46 completed, 15 terminated, 11 recruiting, 8 unknown. 36 Phase 2, 20 Phase 1, 10 Not applicable, 4 Phase 3, 2 Phase 4.
Follow Lymphopenia: new trials by email Literature Review of Lymphopenia trials Research Report on Lymphopenia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| NAI for Sepsis With Persistent Lymphopenia Nogapendekin alfa inbakicept (NAI), Standard of Care (SOC) - Sepsis, Septic Shock | Phase 2 | Not yet recruiting | ImmunityBio, Inc. | 50 | 2026-07-06 | 2026-05-11 |
| Study of Nogapendekin Alfa Inbakicept and iNKT Cells in Critically Ill Adults With Severe Community-Acquired Pneumonia Nogapendekin alfa inbakicept (NAI), agenT-797 - Community-Acquired Pneumonia (CAP), Acute Respiratory Distress Syndrome (ARDS) | Phase 3 | Withdrawn | ImmunityBio, Inc. | 2026-04-15 | 2026-05-08 | |
| Nogapendekin Alfa-Inbakicept and iNKT Cells for Critically Ill Adults With Severe Community-Acquired Pneumonia (With or Without Sepsis/ARDS) Nogapendekin Alfa-Inbakicept (NAI), Allogeneic invariant Natural Killer T (iNKT) Cells (AgenT-797) - Acute Respiratory Distress Syndrome, Severe Community-Acquired Pneum | Phase 2 | Withdrawn | ImmunityBio, Inc. | 2026-04-15 | 2026-05-08 | |
| Analysis of the Therapeutic and Clinical Profile of Cannabinoid Treatments: A Real-World Study Participants are followed while using cannabis-based products (such as CBD or THC oils, extracts, or isolates) as prescribed by their own physicians for therapeutic purposes. - Chronic Pain, Depression Disorders | Enrolling by invitation | Santa Catarina Federal University | 384 | 2026-03-01 | 2026-03-30 | |
| Evaluation of the Effect of Cordycepin on CD8+ Lymphocytopenia in Patients With Solid Tumors PRaG-1, Placebo - Solid Cancer, Lymphopenia | Phase 2 | Recruiting | Second Affiliated Hospital of Soochow University | 127 | 2025-12-01 | 2026-01-09 |
| PRaG-1 Plus PRaG Therapy in in Elderly Patients With Advanced Solid Tumors: A Prospective Clinical Trial (PRaG 10.0) PD -1/PD-L1 monoclonal antibody - Solid Cancer, Lymphopenia | Phase 2 | Recruiting | Second Affiliated Hospital of Soochow University | 65 | 2025-12-01 | 2026-10-27 |
| Immunological Effects of Iron Supplementation in HHT Disease Blood test at D0, Blood test at D+3 months - Hereditary Haemorrhagic Telangiectasia | Not applicable | Recruiting | Hospices Civils de Lyon | 155 | 2025-09-24 | 2025-10-03 |
| Predictive Performance of a Generative Model for Corneal Tomography After ICL Implantation Corneal tomography generation model after ICL surgery - ICL, Vault | Recruiting | Second Affiliated Hospital of Nanchang University | 818 | 2025-07-01 | 2025-08-28 | |
| A Single-arm, Dose-escalation Trial of Long-acting Recombinant Human IL-7 (NT-I7, Efineptakin Alfa) for Idiopathic CD4 Lymphopenia Recombinant human interleukin (IL) 7-hyFc - Idiopathic CD4 Lymphopenia | Phase 1 / Phase 2 | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 60 | 2024-11-06 | 2026-10-19 |
| Thymalfasin and Recombinant Human IL-2 Injections in Treating Lymphocytopenia for Patients With Malignant Hematological Tumors Thymalfasin for injection in combination with Recombinant Human Interleukin-2 Injections, Recombinant Human Interleukin-2 Injections - Hematological Malignancy, Lymphocytopenia | Phase 2 | Recruiting | The First Affiliated Hospital of Xiamen University | 50 | 2024-09-01 | 2024-09-19 |
| Serologic Response to Pneumococcal Vaccination Among Esophageal Cancer Patients With High Grade Lymphopenia After Chemoradiation Pneumonia vaccine - Pneumococcal Vaccine, Esophageal Cancer | Recruiting | M.D. Anderson Cancer Center | 80 | 2024-02-05 | 2026-05-20 | |
| To Compare the Clinical Outcomes of FemtoLASIK and ICL Implantation in Treating Moderate Myopia Focusing on Refractive Stability, Contrast Sensitivity and High Order Aberrations. FemtoLASIK, ICL implantation - Myopia, Moderate | Not applicable | Completed | Walid Osama Abdel Rahman Nour El Din | 60 | 2023-01-01 | 2025-12-18 |
| Baby Detect : Genomic Newborn Screening Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1 | Completed | Centre Hospitalier Universitaire de Liege | 6824 | 2022-09-01 | 2025-08-12 | |
| Persistent Lymphopenia in Liver Transplantation and Its Molecular Insights for Hepatocellular Carcinoma Lymphopenia | Completed | Chang Gung Memorial Hospital | 190 | 2022-03-01 | 2024-04-18 | |
| CD8+ T-cell PET/CT Imaging in COVID-19 Patients [89Zr]Df-IAB22M2C PET/CT scan - Lymphopenia Due to COVID-19, T-cell | Terminated | Radboud University Medical Center | 5 | 2022-02-14 | 2025-04-02 | |
| Short Course Chemo-Radiation Therapy for Patients With Newly Diagnosed Glioblastoma Radiation Therapy, Temozolomide Oral Product - Glioblastoma | Phase 1 / Phase 2 | Active not recruiting | John Flickinger | 2 | 2021-12-14 | 2025-06-18 |
| Evaluation of Adenosine Deaminase (ADA) Enzyme Deficiency in Patients With Lymphopenia and/or Elevated Immunoglobulin E ADENOSINE DEAMINASE TEST - Adenosine Deaminase Deficiency | Unknown | TRPHARM | 100 | 2021-12-03 | 2022-03-29 | |
| Study of Lymphopenia as a Specific Biomarker or Prognostic Risk Factor for Disease Severity in Elderly Patients With COVID-19 observation no intervention - Lymphopenia, Covid19 | Completed | Universitair Ziekenhuis Brussel | 227 | 2021-06-30 | 2023-01-31 | |
| InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic pAtients With COVID-19 Infection (Brazil Cohort) Interleukin-7, PLACEBO - COVID-19, Lymphocytopenia | Phase 2 | Terminated | Revimmune | 4 | 2021-03-01 | 2024-04-12 |
| InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic Patients With COVID-19 Infection ( ILIAD-7-US-O ) CYT107, Placebo - COVID-19, Lymphocytopenia | Phase 2 | Terminated | Revimmune | 10 | 2020-12-20 | 2024-04-11 |
Showing 20 of 93. Sign in to see all of them.
