9 completed, 3 active not recruiting, 2 withdrawn, 1 recruiting. 17 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 17 | Completed 9, Active not recruiting 3, Withdrawn 2, Recruiting 1, Terminated 1, Unknown 1 |
Follow Degenerative Spondylolisthesis: new trials by email Literature Review of Degenerative Spondylolisthesis trials Research Report on Degenerative Spondylolisthesis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Restoring Segmental Lumbar Lordosis After Failed Previous Fusion at the Same Level Restoring segmental lordosis at the lumbar spine - Failed Back Surgery Syndrome, Degeneration Lumbar Spine | Not applicable | Active not recruiting | N.N. Priorov National Medical Research Center of Traumatology and Orthopedics | 20 | 2025-06-25 | 2026-07-02 |
| Mid- or High-flex Rods Versus Low-flex Rods of SpineShape System IV for Treatment of Degenerative Lumbar Spine Diseases SpineShape System IV straight rod elastic, SpineShape System IV straight rod medium, SpineShape System IV straight rod stiff - Degenerative Lumbar Spinal Stenosis, Facet Joint Arthrosis | Not applicable | Recruiting | SpineSave AG | 126 | 2024-06-04 | 2024-06-25 |
| Clinical Evaluation of Orion Lamina Cover in Patients Undergoing Lumbar Laminectomy With Instrumented Fusion Sham, ORION spinal lamina cover - Degenerative Lumbar Spinal Stenosis, Degenerative Spondylolisthesis | Not applicable | Completed | Orion Biotech Inc. | 30 | 2022-03-30 | 2024-08-01 |
| TLIF Osteo3 ZP Putty Study (Also Known as the TOP Fusion Study) Osteo3 ZP Putty - Degenerative Disc Disease, Degenerative Spondylolisthesis | Not applicable | Completed | OssDsign | 17 | 2021-09-07 | 2024-07-10 |
| Clinical Decision-Making and Virtual Reality Exercise VR skateboarding training - Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease | Not applicable | Completed | National Taiwan University Hospital | 200 | 2021-01-01 | 2025-06-22 |
| The Efficacy of Continuous Cold-Therapy on Postoperative Pain and Narcotics Use Following Spinal Fusion Cold-Therapy System - Radiculopathy, Central Spinal Stenosis | Not applicable | Withdrawn | Rush University Medical Center | 2020-04-01 | 2020-11-23 | |
| Clinical Outcomes Associated With the Use of ViviGen® for the Treatment of Lumbar Degenerative Disc Disease ViviGen® Cellular Bone Matrix with DePuy Synthes Spinal Pedicle screw system, Local Bone Autologous Bone Graft with DePuy Synthes Spinal pedicle screw system - Lumbar Spondylolisthesis, Degenerative Disc Disease | Not applicable | Completed | Corewell Health East | 46 | 2019-03-19 | 2025-06-26 |
| SLIP II Registry: Spinal Laminectomy Versus Instrumented Pedicle Screw Fusion Expert Panel Review - Lumbar Spondylolisthesis, Grade 1 Spondylolisthesis | Not applicable | Active not recruiting | Lahey Clinic | 662 | 2017-10-17 | 2026-10-21 |
| LimiFlex Clinical Trial for the Treatment of Degenerative Spondylolisthesis With Spinal Stenosis LimiFlex, Fusion Instrumentation, Decompression - Degenerative Spondylolisthesis, Lumbar Spinal Stenosis | Not applicable | Active not recruiting | Empirical Spine, Inc. | 299 | 2017-07-17 | 2025-08-07 |
| A Pivotal Study of the Premia Spine TOPS™ System Total Posterior Spine System (TOPS), Transforaminal Lumbar Interbody Fusion (TLIF) - Lumbar Spinal Stenosis, Degenerative Spondylolisthesis | Not applicable | Completed | Premia Spine | 305 | 2017-07-17 | 2024-06-17 |
| Unilateral Versus Bilateral TLIF for Degenerative Lumbar Spondylolisthesis Unilateral Transforaminal Interbody fusion, Bilateral Transforaminal Interbody fusion - Degenerative Spondylolisthesis, Transforaminal Lumbar Interbody Fusion | Not applicable | Unknown | Kyungpook National University Hospital | 52 | 2017-07-06 | 2019-02-27 |
