow Diabetic Polyneuropathy: new trials by email Literature Review of Diabetic Polyneuropathy trials Research Report on Diabetic Polyneuropathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Oral DLBS1033 in Patients With Diabetic Polyneuropathy DLBS1033, Placebo Comparator: Placebo + Standard Therapy - Diabetic Polyneuropathy, Peripheral Nervous System Diseases | Phase 2 / Phase 3 | Not yet recruiting | Universitas Sebelas Maret | 34 | 2026-03-01 | 2026-03-16 |
| Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Diabetic Polyneuropathy Adezunap (AP707), Placebo - Pain, Pain Syndrome | Phase 3 | Unknown | Apurano Pharmaceuticals GmbH | 558 | 2023-11-02 | 2024-01-31 |
| Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Diabetic Polyneuropathy Adezunap (AP707), Placebo - Pain, Pain Syndrome | Phase 3 | Unknown | Apurano Pharmaceuticals GmbH | 558 | 2023-11-02 | 2024-01-31 |
| Dietetic and Hygiene Measures in Metabolic Neuropathies: the Neurodiet Study hygienic-dietetic measures - Peripheral Nervous System Diseases, Diabetic Polyneuropathy | Phase 3 | Completed | Henri Mondor University Hospital | 8 | 2011-11-01 | 2018-08-29 |
| A Long-term Safety Study With Tapentadol ER and Oxycodone CR in Patients With Moderate to Severe Pain Due to Chronic, Painful Diabetic Peripheral Neuropathy (DPN) Tapentadol extended release (ER), Oxycodone controlled release (CR) - Diabetic Neuropathy, Painful, Diabetic Polyneuropathy | Phase 3 | Terminated | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | 47 | 2010-01-01 | 2014-03-04 |
| Efficacy and Safety Study of Topical Capsaicin in Painful Diabetic Neuropathy Capsaicin, placebo - Diabetic Polyneuropathy | Phase 2 / Phase 3 | Completed | Thammasat University | 33 | 2009-10-01 | 2012-05-09 |
| Assessment of Efficacy and Safety of Thioctic Acid in the Oral Treatment of Symptomatic Diabetic Neuropathy (SYDNEY 2) Thioctic Acid - Diabetic Polyneuropathy | Phase 3 | Completed | MEDA Pharma GmbH & Co. KG | 170 | 2005-02-01 | 2022-02-07 |
| TempTouch IR Thermometry & Diabetic Patient Self-Care TempTouch® - Diabetic Polyneuropathy, Diabetic Foot Ulcer | Phase 2 / Phase 3 | Completed | Diabetica Solutions Inc. | 180 | 2000-06-01 | 2006-02-09 |
| Assessment of Efficacy and Safety of Thioctic Acid in the Oral Treatment of Diabetic Polyneuropathy (Stage 1 or 2) Thioctic Acid, Placebo - Diabetic Polyneuropathy | Phase 3 | Completed | MEDA Pharma GmbH & Co. KG | 460 | 1998-05-01 | 2022-02-07 |
Diabetic Neuropathies (9) · Peripheral Nervous System Diseases (5) · Diabetes Mellitus (4) · Pain (3) · Agnosia (2) · Chronic Pain (2) · Marijuana Abuse (2) · Somatoform Disorders (2) · Diabetic Foot (1) · Hereditary Sensory and Autonomic Neuropathies (1) · Metabolic Syndrome (1) · Neuralgia (1) · Polyneuropathies (1) · Ulcer (1)
Diabetes Complications (9) · Endocrine System Diseases (9) · Nervous System Diseases (9) · Neuromuscular Diseases (9) · Diabetes Mellitus (5) · Glucose Metabolism Disorders (5) · Metabolic Diseases (5) · Nutritional and Metabolic Diseases (5) · Pathological Conditions, Signs and Symptoms (5) · Neurologic Manifestations (4) · Peripheral Nervous System Diseases (4) · Signs and Symptoms (4) · Chemically-Induced Disorders (2) · Mental Disorders (2) · Neurobehavioral Manifestations (2)
Thioctic Acid (2) · Capsaicin (1) · DLBS 1033 (1) · Standard of Care (1) · lumbrokinase (1)
Apurano Pharmaceuticals GmbH (2) · MEDA Pharma GmbH & Co. KG (2) · Diabetica Solutions Inc. (1) · Henri Mondor University Hospital (1) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (1) · Thammasat University (1) · Universitas Sebelas Maret (1)
United States (3) · France (2) · Germany (2) · Croatia (1) · Denmark (1) · Indonesia (1) · Israel (1) · Italy (1) · Netherlands (1) · Russia (1) · Spain (1) · Sweden (1) · Thailand (1) · United Kingdom (1)
C. Mauli Agrawal, Ph.D. (1) · Dan Ziegler, Prof. (1) · Kevin R Higgins, DPM (1) · Kongkiat Kulkantrakorn, MD (1) · Krisandi Hartanto, MD (1) · Peter James Dyck (1)