49 completed. 49 Phase 3, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 49 | Completed 49 |
| Phase 2 | 6 | Completed 6 |
Follow Cross Infection: new trials by email Literature Review of Cross Infection trials Research Report on Cross Infection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oro-nasal Decontamination to Prevent Ventilator-associated Pneumonia Povidone-Iodine, Saline spray - Ventilator Associated Pneumonia | Phase 2 / Phase 3 | Completed | Menoufia University | 78 | 2023-06-24 | 2023-11-27 |
| Daily Chlorexidine Bath for Health Care Associated Infection Prevention 2% chlorhexidine digluconate solution with surface-active agents, Usual Baths - Health Care Associated Infection, Ventilator Associated Pneumonia | Phase 3 | Completed | Hospital do Coracao | 15730 | 2022-08-03 | 2024-06-13 |
| Management of Ventilation Acquired Pneumonia Caused by Pseudomonas and Acinetobacter Organisms in a Pediatric Center extended meropenem infusion in combination with other options such as Polymyxin, Tigecycline, Ertapenem, or Amikacin., two β-lactam antibiotics plus a single non-β-lactam antibiotic, Control group received standard therapy - Ventilation Acquired Pneumonia | Phase 3 | Completed | Beni-Suef University | 64 | 2021-01-01 | 2024-12-18 |
| Adjunctive Therapy to Antibiotics in the Treatment of S. Aureus Ventilator-Associated Pneumonia With AR-301 AR-301, Placebo - Lung Infection, Pneumonia, Ventilator-Associated | Phase 3 | Completed | Aridis Pharmaceuticals, Inc. | 174 | 2019-05-03 | 2023-07-06 |
| A Study to Determine the Efficacy, Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI) ± Metronidazole (MTZ) Versus Meropenem (MER) ± Colistin (COL) for the Treatment of Serious Infections Due to Gram Negative Bacteria. ATM-AVI, MTZ, MER - Complicated Intra-abdominal Infection, Hosptial Acquired Pneumonia | Phase 3 | Completed | Pfizer | 422 | 2018-04-05 | 2024-12-10 |
| Defining Antibiotic Treatment Duration for Ventilator - Associated Lung Infection Reducing Antibiotics treatment duration, Standard Antibiotics treatment duration - Ventilator Associated Pneumonia, Pneumonia, Bacterial | Phase 3 | Completed | University of Oxford | 460 | 2018-02-21 | 2024-01-18 |
| Ceftobiprole in the Treatment of Pediatric Patients With Pneumonia ceftobiprole medocaril, IV standard-of-care cephalosporin - Community-acquired Pneumonia (CAP), Hospital-acquired Pneumonia (HAP) | Phase 3 | Completed | Basilea Pharmaceutica | 138 | 2017-11-27 | 2023-05-12 |
| Clinical Study of Cefiderocol (S-649266) for the Treatment of Nosocomial Pneumonia Caused by Gram-negative Pathogens Cefiderocol, Meropenem, Linezolid - Healthcare-associated Pneumonia (HCAP), Hospital Acquired Pneumonia (HAP) | Phase 3 | Completed | Shionogi | 300 | 2017-10-24 | 2020-11-13 |
| Study Comparing Inhaled Amikacin Versus Placebo to Prevent Ventilator Associated Pneumonia Inhaled amikacin, Inhaled placebo - Pneumonia, Ventilator-Associated | Phase 3 | Completed | University Hospital, Tours | 850 | 2017-07-19 | 2025-12-22 |
| Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients SDD Oral Paste, SDD Gastric Suspension, Intravenous Antibiotic - Critical Illness, Sepsis | Phase 3 | Completed | The George Institute | 20010 | 2017-05-01 | 2023-08-14 |
| Study of Cefiderocol (S-649266) or Best Available Therapy for the Treatment of Severe Infections Caused by Carbapenem-resistant Gram-negative Pathogens Cefiderocol, Best Available Therapy - Healthcare-associated Pneumonia (HCAP), Bloodstream Infections (BSI) | Phase 3 | Completed | Shionogi | 152 | 2016-09-07 | 2021-01-12 |
| The Effect of Colistin Inhalation on Ventilator Associated Pneumonia Colistin, Carbapenem + Aminoglycoside/ Quinolone - Ventilator Associated Pneumonia | Phase 2 / Phase 3 | Completed | Nourhan Hassan Osama Thuraya Mohamed | 40 | 2016-01-02 | 2018-08-09 |
| Safety and Efficacy Study of Ceftolozane/Tazobactam to Treat Ventilated Nosocomial Pneumonia (MK-7625A-008) Ceftolozane/tazobactam, Meropenem - Healthcare-Associated Pneumonia, Ventilator-Associated Pneumonia | Phase 3 | Completed | Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 726 | 2014-09-02 | 2020-05-05 |
| Antibiotherapy During Therapeutic Hypothermia to Prevent Infectious Complications Amoxicillin - clavulanic acid, Placebo - Ventilator-associated Pneumonia, Cardiac Arrests With Shockable Rhythm | Phase 3 | Completed | University Hospital, Limoges | 197 | 2014-08-18 | 2020-03-18 |
