64 completed, 9 withdrawn, 5 unknown, 1 active not recruiting. 81 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 81 | Completed 64, Withdrawn 9, Unknown 5, Active not recruiting 1, Not yet recruiting 1, Terminated 1 |
Follow Conjunctivitis: new trials by email Literature Review of Conjunctivitis trials Research Report on Conjunctivitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of the Impact of Oral Ivermectin on Musca Sorbens Flies, Putative Vector of Trachoma Ivermectin - Survival of Flies Developing in Faecal Samples | Phase 4 | Not yet recruiting | London School of Hygiene and Tropical Medicine | 12 | 2026-10-05 | 2026-10-30 |
| Trachoma Elimination Study by Focused Antibiotic (TESFA) Azithromycin mass treatment, Azithromycin targeted treatment - Trachoma | Phase 4 | Withdrawn | Emory University | 2025-06-01 | 2025-07-16 | |
| Azithromycin Reduction to Reach Elimination of Trachoma B Azithromycin - Trachoma | Phase 4 | Withdrawn | University of California, San Francisco | 2024-10-01 | 2026-03-13 | |
| Phase 4 Study Evaluating the Safety of the Nasal Guide With Tyrvaya Nasal Guide - Dry Eye, Keratoconjunctivitis Sicca | Phase 4 | Completed | Oyster Point Pharma, Inc. | 30 | 2023-06-14 | 2025-05-06 |
| Clinical and Biological Evaluation of NAAGA Versus Azelastine Eye Drops in Allergic Subjects With Tear Film Dysfunction NAAGA (N-acetyl-aspartyl-glutamate) 49 mg/mL, azelastine hydrochloride 0.05% - Allergic Conjunctivitis, Dry Eye Disease (DED) | Phase 4 | Completed | Azienda Ospedaliera OO.RR. S. Giovanni di Dio e Ruggi D'Aragona | 134 | 2023-04-21 | 2025-07-15 |
| Enhancing the A in SAFE for Trachoma Azithromycin for Routine Community-wide MDA, Two Additional Rounds of Azithromycin for Children, Azithromycin for Second Community-wide MDA - Trachoma | Phase 4 | Completed | Emory University | 34630 | 2022-05-04 | 2024-02-29 |
| Kebele Elimination of Trachoma for Ocular Health Azithromycin - Trachoma | Phase 4 | Active not recruiting | University of California, San Francisco | 320000 | 2022-02-07 | 2025-10-23 |
| A Study Comparing the Efficacy of Pataday® Once Daily Relief Extra Strength to Flonase® Allergy Relief in Subjects With Allergic Conjunctivitis olopatadine hydrochloride ophthalmic solution 0.7%), Fluticasone Propionate, Tears Naturale - Allergic Conjunctivitis | Phase 4 | Completed | Andover Research Eye Institute | 61 | 2021-12-31 | 2022-09-02 |
| A Study Comparing the Efficacy of Pataday® Once Daily Relief Extra Strength to Claritin® Tablets 24-Hour in Subjects With Allergic Conjunctivitis olopatadine hydrochloride ophthalmic solution 0.7%, loratadine 10 mg, Tears Naturale - Allergic Conjunctivitis | Phase 4 | Completed | Andover Research Eye Institute | 58 | 2021-12-14 | 2022-05-03 |
| Cluster RCT of Co-administration Azithromycin, Albendazole & Ivermectin Administration of Albendazole on Day 1, Administration of Ivermectin on Day 1, Administration of Azithromycin on Day 1 - Trachoma, Lymphatic Filariases | Phase 4 | Completed | London School of Hygiene and Tropical Medicine | 13511 | 2021-12-01 | 2022-08-19 |
| The Effect of Upneeq (Oxymetazoline Hydrochloride 0.1%) on Eyelid Position, Eye Redness, and Eye Appearance Oxymetazoline hydrochloride 0.1% ophthalmic solution, Placebo - Ptosis, Eyelid, Conjunctiva Inflamed | Phase 4 | Completed | University of Miami | 114 | 2021-06-08 | 2023-04-24 |
| Azithromycin Reduction to Reach Elimination of Trachoma Azithromycin - Trachoma | Phase 4 | Completed | University of California, San Francisco | 3931 | 2021-05-29 | 2026-03-25 |
| Tolerability Comparison of Flarex to Lotemax SM Fluorometholone Acetate Ophthalmic Suspension 0.1%, Loteprednol Etabonate Ophthalmic Gel 0.38% - Ocular Inflammation, Keratoconjunctivitis | Phase 4 | Completed | Harrow Inc | 40 | 2021-05-01 | 2026-09-22 |
