40 completed, 13 unknown, 8 terminated, 4 not yet recruiting. 47 Not applicable, 7 Phase 2, 3 Phase 3, 2 Phase 4, 1 Phase 1.
Follow Concussion: new trials by email Literature Review of Concussion trials Research Report on Concussion
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Optimized, Neuroplasticity-Enhanced-Depression (ONE-D) Transcranial Magnetic Stimulation (TMS) Treatment for Female Athletes With Co-morbid Depression and Concussion ONE-D TMS protocol and d-cycloserine (125 mg) - Concussion, Depression | Phase 2 / Phase 3 | Not yet recruiting | University of Florida | 35 | 2026-09-01 | 2026-08-18 |
| Rehabilitation, Education, and SElf-management for Adolescents After Mild Traumatic Brain Injury Mindfulness-based intervention, Health Education - Brain Concussion, Mild Traumatic Brain Injury | Not applicable | Not yet recruiting | Molly Cairncross | 72 | 2026-09-01 | 2026-07-13 |
| BCAAs in Concussion 3.0 BCAA, Placebo - Concussion (Diagnosis), MTBI - Mild Traumatic Brain Injury | Phase 2 | Recruiting | Akiva Cohen | 150 | 2026-08-05 | 2026-09-03 |
| Telehealth Specialty Concussion Treatment for Youth Specialist and Pediatrician Co-Management for Early and Effective Concussion Care Delivery to Hasten Your Recovery (SPEEDY Recovery) - Concussion | Not applicable | Not yet recruiting | University of Rhode Island | 10 | 2026-07-18 | 2026-07-30 |
| Effect of Vestibular Rehabilitation on Gait, Balance, and Coordination in Post Concussion Combat Athletes Vestibular Rehabilitation Program, Conventional Post-Concussion Rehabilitation - Concussion Post Syndrome, Concussion | Not applicable | Not yet recruiting | Riphah International University | 44 | 2026-07-01 | 2026-07-21 |
| Cervico-vestibular Home Exercise Program Feasibility Cervico-vestibular Home Exercise Program - Concussion, Sports Injuries in Children | Not applicable | Completed | Texas Scottish Rite Hospital for Children | 30 | 2025-11-26 | 2026-10-05 |
| A Feasibility Study in Combat Athletes With Mild Traumatic Brain Injury Hyberbaric Oxygen Therapy - Mild Traumatic Brain Injury (mTBI), Brain Injury | Not applicable | Enrolling by invitation | Michael Harl | 10 | 2025-08-07 | 2025-08-13 |
| The Effects of Concussion on Gait and Posture in Individuals With Peripheral Vision Loss Concussion, Eye | Withdrawn | Gaylord Hospital, Inc | 2025-05-01 | 2025-07-22 | ||
| BCAAs in Concussion 2.0 BCAA, Placebo - Concussion, Brain, Concussion, Mild | Phase 2 | Completed | Akiva Cohen | 17 | 2025-04-01 | 2026-09-03 |
| rTMS for Military TBI-related Depression Repetitive Transcranial Magnetic Stimulation (rTMS), Sham rTMS - Depressive Symptoms, Mild Traumatic Brain Injury | Not applicable | Recruiting | Henry M. Jackson Foundation for the Advancement of Military Medicine | 198 | 2024-12-16 | 2026-04-29 |
| Oculomotor Rehabilitation After Concussion in Adults: A Feasibility Study Usual Care, Oculomotor exercises delivered in virtual reality - Concussion | Not applicable | Completed | University Health Network, Toronto | 40 | 2024-05-06 | 2026-07-17 |
| Video Review of the Frequency and Assessment of Head Impacts During the FIFA World Cup 2022TM No intervention applied - observational study only - Head Injury, Concussion | Completed | Federation Internationale de Football Association | 832 | 2022-11-20 | 2025-02-11 | |
| EEG Diagnostic for Repetitive Sub-concussive Head Impacts Concussion | Completed | Mayo Clinic | 42 | 2022-09-23 | 2024-06-21 | |
| Effects of Vestibular Rehabilitation in the Treatment of Dizziness and Balance Disturbances After Concussion Vestibular Rehabilitation, Traditional Protocol - Concussion | Not applicable | Completed | Beth Marschner | 10 | 2022-08-25 | 2024-11-21 |
| ImPACT Version 4-Touchscreen: Normative and Reliability Study Normative, Reliability - Concussion | Not applicable | Unknown | ImPACT Applications, Inc. | 1437 | 2022-02-07 | 2023-07-05 |