| Administration of a Lactobacillus GG and Vitamins Containing Mixture is Effective in Preventing Nosocomial Infection in Children Lactobacillus Rhamnosus GG, PLACEBO - Nosocomial Infection | Phase 3 | Completed | Federico II University | 90 | 2014-01-01 | 2015-09-23 |
| A Study Comparing Ceftazidime-Avibactam Versus Meropenem in Hospitalized Adults With Nosocomial Pneumonia ceftazidim-avibactam (CAZ-AVI, experimental product), meropenem (active comparator) - Nosocomial Pneumonia (NP), Ventilator-associated Pneumonia (VAP) | Phase 3 | Completed | Pfizer | 969 | 2013-04-01 | 2017-09-06 |
| A Phase III Study to Evaluate the Safety, Efficacy and Pharmacokinetics/Pharmacodynamics of BAYQ3939 in Patients With Bacterial Pneumonia Ciprofloxacin (Cipro, BAYQ3939) - Pneumonia | Phase 3 | Completed | Bayer | 44 | 2012-05-01 | 2015-04-27 |
| Duration of Antibiotic Therapy in the Treatment of Severe Postoperative Peritonitis Admitted in ICU Duration of antibiotic therapy limited to 8 days - Postoperative Peritonitis | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 244 | 2011-05-01 | 2015-12-09 |
| L Reuteri for the Prevention of Nosocomial Diarrhea Lactobacillus reuteri (DSM 17938) - Nosocomial Infection, Diarrhea | Phase 3 | Completed | Medical University of Warsaw | 106 | 2009-12-01 | 2012-01-31 |
| Efficacy and Safety of Ethanol Lock Solution in Prevention of Catheter Related Bloodstream Infection for Patients Suffering Acute Renal Failure, and Hospitalized in Intensive Care Unit. A Multi-Center, Randomized, Versus Placebo, Double Blinded Clinical Trial Ethanol - Acute Renal Failure, Infection | Phase 3 | Completed | University Hospital, Clermont-Ferrand | 1460 | 2009-04-01 | 2026-05-20 |
Showing 20 of 49. Sign in to see all of them.
Pneumonia, Ventilator-Associated (26) · Healthcare-Associated Pneumonia (13) · Pneumonia (11) · Pneumonia, Bacterial (5) · Sepsis (5) · Community-Acquired Infections (3) · Community-Acquired Pneumonia (3) · Infections (3) · Staphylococcal Infections (3) · Bacterial Infections (2) · Intraabdominal Infections (2) · Lung Diseases (2) · Respiratory Insufficiency (2) · Surgical Wound Infection (2)
Disease Attributes (49) · Iatrogenic Disease (49) · Pathologic Processes (49) · Pathological Conditions, Signs and Symptoms (49) · Infections (46) · Respiratory Tract Diseases (33) · Respiratory Tract Infections (33) · Lung Diseases (31) · Pneumonia (22) · Healthcare-Associated Pneumonia (18) · Bacterial Infections and Mycoses (9) · Bacterial Infections (7) · Inflammation (5) · Systemic Inflammatory Response Syndrome (5)
Tigecycline (5) · Linezolid (4) · Colistin (3) · Meropenem (3) · ceftobiprole (3) · Cefiderocol (2) · Ceftazidime (2) · Ciprofloxacin (2) · Doripenem (2) · Levofloxacin (2) · Vancomycin (2) · Amikacin (1) · Aminoglycosides (1) · Amoxicillin-Potassium Clavulanate Combination (1) · Bronchoscopy (1)
Wyeth is now a wholly owned subsidiary of Pfizer (4) · Basilea Pharmaceutica (3) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (3) · Pfizer (3) · Rabin Medical Center (2) · Shionogi (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · All India Institute of Medical Sciences (1) · Aridis Pharmaceuticals, Inc. (1) · Assistance Publique - Hôpitaux de Paris (1) · Bayer (1) · Beni-Suef University (1) · C. R. Bard (1) · Creighton University (1) · Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (1)
France (10) · United States (10) · Israel (6) · Italy (6) · Japan (5) · Spain (5) · Brazil (4) · China (4) · India (4) · Russia (4) · Taiwan (4) · Thailand (4) · Turkey (Türkiye) (4) · Ukraine (4) · United Kingdom (4)
Aaron Milstone, MD MHS (1) · Alexandre B Cavalcanti, M.D (1) · Alfredo Guarino, MD (1) · Anil Sachdev, MD (1) · Anthony Gordon, MD FRCA (1) · Avery B Nathens, MD PhD MPH (1) · Bertrand Souweine, Pr (1) · Brian Cuthbertson, MD FRCA (1) · Bruno M Tomazini, M.D (1)
PMID 18508226, PMID 19036670, PMID 19670912, PMID 20211892, PMID 20459721, PMID 24723282, PMID 30808293, PMID 33960817, PMID 34155899, PMID 34792787, PMID 35076335, PMID 41251370, PMID 12749509, PMID 16236177, PMID 16980879, PMID 17076839, PMID 17119142, PMID 18461895, PMID 18549664, PMID 18714060, PMID 18990531, PMID 19036672, PMID 19467544, PMID 19740418, PMID 20302428, PMID 20407057, PMID 20522788, PMID 20522796, PMID 20663130, PMID 21129208, PMID 21558772, PMID 22306046, PMID 22488002, PMID 22760426, PMID 22812672, PMID 23352693, PMID 23363666, PMID 23616495, PMID 24207137, PMID 24708675, PMID 25668557, PMID 25977146, PMID 26096377, PMID 27718118, PMID 29254862, PMID 29454592, PMID 29484469, PMID 29912399, PMID 30061279, PMID 30221827
2015 (1), 2016 (1), 2017 (1), P50HL073996 (1)