12 completed, 9 unknown, 4 recruiting, 2 not yet recruiting. 17 Not applicable, 5 Phase 3, 1 Early Phase 1, 1 Phase 1, 1 Phase 2.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Natural History of MTBI-related Convergence Insufficiency & Effectiveness of Vision Therapy for MTBI-related CI Office-Based Vergence/Accommodative Therapy with Movement (OBVAM) - Convergence Insufficiency | Phase 2 | Not yet recruiting | Salus University | 100 | 2026-11-01 | 2025-02-27 |
| Effectiveness of Osteopathy as an Adjunct to Optometric Vision Therapy in Vergence Disorders Optometric Vision Therapy, Osteopathic Manual Therapy, Sham Osteopathic Intervention - Vergence Disorders, Binocular Vision Dysfunction | Not applicable | Recruiting | Jordi Zaragoza | 100 | 2026-09-07 | 2026-10-13 |
| Home-based Vision Therapy Virtual-reality convergence training game - Convergence Insufficiency | Phase 1 | Recruiting | VA Office of Research and Development | 45 | 2026-01-14 | 2026-01-20 |
| Effect of Oculomotor Therapy in Individuals With Convergence Insufficiency Oculomotor therapy, No Treatment Added - Convergence Insufficiency | Not applicable | Not yet recruiting | University of Nove de Julho | 70 | 2025-08-01 | 2025-06-25 |
| Efficacy Of Pencil Pushup Exercise Vs Base Out Exercising Prism's In Patient With Convergence Insufficiency base-out exercising prisms, pencil pushup exercises - Convergence Insufficiency | Not applicable | Active not recruiting | Superior University | 28 | 2025-03-20 | 2025-04-06 |
| Non-invasive Brain Stimulation for Treating Symptomatic Convergence Insufficiency Anodal-Transcranial Direct Current Stimulation, Office-Based Vergence/Accommodative Therapy, Sham Transcranial Direct Current Stimulation - Convergence Insufficiency | Not applicable | Recruiting | Midwestern University | 150 | 2025-03-01 | 2024-12-02 |
| Eye Recovery Automation for Post Injury Dysfunction (iRAPID) Virtual Eye Rotation Vision Exercise (VERVE), Sham VR Therapy - Convergence Insufficiency, Traumatic Brain Injury | Not applicable | Recruiting | New Jersey Institute of Technology | 100 | 2023-10-23 | 2026-04-14 |
| The Effectiveness of Visual Training in Convergence Insufficiency Patients Visual training - Convergence Insufficiency | Not applicable | Completed | National Taiwan University Hospital | 12 | 2023-03-06 | 2024-12-03 |
| Effect of Exercises on Convergence Insufficiency in Individuals With Temporomandibular Disorders Oculomotor Therapy, Therapy for Temporomandibular Disorder - Temporomandibular Disorder, Temporomandibular Joint Disorders | Not applicable | Unknown | University of Nove de Julho | 24 | 2023-02-01 | 2024-03-06 |
| The Health-Related Quality of Life of the Patients With Symptomatic Convergence Insufficiency Visual training in hospital - Myopia, Convergence Insufficiency | Unknown | Tianjin Eye Hospital | 300 | 2022-06-01 | 2023-07-17 | |
| Home Vision Therapy and Prism Prescription in Presbyopic Persons With Convergence Insufficiency home vision therapy, base in prism prescription, conventional placebo - Convergence Insufficiency | Not applicable | Unknown | Shahid Beheshti University of Medical Sciences | 250 | 2022-04-03 | 2023-04-25 |
| Neurolens Convergence Insufficiency Study Neurolens spectacle lens, Placebo spectacle lens - Binocular Vision Disorder, Convergence Insufficiency | Not applicable | Terminated | Neurolens Inc. | 50 | 2021-11-22 | 2023-10-13 |
| Neurolens Headache Study Neurolens spectacle lens, Placebo spectacle lens - Binocular Vision Disorder, Convergence Insufficiency | Not applicable | Completed | Neurolens Inc. | 300 | 2021-10-18 | 2023-10-12 |
| Effectiveness of Virtual Reality Vision Therapy - VERVE Virtual Eye Rotation Vision Exercises (VERVE) - Convergence Insufficiency | Early Phase 1 | Unknown | OculoMotor Technologies | 50 | 2021-10-14 | 2024-04-16 |
