64 terminated. 64 Phase 2, 9 Phase 3, 5 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 64 | Terminated 64 |
| Phase 3 | 9 | Terminated 9 |
| Phase 1 | 5 | Terminated 5 |
Follow Covid19: new trials by email Literature Review of Covid19 trials Research Report on Covid19
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| COVID-FIS: Pilot in COVID-19 (SARS-CoV-2) of Fisetin in Older Adults in Nursing Homes Fisetin, Placebo - Covid19, SARS-CoV Infection | Phase 2 | Terminated | Mayo Clinic | 20 | 2022-04-29 | 2025-08-26 |
| Leidos-Enabled Adaptive Protocol (LEAP-CT) for Evaluation of Post-exposure Prophylaxis for Newly-infected COVID-19 Patients Famotidine, Celecoxib, Placebo - 2019 Novel Coronavirus Disease, 2019 Novel Coronavirus Infection | Phase 2 | Terminated | Leidos Life Sciences | 4 | 2021-12-29 | 2024-07-09 |
| Study of Intravenous COVI-MSC for Treatment of COVID-19-Induced Acute Respiratory Distress COVI-MSC, Placebo - Covid19 | Phase 2 | Terminated | Sorrento Therapeutics, Inc. | 43 | 2021-11-16 | 2023-01-09 |
| Clinical Trial to Assess the Efficacy and Safety of Inhaled AQ001S in the Management of Acute COVID-19 Symptoms Drug, inhalation - Covid19 | Phase 2 | Terminated | Aquilon Pharmaceuticals S.A. | 21 | 2021-11-04 | 2023-01-06 |
| AT1001 for the Treatment of COVID-19 Related MIS-C Larazotide Acetate, Placebo - Covid19, Multisystem Inflammatory Syndrome in Children | Phase 2 | Terminated | Massachusetts General Hospital | 12 | 2021-10-01 | 2024-06-13 |
| SARS-Cov-2 (COVID-19) Nasal Pharyngeal and Oral Pharyngeal Wash (SNOW) Trial Shampoo and saline, Saline and Listerine, Shampoo and Listerine - Covid19, SARS-CoV Infection | Phase 2 / Phase 3 | Terminated | Milton S. Hershey Medical Center | 171 | 2021-10-01 | 2026-09-14 |
| Treatment of Pediatric Patients That Lost Sense of Smell Due to COVID-19 Smell Retraining, Budesonide - Dysosmia, Anosmia | Phase 1 / Phase 2 | Terminated | Amanda Stapleton | 20 | 2021-09-30 | 2024-06-13 |
| Safety and Efficacy of Intranasal Administration of Niclosamide (UNI91103) in Adults With Asymptomatic or Mild COVID-19 Niclosamide, Placebo - Covid19 | Phase 2 | Terminated | UNION therapeutics | 4 | 2021-09-03 | 2022-02-21 |
| INvestigating TELmisartin Study Telmisartan Oral Product, Placebo - Covid19 | Phase 2 | Terminated | University of Hawaii | 24 | 2021-09-01 | 2022-07-01 |
| Study to Evaluate the Effects of Tempol (MBM-02) in COVID-19 Patients. Tempol, Placebo - Covid19 | Phase 2 / Phase 3 | Terminated | Adamis Pharmaceuticals Corporation | 248 | 2021-09-01 | 2022-12-06 |
| A Phase 2b Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study, Evaluating Efficacy and Safety of Allocetra-OTS in Patients With Severe or Critical COVID-19 With Associated Acute Respiratory Distress Syndrome (ARDS) ALLOCETRA-OTS, Placebo - Covid19 | Phase 2 | Terminated | Enlivex Therapeutics Ltd. | 12 | 2021-09-01 | 2024-03-13 |
| Dose-Finding, Safety, and Efficacy Study of XVR011 Added to Standard of Care in Patients Hospitalised for COVID-19 XVR011 - Covid19 | Phase 1 / Phase 2 | Terminated | ExeVir Bio BV | 27 | 2021-08-26 | 2022-04-15 |
| Human Intravenous Interferon Beta-Ia Safety and Preliminary Efficacy in Hospitalized Subjects With COVID-19 IFN beta-1a, Dexamethasone - Covid19 | Phase 2 | Terminated | Faron Pharmaceuticals Ltd | 7 | 2021-08-23 | 2023-07-21 |
| DISulfiram for COvid-19 (DISCO) Trial Disulfiram, Placebo - Covid19 | Phase 2 | Terminated | University of California, San Francisco | 11 | 2021-08-18 | 2023-09-13 |
| Estradiol and Progesterone in Hospitalized COVID-19 Patients Placebo injection and placebo pill, Estradiol Cypionate 5 mg/ml, Progesterone 200 mg Oral Capsule - Covid19 | Phase 2 | Terminated | Tulane University | 10 | 2021-07-22 | 2023-06-27 |
| Study to Evaluate a Single Intranasal Dose of STI-2099 (COVI-DROPS™) in Outpatient Adults With COVID-19 (UK) COVI-DROPS, Placebo - Covid19 | Phase 2 | Terminated | Sorrento Therapeutics, Inc. | 179 | 2021-07-16 | 2023-01-30 |
