24 completed, 7 terminated, 6 unknown, 2 withdrawn. 41 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 41 | Completed 24, Terminated 7, Unknown 6, Withdrawn 2, Active not recruiting 1, Recruiting 1 |
Follow Congestive Heart Failure: new trials by email Literature Review of Congestive Heart Failure trials Research Report on Congestive Heart Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PVP-Guided Decongestive Therapy in HF 2 Diuretic therapy - Heart Failure, Congestion | Phase 4 | Active not recruiting | Başakşehir Çam & Sakura City Hospital | 650 | 2024-07-01 | 2026-09-30 |
| DECONGEST-AHF: Vasodilatation or Loop Diuretics in Acute Heart Failure Furosemide Injection, Isosorbide Dinitrate, Furosemide and isosorbide dinitrate - Pulmonary Edema, Congestive Heart Failure | Phase 4 | Recruiting | Copenhagen University Hospital, Rigshospitalet | 1041 | 2023-09-14 | 2026-10-23 |
| The Heart Failure Diuresis Efficacy Comparison (DEA-HF) Study IV Furosemide, IV Furosemide and PO Metolazone, IV Furosemide and IV Acetazolamide - Chronic Heart Failure, Diuretics Drug Reactions | Phase 4 | Completed | Rambam Health Care Campus | 42 | 2023-04-19 | 2024-05-21 |
| Sodium-glucose Cotransporter Type 2 Inhibitors for Acute Cardiorenal Syndrome Prevention Standard list of drugs used for acute decompensation of CHF (loop diuretics, vasodilators, digoxin, inotropic agents, vasopressors), plus dapagliflozin (Forxiga; MP-002596) - Congestive Heart Failure | Phase 4 | Completed | I.M. Sechenov First Moscow State Medical University | 370 | 2021-01-01 | 2022-12-07 |
| Ivabradine in Patients With Congestive Heart Failure Ivabradine Oral Tablet, Blacebo plus standard treatment - Congestive Heart Failure | Phase 4 | Completed | Damanhour University | 60 | 2020-06-01 | 2021-08-04 |
| Oral dIuretics in Very Intensive Treatment, an Early Intervention in Outpatients With Heart Failure Bumetanide 1 MG - Heart Failure, Congestive Heart Failure | Phase 4 | Unknown | Centro en Insuficiencia Cardiaca, Mexico | 40 | 2018-10-15 | 2018-10-17 |
| Sacubitril-valsartan Versus Usual Anti-hypertensives in LVAD Entresto, Valsartan - Congestive Heart Failure, Hypertension | Phase 4 | Withdrawn | University of Maryland, Baltimore | 2017-11-01 | 2023-05-06 | |
| Pulmonary Artery Pressure Reduction With ENTresto (Sacubitril/Valsartan) Implantable Hemodynamic Monitor, Angiotensin-Converting Enzyme Inhibitor, Angiotensin II Type 1 Receptor Blocker - Congestive Heart Failure | Phase 4 | Terminated | Brigham and Women's Hospital | 4 | 2016-09-01 | 2020-02-17 |
| Catheter Ablation vs. Medical Therapy in Congested Hearts With AF Catheter Ablation, FDA approved anti arrhythmic drug - Congestive Heart Failure, Left Ventricular Failure | Phase 4 | Terminated | The Cleveland Clinic | 4 | 2016-06-01 | 2025-06-05 |
| Tolvaptan For Worsening Outpatient Heart Failure: Role of Copeptin In Identifying Responders tolvaptan, Placebo - Congestive Heart Failure | Phase 4 | Completed | University of North Carolina, Chapel Hill | 40 | 2015-07-01 | 2022-05-05 |
| Spironolactone Safety in Dialysis Patients spironolactone - End Stage Renal Disease, Congestive Heart Failure | Phase 4 | Withdrawn | State University of New York - Upstate Medical University | 2013-06-30 | 2020-10-22 | |
| Nesiritide and Renal Function After the Total Artificial Heart nesiritide, placebo - Congestive Heart Failure, Cardiorenal Syndrome | Phase 4 | Terminated | Virginia Commonwealth University | 2 | 2013-04-01 | 2016-02-08 |
| THalidomide on Left ventricUlar Morphology aND Function in congEstive heaRt Failure Thalidomide, Placebo - Congestive Heart Failure | Phase 4 | Unknown | University of Roma La Sapienza | 100 | 2012-07-01 | 2013-03-07 |
| To Evaluate the Efficacy and Safety on Blood Pressure In Patients With Hypertension Diagnosed Congestive Heart Failure Candemore tablet, Atacand tablet - Hypertension, Congestive Heart Failure | Phase 4 | Completed | Chong Kun Dang Pharmaceutical | 169 | 2012-01-01 | 2015-09-24 |
| Vitamin D and Mortality in Heart Failure Vitamin D, placebo - Congestive Heart Failure | Phase 4 | Completed | Heart and Diabetes Center North-Rhine Westfalia | 400 | 2010-11-01 | 2016-08-11 |