| Persistent Post-Concussion Symptoms With Convergence Insufficiency Office-based Vergence and Accommodative Therapy - Persistent Post-concussive Symptoms, Convergence Insufficiency | Not applicable | Completed | New Jersey Institute of Technology | 112 | 2021-09-01 | 2026-01-22 |
| Effect of Vergence Exercises for Patients With Convergence Insufficiency After Concussion. Vergence exercises (Orthoptic exercises), Placebo - Concussion, Mild, Convergence Insufficiency | Not applicable | Unknown | Danish College of Optometry and Vision Science | 100 | 2021-07-01 | 2023-09-11 |
| Interventions for Convergence Insufficiency in Concussed Children Standard Community Concussion Care (SC), SC plus Simple Convergence Exercises (SC+), SC plus Office-based Vergence/Accommodative Therapy (SC+OBVAT) - Concussion, Convergence Insufficiency | Phase 3 | Unknown | Mitchell Scheiman | 264 | 2021-04-01 | 2020-10-23 |
| Objective Assessment of Disparity Vergence After Treatment of Symptomatic CI in Children office-based vergence/accommodative therapy - Convergence Insufficiency | Not applicable | Unknown | Salus University | 60 | 2018-09-02 | 2020-10-23 |
| Spectacles Lens in Concussed Kids Glasses - Concussion, Mild, Convergence Insufficiency | Not applicable | Terminated | University of Alabama at Birmingham | 10 | 2017-10-31 | 2022-06-23 |
| Eyetracking and Neurovision Rehabilitation of Oculomotor Dysfunction in Mild Traumatic Brain Injury Mild Traumatic Brain Injury, Brain Concussion | Completed | Hennepin Healthcare Research Institute | 92 | 2017-10-18 | 2020-10-19 |
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Ocular Motility Disorders (30) · Brain Concussion (7) · Headache (2) · Attention Deficit Disorder with Hyperactivity (1) · Brain Injuries, Traumatic (1) · Dyslexia (1) · Myopia (1) · Refractive Errors (1) · Strabismus (1) · Temporomandibular Joint Disorders (1) · Temporomandibular Joint Dysfunction Syndrome (1) · Vision Disorders (1)
Central Nervous System Diseases (30) · Cranial Nerve Diseases (30) · Eye Diseases (30) · Nervous System Diseases (30) · Brain Diseases (7) · Brain Injuries (7) · Craniocerebral Trauma (7) · Head Injuries, Closed (7) · Trauma, Nervous System (7) · Wounds and Injuries (7) · Wounds, Nonpenetrating (7) · Brain Injuries, Traumatic (6) · Neurologic Manifestations (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3)
Orthoptics (2) · Alkalies (1) · Botulinum Toxins (1) · Botulinum Toxins, Type A (1) · Eyeglasses (1) · Hospitals (1) · Movement (1) · Saline Solution, Hypertonic (1) · Therapeutics (1) · Transcranial Direct Current Stimulation (1)
New Jersey Institute of Technology (3) · Salus University (3) · Jaeb Center for Health Research (2) · Neurolens Inc. (2) · Ohio State University (2) · Pennsylvania College of Optometry (2) · University of Nove de Julho (2) · Danish College of Optometry and Vision Science (1) · Hennepin Healthcare Research Institute (1) · Johns Hopkins University (1) · Jordi Zaragoza (1) · Midwestern University (1) · Mitchell Scheiman (1) · National Eye Institute (NEI) (1) · National Taiwan University Hospital (1)
United States (19) · Andorra (1) · Brazil (1) · China (1) · Denmark (1) · Iran (1) · Pakistan (1) · Taiwan (1)
Mitchell Scheiman, OD (4) · Chang Yaramothu, PhD (2) · Marjean Kulp, OD, MS (2) · Mitchell Scheiman, OD, PhD (2) · Tara L Alvarez, PhD (2) · Atam Dhawan, PhD (1) · Becky Luu, OD (1) · Corina Van De Pol, OD PhD (1) · Corina Van de Pol, OD, PhD (1) · Darren L Hoover, MD (1) · David S Friedman, MD, MPH, PhD (1) · Earl R Crouch, III, MD (1) · Katherine Weise, OD (1) · Levelle Jenkins, OD (1)
PMID 33263359, PMID 15642806, PMID 16044063, PMID 16170124, PMID 18852411, PMID 19151384, PMID 19668097, PMID 19741558, PMID 20543758, PMID 22922781, PMID 27575992, PMID 31112777, PMID 31640452, PMID 31651592, PMID 31651593, PMID 33753864, PMID 33771952, PMID 34271207, PMID 35914096, PMID 37982763, PMID 38622543, PMID 39185637, PMID 39546477, PMID 41033748, PMID 41252526
R01EY023261 (2), U10EY011751 (2), R21EY013164 (1), U10EY022599 (1)