Wiskott-Aldrich Syndrome (41) · Granulomatous Disease, Chronic (13) · Primary Immunodeficiency Diseases (13) · COVID-19 (12) · Anemia, Diamond-Blackfan (10) · Chediak-Higashi Syndrome (10) · Severe Combined Immunodeficiency (10) · T-Lymphocytopenia, Idiopathic CD4-Positive (10) · Anemia, Sickle Cell (9) · Immunologic Deficiency Syndromes (9) · Lymphohistiocytosis, Hemophagocytic (9) · Common Variable Immunodeficiency (8) · Hyper-IgM Immunodeficiency Syndrome (8) · Lymphoproliferative Disorders (6)
Hemic and Lymphatic Diseases (93) · Leukocyte Disorders (93) · Leukopenia (93) · Cytopenia (92) · Hematologic Diseases (92) · Immune System Diseases (90) · Immunologic Deficiency Syndromes (84) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (43) · Hemorrhagic Disorders (43) · Blood Coagulation Disorders, Inherited (41) · Genetic Diseases, X-Linked (41) · Blood Coagulation Disorders (40) · Genetic Diseases, Inborn (38) · Primary Immunodeficiency Diseases (28)
Interleukin-7 (8) · Cyclophosphamide (5) · Melphalan (5) · Sodium Chloride (5) · fludarabine phosphate (5) · Peripheral Blood Stem Cell Transplantation (4) · fludarabine (4) · gamma-Globulins (4) · ALT-803 (3) · Busulfan (3) · Methotrexate (3) · Thiotepa (3) · Whole-Body Irradiation (3) · efineptakin alfa (3) · Alemtuzumab (2)
National Institute of Allergy and Infectious Diseases (NIAID) (7) · Revimmune (6) · ImmunityBio, Inc. (4) · Federal Research Institute of Pediatric Hematology, Oncology and Immunology (3) · Genethon (3) · National Human Genome Research Institute (NHGRI) (3) · Paul Szabolcs (3) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (3) · Bio Products Laboratory (2) · Centre Hospitalier Universitaire de Saint Etienne (2) · Centre Leon Berard (2) · Children's Hospital Los Angeles (2) · Emory University (2) · Fondazione Telethon (2) · Hospices Civils de Lyon (2)
United States (49) · France (13) · China (5) · Italy (4) · Canada (3) · Russia (3) · United Kingdom (3) · Belgium (2) · Brazil (2) · Egypt (2) · Turkey (Türkiye) (2) · Chile (1) · Germany (1) · Israel (1) · Mexico (1)
Irini Sereti, M.D. (3) · Paul Szabolcs, MD (3) · Elizabeth K Garabedian, R.N. (2) · Marcel van den Brink, MD, PhD (2) · Alexandra H. Filipovich, MD (1) · Alexei Maschan, Professor (1) · Andrea Lisco, M.D. (1) · Anna Shcherbina, MD, PhD (1) · Benjamin Schleenvoigt, M.D. (1) · Biljana Horn, MD (1) · David J. Rawlings, MD (1) · Dmitry Balashov (1) · Dolores Grosso, DNP, CRNP (1) · Eleftherios Mylonakis, MD PhD FIDSA (1)
PMID 39903535, PMID 32031570, PMID 32171076, PMID 29515037, PMID 35075289, PMID 19549917, PMID 23053510, PMID 36818468, PMID 38446574, PMID 42777242, PMID 10561360, PMID 10737767, PMID 12010786, PMID 12411295, PMID 12610500, PMID 12628464, PMID 12759326, PMID 12816983, PMID 14557216, PMID 14615453, PMID 15503313, PMID 15569976, PMID 15629410, PMID 15841203, PMID 15905493, PMID 16163382, PMID 16249702, PMID 16557261, PMID 16699374, PMID 17135638, PMID 17273548, PMID 17320482, PMID 18456875, PMID 18568246, PMID 18573906, PMID 18946659, PMID 19244125, PMID 19287090, PMID 19380868, PMID 19396174, PMID 19645607, PMID 19808962, PMID 19933849, PMID 20004776, PMID 20537187, PMID 20651586, PMID 21403129, PMID 21725047, PMID 21789273, PMID 21921156
2009 (2), 2018 (1), P30CA015704 (1), UM1CA137443 (1)