| Antithrombin III in Infectious Disease Caused by COVID-19 Antithrombin III - Antithrombin III Deficiency, Covid19 | Phase 2 | Terminated | Enrique Ginzburg | 52 | 2021-07-06 | 2022-09-07 |
| A Study of Inhaled Ampion in Adults With Respiratory Distress Due to COVID-19 Ampion, Placebo - Covid19 | Phase 2 | Terminated | Ampio Pharmaceuticals. Inc. | 200 | 2021-06-22 | 2022-12-07 |
| Treatment of Respiratory Complications Associated With COVID-19 Using Umbilical Cord Mesenchymal Stromal Cells Allogeneic Wharton's jelly-MSCs (WJ-MSC), Placebo - Covid19 | Phase 2 | Terminated | McGill University Health Centre/Research Institute of the McGill University Health Centre | 19 | 2021-06-14 | 2025-09-08 |
| Nebulized Heparin for COVID19-associated Acute Respiratory Failure Heparin, Placebo - Covid19 | Phase 2 | Terminated | Brittany Bissell | 2 | 2021-05-20 | 2022-10-18 |
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COVID-19 (64) · Coronavirus Infections (6) · Severe Acute Respiratory Syndrome (6) · Respiratory Distress Syndrome (4) · Respiratory Insufficiency (3) · Hypoxia (2) · Anosmia (1) · Antithrombin III Deficiency (1) · Cytokine Release Syndrome (1) · Diabetes Mellitus (1) · Emergencies (1) · Hereditary Sensory and Autonomic Neuropathies (1) · Hypertension (1) · Lung Diseases, Interstitial (1) · Lymphopenia (1)
Coronaviridae Infections (64) · Infections (64) · Lung Diseases (64) · Nidovirales Infections (64) · Pneumonia (64) · RNA Virus Infections (64) · Respiratory Tract Diseases (64) · Pneumonia, Viral (63) · Respiratory Tract Infections (63) · Virus Diseases (63) · Coronavirus Infections (58) · Pathological Conditions, Signs and Symptoms (7) · Respiration Disorders (6) · Signs and Symptoms (4) · Pathologic Processes (3)
camostat (4) · Niclosamide (3) · Standard of Care (3) · Colchicine (2) · Hydroxychloroquine (2) · Ivermectin (2) · 11-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,26-triazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene (1) · Antithrombin III (1) · Atovaquone (1) · Azithromycin (1) · Budesonide (1) · Celecoxib (1) · Cell- and Tissue-Based Therapy (1) · Cetylpyridinium (1) · Chlorhexidine (1)
Massachusetts General Hospital (2) · Sorrento Therapeutics, Inc. (2) · University of North Carolina, Chapel Hill (2) · Adamis Pharmaceuticals Corporation (1) · Amanda Stapleton (1) · Ampio Pharmaceuticals. Inc. (1) · Aquilon Pharmaceuticals S.A. (1) · Arcturus Therapeutics, Inc. (1) · Asociación Argentina de Medicina Hiperbárica e Investigación (1) · Baptist Health South Florida (1) · BioAge Labs, Inc. (1) · Brittany Bissell (1) · CES University (1) · CTI BioPharma (1) · Charite University, Berlin, Germany (1)
United States (38) · Brazil (5) · Argentina (4) · Belgium (3) · Germany (3) · Italy (3) · Mexico (3) · Spain (3) · Canada (2) · Colombia (2) · Moldova (2) · Philippines (2) · South Africa (2) · Switzerland (2) · Ukraine (2)
Mike Royal, MD (2) · Adit Ginde, MD MPH, (1) · Amanda L Stapleton, MD (1) · Brandon P Verdoorn, MD (1) · Brian A Roberts, MS, PMP (1) · Brittany D Bissell (1) · Cecilia M Shikuma (1) · Chaitan Khosla, PhD (1) · Christine M Bojanowski, MD (1) · Daniel Talmor, MD MPH, (1) · Darcy V Spicer, MD (1) · Deonne Thaddeus V Gauiran, MD (1) · Douglas Maslin, MD (1) · Dr Deven Parmar, MD (1) · Eleftherios Mylonakis, MD PhD FIDSA (1)
PMID 34473343, PMID 15030519, PMID 15885816, PMID 17276373, PMID 18434652, PMID 18752857, PMID 19190233, PMID 21423999, PMID 22496216, PMID 23412700, PMID 25666761, PMID 25816117, PMID 26166259, PMID 28325826, PMID 28880869, PMID 29414327, PMID 30668322, PMID 31986264, PMID 32031570, PMID 32075786, PMID 32108857, PMID 32109013, PMID 32112977, PMID 32142651, PMID 32167524, PMID 32215618, PMID 32298251, PMID 32338708, PMID 32584326, PMID 32736597, PMID 33050459, PMID 34658014, PMID 34848523, PMID 35172891, PMID 35285015, PMID 35803469, PMID 35976136, PMID 36056913, PMID 36127739, PMID 36173596, PMID 36469321, PMID 36549549, PMID 36622724, PMID 37184292, PMID 37291677, PMID 37782370, PMID 37970658, PMID 39349554, PMID 39911044, PMID 40692836
R01AG072301 (1)