6 completed, 3 unknown, 1 recruiting. 10 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Completed 6, Unknown 3, Recruiting 1 |
| Phase 2 | 4 | Completed 3, Recruiting 1 |
Follow Depressive Symptoms: new trials by email Literature Review of Depressive Symptoms trials Research Report on Depressive Symptoms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dog Presence and Oxytocin on Trust Towards Therapists Oxytocin nasal spray, Animal-Assisted Intervention, Placebo - Depressive Symptoms, Human-Animal Interaction | Phase 2 / Phase 3 | Recruiting | Dr. Karin Hediger | 176 | 2024-01-29 | 2024-11-05 |
| Acceptance Commitment Therapy for Caregivers of People with Memory Loss Acceptance and Commitment Therapy - Caregiver Burden, Behavioral and Psychiatric Symptoms of Dementia | Phase 3 | Completed | Utah State University | 121 | 2023-02-16 | 2024-12-06 |
| Transcendental Meditation and PTSD TM, PCT - Ptsd, Depressive Symptoms | Phase 3 | Unknown | David Lynch Foundation | 450 | 2021-10-01 | 2021-04-22 |
| Esketamine and Perioperative Depressive Symptoms Esketamine, Normal saline - Depressive Symptoms, Esketamine | Phase 2 / Phase 3 | Completed | Beijing Tiantan Hospital | 435 | 2021-02-19 | 2025-08-01 |
| Efficacy of Therapist Guided e-Therapy Versus Self-Help Therapy on Psychological Distress Among Individuals in Oman During COVID-19 Pandemic Therapist Guided E-Therapy, Self-Help Therapy - Depressive Symptoms, Generalized Anxiety | Phase 3 | Unknown | Sultan Qaboos University | 70 | 2020-06-01 | 2020-05-08 |
| Meru Health Ascend Mobile Intervention for Depression in Middle Aged and Older Adults Meru Health Ascend Program - Depression, Depressive Symptoms | Phase 2 / Phase 3 | Completed | Palo Alto Veterans Institute for Research | 70 | 2018-07-12 | 2021-03-10 |
| RCT of the Effectiveness of the WfWI Intervention in Afghanistan Women for Women International Intervention - Domestic Violence, Depressive Symptoms | Phase 3 | Unknown | Medical Research Council, South Africa | 1461 | 2016-10-01 | 2017-08-02 |
| The Efficacy, Safety, and Tolerability of Probiotics on the Mood and Cognition of Depressed Patients Probio'Stick - Major Depressive Disorder, Depression | Phase 3 | Completed | Queen's University | 10 | 2016-08-01 | 2019-06-14 |
| ICU Family Communication Study Facilitator-Based intervention, Usual Care - Depression, Depressive Symptoms | Phase 3 | Completed | University of Washington | 593 | 2008-06-01 | 2014-09-16 |
| Comparing Paroxetine and Duloxetine on Cardiovascular Measures paroxetine versus duloxetine - Depressive Symptoms | Phase 2 / Phase 3 | Completed | Duke University | 40 | 2005-03-01 | 2014-07-21 |
Depression (10) · Stress Disorders, Post-Traumatic (2) · Alcohol Drinking (1) · Anxiety Disorders (1) · Behavior (1) · Caregiver Burden (1) · Communication (1) · Depressive Disorder, Major (1) · Generalized Anxiety Disorder (1) · Human-Animal Interaction (1) · Sleep Initiation and Maintenance Disorders (1) · Suicidal Ideation (1)
Behavioral Symptoms (10) · Behavior (9) · Mental Disorders (5) · Stress Disorders, Traumatic (2) · Trauma and Stressor Related Disorders (2) · Anxiety Disorders (1) · Depressive Disorder (1) · Drinking Behavior (1) · Dyssomnias (1) · Mood Disorders (1) · Nervous System Diseases (1) · Self-Injurious Behavior (1) · Sleep Disorders, Intrinsic (1) · Sleep Wake Disorders (1) · Stress, Psychological (1)
Acceptance and Commitment Therapy (1) · Esketamine (1) · Saline Solution (1)
Beijing Tiantan Hospital (1) · David Lynch Foundation (1) · Dr. Karin Hediger (1) · Duke University (1) · Medical Research Council, South Africa (1) · Palo Alto Veterans Institute for Research (1) · Queen's University (1) · Sultan Qaboos University (1) · University of Washington (1) · Utah State University (1)
United States (4) · Canada (1) · China (1) · Switzerland (1)
Audrey C Juhasz, PhD (1) · Christine E Gould, PhD (1) · Elizabeth Fauth, PhD (1) · J. Randall Curtis, MD, MPH (1) · Rachel Jewkes, PhD (1) · Roumen Milev, PhD, MD (1) · Ruquan Han, M.D., Ph D. (1) · Ruth A Engelberg, PhD (1) · Thomas Rutledge, PhD (1) · Wei Zhang, M.D., Ph.D. (1)
PMID 26378963, PMID 29357843, PMID 29724222, PMID 31393873, PMID 32201622, PMID 33512323, PMID 35473735, PMID 42119799
2023 (1), R01NR005226 (1)