260 completed, 72 recruiting, 70 unknown, 46 terminated. 130 Phase 2, 119 Not applicable, 75 Phase 1, 48 Phase 3, 20 Phase 4.
Follow Skin Abnormalities: new trials by email Literature Review of Skin Abnormalities trials Research Report on Skin Abnormalities
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Epidermal Growth Factor Receptor Inhibition for Keratinopathies Erlotinib - Epidermolytic Ichthyosis, Palmoplantar Keratoderma | Phase 1 / Phase 2 | Not yet recruiting | Northwestern University | 44 | 2027-07-01 | 2026-08-03 |
| An Exercise and Lifestyle Programme for Adults With Vascular Ehlers-Danlos Syndrome: A Feasibility Study Co-designed exercise-based lifestyle intervention - Vascular Ehlers Danlos Syndrome | Not applicable | Not yet recruiting | Sheffield Hallam University | 40 | 2027-03-01 | 2026-07-13 |
| Regenerative Medicine for Joint Hypermobility and Instability Dextrose 20% Prolotherapy, Autologous Platelet-Rich Plasma, Doxycycline Hyclate Injectable (Investigational) - Ehlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS) | Phase 1 / Phase 2 | Not yet recruiting | Manhattan Pain Medicine, PLLC | 100 | 2027-01-15 | 2026-10-06 |
| Study on Influencing Factors of Skin Complications Related to Insulin Injection in Children With Type 1 Diabetes Mellitus Diabetes (Insulin-requiring, Type 1 or Type 2), Skin Abnormalities | Not yet recruiting | The Children's Hospital of Zhejiang University School of Medicine | 199 | 2026-12-01 | 2026-05-29 | |
| Safety, Tolerability, and Efficacy of Oral KM-023 in Adult Patients With Pachyonychia Congenita (pEDD-PC) KM-023 - Pachyonychia Congenita | Phase 2 | Not yet recruiting | Orvida Pharma (formerly Kamari Pharma) | 10 | 2026-12-01 | 2026-10-26 |
| An Open Label Extension Safety Study to Evaluate SD-101 in Epidermolysis Bullosa SD-101 Dermal Cream (6%) - Epidermolysis Bullosa (EB) | Phase 3 | Not yet recruiting | Paradigm Therapeutics | 80 | 2026-11-15 | 2026-09-09 |
| Phase 4 Master Protocol for Patients Prescribed Prademagene Zamikeracel for the Treatment of Wounds Non-conforming pz-cel surgical application to RDEB wounds, Additional biopsies, Pz-cel surgical application to DEB wounds - Epidermolysis Bullosa (EB), Recessive Dystrophic Epidermolysis Bullosa (RDEB) | Phase 4 | Not yet recruiting | Abeona Therapeutics, Inc | 100 | 2026-11-01 | 2026-08-06 |
| Emerging Indications for Hyperbaric Oxygen Treatment Hyperbaric oxygen treatment (HBOT), 100% Oxygen - Post-COVID-19 Condition, Ulcerative Colitis | Phase 4 | Not yet recruiting | Jay C. Buckey Jr. | 100 | 2026-11-01 | 2026-09-09 |
| Evaluation of the Role of Serum Tenascin-X Levels in the Diagnosis of Hypermobile Ehlers-Danlos Syndrome Blood sampling - Ehlers-Danlos Syndromes (EDS) | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 80 | 2026-11-01 | 2026-10-27 |
| CLINICAL AND BIOLOGICAL DATABASE OF PATIENTS WITH NON-VASCULAR EHLERS-DANLOS SYNDROMES Ehlers-Danlos Syndromes (EDS) | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 3500 | 2026-11-01 | 2026-10-27 | |
| A Study to Evaluate ENERGI-F703EB Cream in Epidermolysis Bullosa ENERGI-F703EB Cream, Matched vehicle cream - Epidermolysis Bullosa (EB), Junctional Epidermolysis Bullosa | Phase 2 | Recruiting | Energenesis Biomedical Co., Ltd. | 24 | 2026-10-08 | 2026-10-05 |
| The Ultrasound-Guided Dextrose Prolotherapy in Ehlers-Danlos Syndrome Patients Dextrose 50% Intravenous Solution, Lidocaine 1% Injectable Solution - Ehlers-Danlos Syndrome, Low Back Pain | Phase 3 | Withdrawn | Tulane University | 2026-10-05 | 2026-10-08 | |
| Filsuvez in Moderate-to-Severe Epidermolysis Bullosa Simplex Filsuvez - Epidermolysis Bullosa Simplex | Phase 2 | Not yet recruiting | Stanford University | 10 | 2026-10-01 | 2026-08-10 |
| COG+OT Telerehabilitation for Adults With Subjective Cognitive Complaints COG+OT Telerehabilitation - Subjective Cognitive Complaints, Ehlers-Danlos Syndrome | Not applicable | Not yet recruiting | Medical University of South Carolina | 16 | 2026-10-01 | 2026-09-21 |
| Acupuncture Combined With Transcutaneous Electrical Acupoint Stimulation for Constipation-Predominant Irritable Bowel Syndrome With Anxiety State Acupuncture, Transcutaneous Electrical Acupoint Stimulation, Sham Transcutaneous Electrical Acupoint Stimulation - IBS, Constipation Predominant, Anxiety State | Not applicable | Not yet recruiting | The First Affiliated Hospital of Zhejiang Chinese Medical University | 58 | 2026-10-01 | 2026-10-28 |
| Neurocutaneous Syndromes in Children: Prevalence and Clinical Characteristics Sturge-Weber Syndrome, Neurocutaneous Syndromes | Not yet recruiting | Assiut University | 100 | 2026-09-20 | 2026-09-28 | |
| Patient Study to Evaluate the Safety and Emollient Performance of Doublebase Once in the Treatment of Ichthyosis Doublebase Once - Ichthyosis | Not applicable | Not yet recruiting | Dermal Laboratories Ltd | 100 | 2026-09-07 | 2026-09-08 |
| Impact of Body Positioning on EndoFLIP Measurements: A Comparative Study of Supine and Left Lateral Decubitus Positions EndoFlip - Dysphagia, Esophageal Stricture | Not applicable | Recruiting | Johns Hopkins University | 25 | 2026-07-24 | 2026-08-24 |
| Efficacy and Safety Study to Evaluate SD-101 in Epidermolysis Bullosa SD-101 Dermal Cream (6%), Vehicle (SD-101 0%) - Epidermolysis Bullosa (EB) | Phase 3 | Recruiting | Paradigm Therapeutics | 80 | 2026-07-21 | 2026-10-15 |
| STABLE Pilates for Hypermobility Pilates, Education - Ehlers-Danlos Syndrome (EDS), Hypermobile EDS (hEDS) | Not applicable | Recruiting | Brigham and Women's Hospital | 100 | 2026-07-09 | 2026-08-19 |
Showing 20 of 527. Sign in to see all of them.