| "Is Instrumentation Necessary for "Static" Degenerative Spondylolisthesis" instrumented spinal fusion with laminectomy, non-instrumented spinal fusion with laminectomy - Degenerative Spondylolisthesis, Spinal Stenosis | Not applicable | Withdrawn | University of Pittsburgh | 2015-10-01 | 2015-12-16 | |
| Lumbar Stabilization Exercises vs Flexor Exercises in Degenerative Spondylolisthesis Lumbar stabilization exercises, Flexor exercises - Degenerative Spondylolisthesis, Chronic Low Back Pain | Not applicable | Completed | Instituto Nacional de Rehabilitacion | 92 | 2015-07-01 | 2019-03-19 |
| Dynesys Spinal System Post Market 522 Study Dynesys Spinal System - Degenerative Spondylolisthesis, Pseudoarthrosis | Not applicable | Terminated | Zimmer Biomet | 153 | 2012-03-01 | 2020-01-29 |
| Valeo OL Interbody Fusion Devices for Posterior Lumbar Interbody Fusion SNAP Trial Posterior lumbar interbody fusion with a PEEK cage, Posterior lumbar interbody fusion with a Valeo OL cage - Disc Degeneration of Pfirrmann Grade III or Greater, Degenerative Spondylolisthesis | Not applicable | Completed | Amedica Corporation | 100 | 2012-02-01 | 2017-04-04 |
| SPONGIT: Comparison of Two Surgical Approaches in the Treatment of Degenerative Spondylolysthesis Circumferential arthrodesis, Posterolateral fusion with instrumentation - Degenerative Spondylolisthesis | Not applicable | Completed | University Hospital, Bordeaux | 60 | 2009-06-01 | 2026-05-14 |
| Multimodal Perioperative Pain Management Postoperative epidural morphine, Local anaesthesia - Degenerative Spondylolisthesis | Not applicable | Completed | Northern Orthopaedic Division, Denmark | 120 | 2001-01-01 | 2015-05-28 |
Spinal Stenosis (7) · Spondylolisthesis (7) · Intervertebral Disc Degeneration (5) · Radiculopathy (2) · Failed Back Surgery Syndrome (1) · Intervertebral disc disease (1) · Low Back Pain (1) · Pseudarthrosis (1) · Scoliosis (1) · Spinal Fractures (1) · Spondylarthritis (1)
Bone Diseases (15) · Musculoskeletal Diseases (15) · Spinal Diseases (15) · Spondylolysis (7) · Spondylosis (7) · Back Pain (2) · Fractures, Bone (2) · Nervous System Diseases (2) · Neurologic Manifestations (2) · Neuromuscular Diseases (2) · Pain (2) · Pathological Conditions, Signs and Symptoms (2) · Peripheral Nervous System Diseases (2) · Signs and Symptoms (2) · Wounds and Injuries (2)
Anesthesia, Local (1) · Decompression (1) · Gene Fusion (1) · Laminectomy (1)
Amedica Corporation (1) · Corewell Health East (1) · Empirical Spine, Inc. (1) · Instituto Nacional de Rehabilitacion (1) · Kyungpook National University Hospital (1) · Lahey Clinic (1) · N.N. Priorov National Medical Research Center of Traumatology and Orthopedics (1) · National Taiwan University Hospital (1) · Northern Orthopaedic Division, Denmark (1) · Orion Biotech Inc. (1) · OssDsign (1) · Premia Spine (1) · Rush University Medical Center (1) · SpineSave AG (1) · University Hospital, Bordeaux (1)
United States (5) · Taiwan (2) · Canada (1) · Denmark (1) · France (1) · Hungary (1) · Mexico (1) · Netherlands (1) · Russia (1) · South Korea (1) · Switzerland (1)
David S. Krum-Moeller, M.D. (1) · Henrik Kehlet, M.D. (1) · Jad G Khalil, MD (1) · Joel Batts (1) · Joon Y Lee, M.D. (1) · Kern Singh, MD (1) · Lene R. Lauridsen (1) · Peter P Varga, MD (1) · Philipp Cathrein, Dr.med. (1) · Rick Sasso, MD (1) · Sten Rasmussen, M.D. (1) · Wei-Li Hsu, Ph.D (1)
PMID 23948848, PMID 24568365, PMID 25238480, PMID 27548582, PMID 33792726, PMID 36152329, PMID 38974656, PMID 39868633, PMID 41196064