| Online Treatment Recovery Assistance for Concussion in Kids Online Treatment Recovery Assistance for Concussion in Kids (OnTRACK) - Concussion, MTBI - Mild Traumatic Brain Injury | Not applicable | Unknown | Children's National Research Institute | 408 | 2022-02-01 | 2022-01-11 |
| Detection and Prevention of Concussive Injuries With Smart Technology. Modern microelectrical mechanical systems (MEMS) head-impact sensors, Virtual Reality (VR) Goggle Use with consistent timing of Conditioned Stimulus and Unconditioned Stimulus, Virtual Reality (VR) Goggle Use with inconsistent timing of Conditioned Stimulus and Unconditioned Stimulus - Concussion, Head Injury Trauma | Not applicable | Unknown | Chi-Ming Huang | 100 | 2021-06-01 | 2021-07-01 |
| Interventions for Convergence Insufficiency in Concussed Children Standard Community Concussion Care (SC), SC plus Simple Convergence Exercises (SC+), SC plus Office-based Vergence/Accommodative Therapy (SC+OBVAT) - Concussion, Convergence Insufficiency | Phase 3 | Unknown | Mitchell Scheiman | 264 | 2021-04-01 | 2020-10-23 |
| Sphenopalatine Ganglion Block for Headache After Concussion Lidocaine in SphenoCath device, Saline Solution in SphenoCath device - Concussion, Headache | Phase 2 | Terminated | University of Michigan | 2 | 2021-03-18 | 2022-09-14 |
| Neurofeedback Impact on Veterans With mTBI Neurofeedback (NFB) - Concussion, mTBI | Not applicable | Completed | VA Office of Research and Development | 87 | 2021-03-16 | 2025-10-30 |
Showing 20 of 74. Sign in to see all of them.
Brain Concussion (74) · Brain Injuries, Traumatic (11) · Post-Concussion Syndrome (9) · Brain Injuries (7) · Stress Disorders, Post-Traumatic (4) · Cognitive Dysfunction (3) · Depression (3) · Dizziness (3) · Motor Activity (3) · Athletic Injuries (2) · Headache (2) · Multiple Sclerosis (2) · Parkinson Disease (2) · Alzheimer Disease (1) · Amyotrophic Lateral Sclerosis (1)
Brain Diseases (74) · Central Nervous System Diseases (74) · Head Injuries, Closed (74) · Nervous System Diseases (74) · Trauma, Nervous System (74) · Wounds and Injuries (74) · Wounds, Nonpenetrating (74) · Craniocerebral Trauma (73) · Brain Injuries (67) · Brain Injuries, Traumatic (63) · Mental Disorders (7) · Behavior (6) · Neurologic Manifestations (6) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (5)
Exercise (2) · Acetaminophen (1) · Blood Specimen Collection (1) · Docosahexaenoic Acids (1) · Drug Delivery Systems (1) · Exercise Test (1) · Ibuprofen (1) · Lidocaine (1) · Magnetic Resonance Imaging (1) · Melatonin (1) · Mental Status and Dementia Tests (1) · Methods (1) · Micro-Electrical-Mechanical Systems (1) · Mindfulness (1) · Neurofeedback (1)
Children's Hospital Medical Center, Cincinnati (6) · Akiva Cohen (2) · Duke University (2) · Jan Medical, Inc. (2) · McGill University Health Centre/Research Institute of the McGill University Health Centre (2) · NYU Langone Health (2) · Spaulding Rehabilitation Hospital (2) · Sport Injury Prevention Research Centre (2) · University at Buffalo (2) · University of Calgary (2) · VA Office of Research and Development (2) · Wake Forest University Health Sciences (2) · Beth Marschner (1) · Brain & Body Health Foundation (1) · BrainCheck, Inc. (1)
United States (50) · Canada (10) · France (3) · Denmark (1) · Pakistan (1)
Gregory D Myer, PhD (4) · Daniel Corwin, MD (2) · Shane Miller, MD (2) · Adam Kiefer, PhD (1) · Alex Hishaw, MD (1) · Ann E Glang, PhD (1) · Beth Marschner, DPT (1) · Brad Kurowski, MD, MS (1) · Brian O'Neil, MD (1) · Catherine Chan, Physiotherapy (1) · Chad Scarboro, MD (1) · Chantel T Debert, MD MSc FRCPC CSCN (1) · Christopher M Miles, MD (1) · Danny G Thomas, MD, MPH (1)
PMID 31377190, PMID 16179657, PMID 19387313, PMID 25438964, PMID 25560444, PMID 26231756, PMID 27120294, PMID 27307271, PMID 27479847, PMID 27624513, PMID 28365025, PMID 28437225, PMID 28989074, PMID 30715132, PMID 31518280, PMID 31620073, PMID 32217739, PMID 32493066, PMID 32772826, PMID 33201041, PMID 35315783, PMID 35722886, PMID 35723922, PMID 38468511, PMID 38980666, PMID 39969142, PMID 40584527, PMID 40598011, PMID 42388887
R15DC015338 (1), R44HD056610 (1), UL1TR001412 (1)