10 unknown. 10 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Unknown 10 |
| Phase 2 | 3 | Unknown 3 |
Follow cyclopia sequence: new trials by email Literature Review of cyclopia sequence trials Research Report on cyclopia sequence
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Noisome as A Carrier of Locally Delivered Minocycline Hydrochloride Gel Minocycline hydrochloride with noisome carrier, Minocycline Hydrochloride only - Periodontitis | Phase 2 / Phase 3 | Unknown | Ain Shams University | 30 | 2024-02-25 | 2024-02-12 |
| Minocycline Attenuate Postoperative Cognitive Dysfunction and Delirium Minocycline, Placebo - Prostate Cancer, Carcinoma of the Rectum | Phase 3 | Unknown | RenJi Hospital | 750 | 2016-11-01 | 2020-01-28 |
| Minocycline add-on to Antipsychotics for the Treatment of Negative and Cognitive Symptoms in Schizophrenia Minocycline, Placebo, Probiotics - Schizophrenia | Phase 3 | Unknown | Beer Yaakov - Ness Ziona Mental Health Center | 40 | 2015-01-01 | 2016-09-20 |
| Minocycline in Acute Spinal Cord Injury (MASC) Minocycline, Placebo, Surgical spinal cord decompression - Spinal Cord Injuries | Phase 3 | Unknown | Rick Hansen Institute | 248 | 2013-06-01 | 2014-10-30 |
| Prevention of Imminent Paralysis Following Spinal Cord Trauma or Ischemia by Minocycline: A Multi-center Study in Israel With IDF Primary Care Involvement Minocycline, placebo - Spinal Tumors, Trauma Patients, Minocycline. | Phase 2 / Phase 3 | Unknown | Hadassah Medical Organization | 444 | 2013-05-01 | 2013-03-18 |
| An Open Label Study of Oral Minocycline for the Treatment of Patients With Co-occurring Opioid and ATS Dependence Minocycline - Heroin Dependence, Amphetamine Dependence | Phase 3 | Unknown | Universiti Sains Malaysia | 40 | 2013-04-01 | 2015-09-04 |
| The Efficacy of Topical Minocycline in Managing Symptomatic Oral Lichen Planus Minocycline, Dexamethasone - Oral Lichen Planus | Phase 3 | Unknown | Sheba Medical Center | 30 | 2010-03-01 | 2010-03-09 |
| Intrapleural Minocycline After Simple Aspiration for the Prevention of Primary Spontaneous Pneumothorax Simple aspiration with minocycline pleurodesis, simple aspiration - Pneumothorax | Phase 3 | Unknown | National Taiwan University Hospital | 300 | 2006-11-01 | 2012-12-17 |
| Pleural Abrasion Plus Minocycline Versus Apical Pleurectomy for Primary Spontaneous Pneumothorax 1 apical pleurectomy, 2 pleural abrasion + minocycline pleurodesis - Pneumothorax | Phase 2 / Phase 3 | Unknown | National Taiwan University Hospital | 200 | 2005-04-01 | 2006-08-07 |
| Additional Minocycline Pleurodesis After Thoracoscopic Procedures for Primary Spontaneous Pneumothorax intrapleural minocycline instillation - Pneumothorax | Phase 3 | Unknown | National Taiwan University Hospital | 200 | 2001-06-01 | 2005-10-20 |
Pneumothorax (3) · Amphetamine-Related Disorders (1) · Carcinoma, Renal Cell (1) · Colonic Neoplasms (1) · Emergence Delirium (1) · Heroin Dependence (1) · Inflammation (1) · Lichen Planus, Oral (1) · Neurobehavioral Manifestations (1) · Periodontitis (1) · Postoperative Cognitive Complications (1) · Prostatic Neoplasms (1) · Rectal Neoplasms (1) · Schizophrenia (1)
Nervous System Diseases (4) · Mental Disorders (3) · Pleural Diseases (3) · Respiratory Tract Diseases (3) · Central Nervous System Diseases (2) · Mouth Diseases (2) · Neoplasms (2) · Neoplasms by Site (2) · Neurologic Manifestations (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Spinal Cord Diseases (2) · Stomatognathic Diseases (2) · Adenocarcinoma (1)
Minocycline (7) · Dexamethasone (1) · Probiotics (1)
National Taiwan University Hospital (3) · Ain Shams University (1) · Beer Yaakov - Ness Ziona Mental Health Center (1) · Hadassah Medical Organization (1) · RenJi Hospital (1) · Rick Hansen Institute (1) · Sheba Medical Center (1) · Universiti Sains Malaysia (1)
Taiwan (3) · Israel (2) · Australia (1) · Canada (1) · China (1) · Egypt (1) · Malaysia (1)
Yung-Chie Lee, MD, PhD (3) · Imran Ahmad, MBBS (1) · Jin-Shing Chen, MD, PhD (1) · Noam Yarom, DMD (1) · Rafael Stryjer, MD (1) · Steve Casha, MD PhD FRCSC (1) · Yasmin Fouad, PHD (1)