| Add-on Aliskiren Treatment in Patients With Chronic Congestive Heart Failure Aliskiren, Placebo - Congestive Heart Failure | Phase 4 | Unknown | National Taiwan University Hospital | 60 | 2010-01-01 | 2010-01-20 |
| Stem Cells Therapy in Advanced Heart Failure stem cells infusion - Congestive Heart Failure | Phase 4 | Unknown | University of Campania Luigi Vanvitelli | 30 | 2010-01-01 | 2020-08-13 |
| Effect of Vildagliptin on Left Ventricular Function in Patients With Type 2 Diabetes and Congestive Heart Failure vildagliptin, placebo of vildagliptin - Congestive Heart Failure, Type II Diabetes Mellitus | Phase 4 | Completed | Novartis Pharmaceuticals | 798 | 2009-05-01 | 2020-12-17 |
| Effects of Exenatide in Type 2 Diabetic Patients With Congestive Heart Failure exenatide, Insulin glargine - Type 2 Diabetes Mellitus, Congestive Heart Failure | Phase 4 | Completed | Amsterdam UMC, location VUmc | 27 | 2009-05-01 | 2015-12-09 |
| Cardiac Resynchronization Therapy, Dyspnea and Exercise Tolerance in Patients With Congestive Heart Failure (CHF) Active Cardiac Resynchronization Therapy (CRT) - Congestive Heart Failure | Phase 4 | Terminated | Queen's University | 2 | 2008-10-01 | 2011-07-06 |
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Heart Failure (41) · Hypertension (6) · Dyspnea (3) · Atrial Fibrillation (2) · Cardiovascular Diseases (2) · Diabetes Mellitus, Type 2 (2) · Edema (2) · Insulin Resistance (2) · Myocardial Ischemia (2) · Stroke (2) · Aneurysm (1) · Angina Pectoris (1) · Cardiac Output, Low (1) · Cardio-Renal Syndrome (1) · Diabetes Insipidus (1)
Heart Diseases (40) · Cardiovascular Diseases (39) · Pathological Conditions, Signs and Symptoms (11) · Signs and Symptoms (7) · Vascular Diseases (7) · Pathologic Processes (5) · Respiratory Tract Diseases (4) · Arrhythmias, Cardiac (3) · Endocrine System Diseases (3) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Glucose Metabolism Disorders (3) · Kidney Diseases (3) · Male Urogenital Diseases (3) · Nutritional and Metabolic Diseases (3)
Furosemide (6) · Natriuretic Peptide, Brain (4) · Valsartan (4) · sacubitril and valsartan sodium hydrate drug combination (2) · Acetazolamide (1) · Adrenergic beta-Antagonists (1) · Angiotensin II Type 1 Receptor Blockers (1) · Angiotensin Receptor Antagonists (1) · Angiotensin-Converting Enzyme Inhibitors (1) · Bumetanide (1) · Capsules (1) · Cardiac Resynchronization Therapy (1) · Carvedilol (1) · Catheter Ablation (1) · Defibrillators, Implantable (1)
Biotronik, Inc. (2) · Amsterdam UMC, location VUmc (1) · Başakşehir Çam & Sakura City Hospital (1) · Biotronik SE & Co. KG (1) · Brigham and Women's Hospital (1) · Centro en Insuficiencia Cardiaca, Mexico (1) · Chong Kun Dang Pharmaceutical (1) · Copenhagen University Hospital, Rigshospitalet (1) · Damanhour University (1) · Emory University (1) · Ferrer Internacional S.A. (1) · Guidant Corporation (1) · Heart and Diabetes Center North-Rhine Westfalia (1) · Hyogo Medical University (1) · I.M. Sechenov First Moscow State Medical University (1)
United States (12) · Canada (4) · Japan (4) · Denmark (3) · Germany (3) · Italy (3) · Czechia (2) · Israel (2) · Latvia (2) · Russia (2) · Australia (1) · Austria (1) · Brazil (1) · Egypt (1) · Estonia (1)
Aharon Abbo, MD (1) · Alfonso Castro Beiras, MD, PhD (1) · Anita Deswal, MD MPH MBBS (1) · Anne L. Taylor, M.D. (1) · Antonio Coca, MD, PhD (1) · Antonio P Barretto, Ph.D. (1) · Armin Zittermann, PhD (1) · Chim Lang, MD, FRCP (1) · Chris M. Parker, MD, MSc (1) · Daniel Wu, MD (1) · Denis Roy (1) · Douglas Ander, MD (1) · Eduardo De Teresa, MD, PhD (1) · Emre K Aslanger, Prof (1)
PMID 14987587, PMID 15367828, PMID 17467513, PMID 18565859, PMID 19264750, PMID 19564557, PMID 19673667, PMID 19723695, PMID 20051294, PMID 21742102, PMID 21807324, PMID 21906812, PMID 22451450, PMID 22664754, PMID 22740509, PMID 22798522, PMID 23803951, PMID 24838894, PMID 24970468, PMID 25131977, PMID 26377342, PMID 27418629, PMID 28498942, PMID 28526033, PMID 28835271, PMID 29032139, PMID 30554193, PMID 33586138, PMID 34271173, PMID 38584394, PMID 38696701, PMID 39855451, PMID 42044762
2008 (1)