Epidermolysis Bullosa (80) · Epidermolysis Bullosa Dystrophica (77) · Ehlers-Danlos Syndrome (66) · Port-Wine Stain (45) · Pseudoxanthoma Elasticum (32) · Ichthyosis (30) · Ichthyosis Bullosa of Siemens (24) · Dyskeratosis Congenita (22) · Netherton Syndrome (22) · Ectodermal Dysplasia 1, Anhidrotic (21) · Epidermolysis Bullosa Simplex (20) · Irritable Bowel Syndrome (19) · Skin Diseases (18) · Ehlers-Danlos Syndrome, Type IV (16)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (521) · Skin and Connective Tissue Diseases (519) · Congenital Abnormalities (515) · Skin Diseases (502) · Genetic Diseases, Inborn (418) · Skin Diseases, Genetic (413) · Connective Tissue Diseases (205) · Collagen Diseases (153) · Skin Diseases, Vesiculobullous (145) · Hemic and Lymphatic Diseases (140) · Hematologic Diseases (137) · Cardiovascular Diseases (135) · Vascular Diseases (128) · Hemorrhagic Disorders (117)
fludarabine (10) · fludarabine phosphate (9) · Lasers, Dye (8) · Alemtuzumab (7) · Cyclophosphamide (7) · Whole-Body Irradiation (7) · Blood Specimen Collection (6) · Gentamicins (6) · Antilymphocyte Serum (5) · Surveys and Questionnaires (5) · Tacrolimus (5) · Busulfan (4) · Mycophenolic Acid (4) · diacerein (4) · thymoglobulin (4)
Assistance Publique - Hôpitaux de Paris (17) · University of California, Irvine (17) · Centre Hospitalier Universitaire de Nice (13) · Edimer Pharmaceuticals (13) · Northwestern University (11) · Stanford University (10) · University Hospital, Angers (10) · National Cancer Institute (NCI) (9) · Krystal Biotech, Inc. (7) · Masonic Cancer Center, University of Minnesota (7) · University Hospital, Toulouse (7) · Abeona Therapeutics, Inc (5) · Daiichi Sankyo (5) · Gyroscope Therapeutics Limited (5) · Institut National de la Santé Et de la Recherche Médicale, France (5)
United States (267) · France (99) · Germany (41) · United Kingdom (39) · Spain (28) · Italy (23) · Canada (21) · Netherlands (19) · Australia (17) · Austria (15) · China (12) · Israel (12) · Switzerland (11) · Poland (10) · Denmark (7)
Dorothy K Grange, MD (6) · Amy Paller, MD (5) · Holm Schneider, MD (5) · Christine Bodemer, MD, PhD (3) · Elena Pope, MD (3) · Jakub Tolar, MD, PhD (3) · Jean Tang, MD, PhD (3) · Mary Spellman, MD (3) · Adeline Vanderver, MD (2) · Alfred Lane, MD (2) · Alfred T Lane (2) · Amy Paller (2) · Amy S Paller, MD (2)
PMID 20825986, PMID 31541747, PMID 35234826, PMID 37314061, PMID 10973256, PMID 11511292, PMID 11740200, PMID 11912510, PMID 12578222, PMID 12648223, PMID 12999819, PMID 14734878, PMID 15238912, PMID 15894595, PMID 16250204, PMID 16756677, PMID 17546030, PMID 18571597, PMID 18948357, PMID 19043850, PMID 19241467, PMID 19267394, PMID 19638214, PMID 19699898, PMID 20083693, PMID 20383216, PMID 20466177, PMID 20691689, PMID 20818854, PMID 21430705, PMID 21646941, PMID 21704964, PMID 21877134, PMID 21982653, PMID 22104675, PMID 22152229, PMID 22154461, PMID 22244840, PMID 22264670, PMID 22517769, PMID 23444191, PMID 23455486, PMID 23483391, PMID 23553579, PMID 23630948, PMID 23651789, PMID 24102348, PMID 24277820, PMID 24329107, PMID 24456419
2014 (3), 2016 (2), 2017 (2), 2019 (2), P30CA015704 (2), R44CA221591 (2), UL1RR024150 (2), 1OT2OD028183-01 (1), 1RC1DK086182 (1), 2008 (1), 2015 (1), 2018 (1), 2023 (1), 2025 (1), 268201000048C-5-0-1 (1)