84 completed. 84 Phase 3, 17 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 84 | Completed 84 |
| Phase 2 | 17 | Completed 17 |
Follow Deficiency Diseases: new trials by email Literature Review of Deficiency Diseases trials Research Report on Deficiency Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Efficacy of 0.75% Phentolamine Ophthalmic Solution in Subjects With Post-refractive Surgery Visual Disturbances phentolamine ophthalmic solution 0.75%, a non-selective alpha-1 and alpha-2 adrenergic antagonist, Placebo - Mesopic Vision, Night Vision Loss | Phase 3 | Completed | Opus Genetics, Inc | 200 | 2024-04-01 | 2026-10-26 |
| Vitamin D, Oxidative Stress and Inflammation in Hemodialysis Cholecalciferol - Oxidative Stress, Inflammation | Phase 2 / Phase 3 | Completed | Ain Shams University | 25 | 2022-05-15 | 2023-02-06 |
| Cholecalciferol Supplementation in Hemodialysis Patients Cholecalciferol - Anemia, Hemodialysis Complication | Phase 2 / Phase 3 | Completed | Ain Shams University | 50 | 2022-05-15 | 2023-06-28 |
| Effectiveness of Vitamin C Supplementation in Treatment of Rickets Vit C - Nutritional Rickets, Bone Turnover Rate Disorder | Phase 2 / Phase 3 | Completed | Cairo University | 88 | 2022-03-01 | 2023-03-08 |
| Impact of Vitamin D3 Supplementation in Non-Sjogren Dry Eye Patients With Low Serum Vitamin D Level Vitamin D, Artificial tear - Dry Eye Syndromes, Hypovitaminosis D | Phase 3 | Completed | University of Faisalabad | 108 | 2021-11-01 | 2022-06-21 |
| Vitamin D Supplementation in Individuals With a Chronic Spinal Cord Injury Cholecalciferol (Vitamin D3), Placebo - Spinal Cord Injuries, Vitamin D Deficiency | Phase 3 | Completed | Swiss Paraplegic Research, Nottwil | 50 | 2021-05-19 | 2024-03-08 |
| Injection of Teriparatide to Prevent Hypocalcemia After Parathyroidectomy in Dialysis Patients (TeriCa). Teriparatide - Secondary Hyperparathyroidism, Chronic Kidney Disease-Mineral and Bone Disorder | Phase 3 | Completed | Saint Petersburg State University, Russia | 20 | 2021-03-01 | 2022-11-10 |
| Anti-FGF23 (Burosumab) in Adult Patients With XLH Burosumab - X-linked Hypophosphatemia | Phase 3 | Completed | Wuerzburg University Hospital | 36 | 2021-01-07 | 2023-05-03 |
| Efficacy and Safety of Calcifediol vs Placebo in Subjects With Vitamin D Deficiency Calcifediol 75mcg, Calcifediol 100mcg, Calcifediol 125mcg - Vitamin D Deficiency, Vitamin D Insufficiency | Phase 2 / Phase 3 | Completed | Faes Farma, S.A. | 674 | 2020-12-23 | 2023-09-15 |
| Vitamin D 24'000 IU for Oral Intermittent Supplementation Vitamin D3, Vitamin D oily capsules - Vitamin D Deficiency | Phase 3 | Completed | University Hospital, Basel, Switzerland | 58 | 2019-09-30 | 2020-06-04 |
| Rapid Normalization of Vitamin D Deficiency in PICU Cholecalciferol, Placebo - Vitamin D Deficiency | Phase 3 | Completed | Children's Hospital of Eastern Ontario | 424 | 2019-06-17 | 2025-02-12 |
| Study of the Anti-FGF23 Antibody, Burosumab, in Adults With XLH Burosumab - X-linked Hypophosphatemia | Phase 3 | Completed | Kyowa Kirin Pharmaceutical Development Ltd | 35 | 2019-03-07 | 2022-05-20 |
| High-Dose Vitamin D3 Supplementation in the Treatment of Human Immune Deficiency Virus Patients Trial placebo Oil, 25-Hydroxyvitamin D - HIV-1-infection, Hypovitaminosis D | Phase 3 | Completed | University of the Punjab | 95 | 2019-02-15 | 2022-04-11 |
| The Efficacy and the Safety of Vitamin D3 30,000 IU for Loading Dose Schedules Cholecalciferol - Vitamin D Deficiency | Phase 3 | Completed | Semmelweis University | 75 | 2018-09-05 | 2022-03-04 |
| Cholecalciferol on Hemodialysis Patients Cholecalciferol, Placebo - Hemodialysis Complication, Vitamin D Deficiency | Phase 2 / Phase 3 | Completed | Ain Shams University | 60 | 2018-07-01 | 2019-01-09 |
| Vitamine D in Drug Resistant Epilepsy Cholecalciferol, Placebo Oral - Drug Resistant Epilepsy | Phase 3 | Completed | Centre Hospitalier St Anne | 88 | 2018-04-03 | 2024-07-12 |