| Efficacy and Toxicity of Bepotastine 1,5% PF vs Olopatadine 0,2% With BAK on Allergic Conjunctivitis Treatment Bepotastine Besilate 1.5% PF, Olopatadine Hydrochloride 0.2% BAK - Allergic Conjunctivitis | Phase 4 | Completed | Laboratorios Poen | 97 | 2021-03-10 | 2022-12-15 |
| Effect of Cequa™ in Subjects With Dry Eye Disease CequaTM (Cyclosporine 0.09%) ophthalmic solution - Dry Eye Disease | Phase 4 | Completed | Sun Pharmaceutical Industries Limited | 135 | 2020-06-29 | 2024-02-06 |
| Manuka Eye Droops for Treatment of Allergy Manuka honey - Allergic Conjunctivitis | Phase 4 | Withdrawn | Toyos Clinic | 2020-01-01 | 2020-10-09 | |
| Effects of Xiidra on Closed Eye Tear Film Leukocytes in Dry Eye Disease Lifitegrast - Ocular Discomfort, Ocular Inflammation | Phase 4 | Withdrawn | University of Alabama at Birmingham | 2019-01-01 | 2019-05-17 | |
| Repository Corticotropin Injection in Keratoconjunctivitis Sicca repository corticotropin injection - Keratoconjunctivitis Sicca | Phase 4 | Withdrawn | University of Alabama at Birmingham | 2018-11-01 | 2018-12-14 | |
| Antibiotic Resistance and Microbiome in Children Aged 6-59 Months in Nouna, Burkina Faso Azithromycin, Amoxicillin, Cotrimoxazole - Child Development | Phase 4 | Completed | University of California, San Francisco | 252 | 2017-07-04 | 2023-03-02 |
| Clinical Evaluation of Hylo-Dual Versus Patanol in Children With Seasonal Allergic Conjunctivitis Hyaluronic acid 0.05% & Ectoine 2.0%, Olopatadine hydrochloride ophthalmic solution 0.1% - Conjunctivitis, Allergic, Conjunctivitis, Vernal | Phase 4 | Unknown | Michael Marchand, MD | 42 | 2017-06-11 | 2022-10-26 |
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Conjunctivitis, Allergic (40) · Trachoma (20) · Dry Eye Syndromes (12) · Keratoconjunctivitis Sicca (11) · Chlamydia Infections (5) · Bacterial Infections (3) · Conjunctivitis, Bacterial (3) · Elephantiasis, Filarial (2) · Eye Diseases (2) · Hypersensitivity (2) · Infections (2) · Keratoconjunctivitis (2) · Adenoviridae Infections (1) · Asthma (1)
Conjunctival Diseases (81) · Eye Diseases (79) · Hypersensitivity, Immediate (40) · Immune System Diseases (40) · Hypersensitivity (38) · Corneal Diseases (33) · Eye Infections (24) · Bacterial Infections and Mycoses (23) · Eye Infections, Bacterial (23) · Infections (23) · Bacterial Infections (20) · Chlamydiaceae Infections (20) · Conjunctivitis, Bacterial (20) · Gram-Negative Bacterial Infections (20)
Olopatadine Hydrochloride (16) · Azithromycin (12) · Lubricant Eye Drops (7) · Ophthalmic Solutions (7) · Loteprednol Etabonate (6) · alcaftadine (5) · bepotastine besilate (5) · Dexamethasone (3) · Dextrans (3) · Fluticasone (3) · Hyaluronic Acid (3) · Moxifloxacin (3) · Carboxymethylcellulose Sodium (2) · Cyclosporine (2) · Ivermectin (2)
Alcon Research (12) · University of California, San Francisco (10) · Allergan (5) · Johns Hopkins University (4) · ORA, Inc. (4) · Emory University (3) · Hom, Milton M., OD, FAAO (3) · London School of Hygiene and Tropical Medicine (3) · Andover Research Eye Institute (2) · Bausch & Lomb Incorporated (2) · Laboratoires Thea (2) · University of Alabama at Birmingham (2) · Azienda Ospedaliera OO.RR. S. Giovanni di Dio e Ruggi D'Aragona (1) · Baylor College of Medicine (1) · EV Clinical Trials (1)
United States (43) · Ethiopia (6) · United Kingdom (4) · Niger (3) · South Korea (3) · Canada (2) · France (2) · Italy (2) · Japan (2) · Tanzania (2) · Argentina (1) · Burkina Faso (1) · China (1) · Democratic Republic of the Congo (1) · Finland (1)
Tom Lietman, MD (3) · Catherine Oldenburg, ScD, MPH (2) · Elodie Lebas, RN (2) · Julius Schachter, PhD (2) · Kieran S O'Brien, MPH (2) · Milton M Hom, OD FAAO (2) · Paul Emerson, PhD (2) · Sheila K West (2) · Tarek Shazly, MD (2) · Thomas M Lietman, MD (2) · Tom M Lietman, MD (2) · Abdou Amza, MD (1) · Adisak Trinavarat, MD (1) · Ahmad M Fahmy, O.D. (1)
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5UG1EY030833 (2), R01AI048789 (2), 1UG1EY028088 (1)