| Open Label Trial Assessing Safety and Efficacy of Burosumab (KRN23), in a Patient With ENS and Hypophosphatemic Rickets Burosumab - Hypophosphatemia, Hypophosphatemic Rickets | Phase 3 | Completed | Redwood Dermatology Sciences | 1 | 2018-01-31 | 2020-01-18 |
| Vitamin D Supplementation to Prevent Vitamin D Deficiency for Children With Epilepsy Vitamin D 3 - Epilepsy, Vitamin D Deficiency | Phase 3 | Completed | King Saud University | 116 | 2018-01-01 | 2021-09-13 |
| Importance of Dosing Regimen for the Effect of Vitamin D Supplementation Vitamin D, Placebo - Hypovitaminosis D | Phase 3 | Completed | University of Tromso | 61 | 2017-12-01 | 2018-05-24 |
| MAGnesium Adjunction in Alcohol Withdrawal Syndrome: a Multicenter Assessment (MAGMA) Magnesium, Placebo Oral Tablet - Alcohol Withdrawal Syndrome | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 105 | 2017-11-16 | 2021-12-21 |
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Vitamin D Deficiency (52) · Vitamin A Deficiency (8) · Familial Hypophosphatemic Rickets (7) · Renal Insufficiency, Chronic (6) · Kidney Diseases (5) · Rickets (5) · Critical Illness (4) · Hyperparathyroidism (4) · Hyperparathyroidism, Secondary (4) · Osteoporosis (4) · Renal Insufficiency (4) · Avitaminosis (3) · Hyperhomocysteinemia (3) · Inflammation (3) · Kidney Failure, Chronic (3)
Malnutrition (84) · Nutrition Disorders (84) · Nutritional and Metabolic Diseases (84) · Avitaminosis (77) · Metabolic Diseases (27) · Pathological Conditions, Signs and Symptoms (22) · Urogenital Diseases (22) · Female Urogenital Diseases and Pregnancy Complications (21) · Bone Diseases, Metabolic (18) · Female Urogenital Diseases (18) · Musculoskeletal Diseases (18) · Pathologic Processes (18) · Bone Diseases (17) · Calcium Metabolism Disorders (17)
Cholecalciferol (38) · Vitamin D (11) · burosumab (7) · Calcifediol (5) · Vitamin A (4) · Calcium Carbonate (3) · Sugars (3) · Alendronate (2) · Calcitriol (2) · Duration of Therapy (2) · Ergocalciferols (2) · paricalcitol (2) · 1 alpha-hydroxyergocalciferol (1) · 25-hydroxyvitamin D (1) · Calcium (1)
Johns Hopkins Bloomberg School of Public Health (4) · Ain Shams University (3) · Kyowa Kirin, Inc. (3) · Massachusetts General Hospital (3) · Medical University of South Carolina (3) · University of Tromso (3) · American University of Beirut Medical Center (2) · OPKO IP Holdings II, Inc. (2) · Semmelweis University (2) · Alexion Pharmaceuticals, Inc. (1) · Assistance Publique - Hôpitaux de Paris (1) · Association Tunisienne d'Etude & de Recherche sur l'Athérosclérose (1) · Cairo University (1) · Center for Health Sciences, Serbia (1) · Centre Hospitalier St Anne (1)
United States (32) · France (8) · Canada (6) · Japan (6) · United Kingdom (5) · Egypt (4) · Italy (4) · Bangladesh (3) · Germany (3) · Hungary (3) · Norway (3) · South Korea (3) · Spain (3) · Switzerland (3) · Australia (2)
Joel Melnick, MD (3) · Alfred Sommer, M.D. (2) · Amanda C Palmer, PhD (2) · Abdul Hakim Nattouf, MD, PhD (1) · Adekunle Dawodu, MBBS (1) · Alain B Labrique, MSc (1) · Alain B. Labrique, MSc (1) · Alain Labrique, PhD (1) · Albina Nowak, MD (1) · Anke Scheel-Sailer, Dr. med. (1) · Arezu Dezfuli, MD (1) · Ariel A. Salas, MD (1) · Benjamin U Nwosu, MD (1)
PMID 33305842, PMID 39151033, PMID 28490513, PMID 36854566, PMID 39077939, PMID 16973975, PMID 18625626, PMID 18689371, PMID 18697901, PMID 19386744, PMID 19776145, PMID 19829124, PMID 20141576, PMID 20237066, PMID 20435345, PMID 20719580, PMID 20941903, PMID 20977661, PMID 21197089, PMID 21510905, PMID 21586714, PMID 21628633, PMID 21706518, PMID 21791335, PMID 21832026, PMID 21857221, PMID 22071710, PMID 22077475, PMID 22218721, PMID 22412025, PMID 22467697, PMID 22784845, PMID 22790678, PMID 22955514, PMID 23151532, PMID 23256143, PMID 23559082, PMID 23719555, PMID 24290111, PMID 24455219, PMID 25005784, PMID 25029424, PMID 25268295, PMID 25527663, PMID 25646326, PMID 25872802, PMID 26201817, PMID 26416936, PMID 26529632, PMID 26725194
2014 (1), 2016 (1), 2018 (1), 2019 (1), K23DK087859 (1), P50AR054086 (1), R01AG019147 (1), R01HD043921 (1), R01HD047511 (1), R01HL069272 (1), R21DK078012 (1), U01HL123009 (1)