65 completed, 24 unknown, 9 recruiting, 9 terminated. 79 Not applicable, 16 Phase 2, 9 Phase 4, 6 Phase 3, 4 Phase 1.
Follow Colic: new trials by email Literature Review of Colic trials Research Report on Colic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Acupuncture in Infantile Colic - A Randomised Trial. Acupuncture - Infant, Newborn, Diseases, Colic, Infantile | Not applicable | Withdrawn | Region Skane | 2050-12-01 | 2026-02-17 | |
| The Effect of Probiotics in Infantile Colic Probiotic: L. reuteri total 2 × 10⁸ CFU/day, Placebo: matching oil formulation without L. reuteri - Infantile Colic | Not applicable | Recruiting | Federico II University | 50 | 2026-09-23 | 2026-11-09 |
| Use of Bifidobacterium Bifidum in Formula-Fed Infants With Colic, With or Without Atopic Dermatitis Bifidobacterium bifidum BFP19® and BFP29® (Bifipral®), Placebo - Infant Colic, Atopic Dermatitis | Not applicable | Recruiting | University of Roma La Sapienza | 64 | 2026-07-01 | 2026-08-10 |
| Preventive Effect of a Dietary Supplement With Two Probiotic Limosilactobacillus Reuteri Strains on Excessive Crying and Colic in Healthy Newborns. Two probiotic Limosilactobacillus reuteri strains, Placebo - Colic, Healthy Infants | Not applicable | Recruiting | Universitair Ziekenhuis Brussel | 768 | 2026-01-31 | 2026-02-19 |
| BioAmicus Complete for Functional Gastrointestinal Symptoms in Infants Aged 0 to 24 Months BioAmicus Complete, Usual Care (No Probiotic) - Infantile Colic, Gastroesophageal Reflux (GER) | Not applicable | Recruiting | Haiphong University of Medicine and Pharmacy | 110 | 2025-09-05 | 2026-01-29 |
| Validation Of A Parent Administered Symptom Score For Unsettled Infants (Every Baby is UnIQue) Online parent administered questionnaire - Colic, Infantile, Milk Allergy, Cow's | Not yet recruiting | University Hospital Southampton NHS Foundation Trust | 350 | 2025-09-01 | 2025-08-13 | |
| Evaluating the Effect of Probiotic Limosilactobacillus Reuteri (L. Reuteri) on Crying and Fussing Time in Infants With Colic L. reuteri, Placebo - Infantile Colic | Not applicable | Active not recruiting | BioGaia AB | 50 | 2025-08-04 | 2026-10-15 |
| Effect of a Dietary Supplement vs Low-dosage Product on Infant Gastrointestinal Discomfort and Colics Verum, Active comparator - Infant Colic, Gut Microbiota | Not applicable | Not yet recruiting | Azienda Ospedaliera Universitaria Policlinico "G. Martino" | 150 | 2025-06-15 | 2025-06-12 |
| Effect of Probiotic Limosilactobacillus Reuteri (L. Reuteri) on Crying and Fussing Time in Infants With Colic L. reuteri, Placebo - Infantile Colic | Not applicable | Completed | BioGaia AB | 50 | 2025-06-09 | 2026-03-19 |
| Vimala Massage Infantile Colic, Sleep and Development Levels Vimala Massage Training for Fathers, Control Intervention, Vimala Massage Training for Mothers - Massage Effect | Not applicable | Not yet recruiting | Kilis 7 Aralik University | 72 | 2025-06-01 | 2025-05-29 |
| The Effect of Cranial Osteopathy Intervention in Preterm Babies Osteopathic intervention, Home based exercise education - Osteopathy, PreTerm Neonate | Not applicable | Not yet recruiting | Abant Izzet Baysal University | 30 | 2025-05-05 | 2025-05-13 |
| The Effect of Thermal Heat Application on Colic in Infants Cherry Pit Pillow Application, Warm Towel Application - Infantile Colics | Not applicable | Completed | Istanbul University - Cerrahpasa | 75 | 2025-04-15 | 2026-02-27 |
| Investigation of the Development of Infants With a History of Colic Peabody Developmental Motor Scales-2, Test Of Sensory Functions In Infants (Tsfı), Brief Infant Sleep Questionnaire - Colic, Infantile, Motor Development | Completed | Nigde Omer Halisdemir University | 46 | 2025-03-12 | 2025-06-26 | |
| 0-3 Months Infantile Colic The Effect of Ocean Sound on Babies ocean sound concert - Infantile Colic | Not applicable | Not yet recruiting | Zonguldak Bulent Ecevit University | 60 | 2024-12-15 | 2024-12-20 |
| RELIEF-pathway in Patients With Upper Abdominal Pain RELIEF-pathway - Abdominal Pain, Gallstone; Colic | Not applicable | Active not recruiting | Radboud University Medical Center | 471 | 2024-11-01 | 2026-09-09 |
| Evolution of Functional Gastrointestinal Disorders in Infants Fed With a New Infant Formula New infant formula - Functional Gastrointestinal Disorders | Not applicable | Recruiting | United Pharmaceuticals | 139 | 2024-10-21 | 2025-01-06 |
| Effect of Probiotics on Infantile Colic Symptoms Probiotic, Placebo - Infantile Colic | Phase 2 | Recruiting | Lallemand Health Solutions | 70 | 2024-08-01 | 2024-08-16 |
| The Effects of Reiki Therapy in Infants With Colic Reiki - Reiki, Colic, Infantile | Not applicable | Completed | University of Yalova | 44 | 2024-07-01 | 2026-05-29 |
| The BEGIN Study Bifidobacterium Infantis to Newborns: Effects of Modulating the Gut Microbial Composition on Growth, Immune Function and Inflammatory Conditions - a Randomized Placebo-controlled Double-blinded Intervention Trial B. infantis, Placebo - Healthy, Healthy Nutrition | Not applicable | Recruiting | University of Aarhus | 1000 | 2024-06-10 | 2024-10-01 |
| A Randomized Controlled Trial Comparing Fat-free Versus Balanced (WHO) Diet in Gallstone Disease Fat-free diet, Balanced WHO diet - Gallstone Disease, Gallstone; Colic | Not applicable | Unknown | University Hospital of Crete | 242 | 2024-03-27 | 2024-05-09 |
Showing 20 of 121. Sign in to see all of them.
Crying (12) · Gastroesophageal Reflux (8) · Gastrointestinal Diseases (8) · Constipation (7) · Abdominal Pain (4) · Breast Feeding (4) · Depression, Postpartum (4) · Gallstones (4) · Dermatitis, Atopic (3) · Cholelithiasis (2) · Diarrhea (2) · Inflammation (2) · Kidney Calculi (2) · Pain (2)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (121) · Infant, Newborn, Diseases (120) · Pathological Conditions, Signs and Symptoms (25) · Behavior (18) · Digestive System Diseases (18) · Signs and Symptoms (15) · Communication (12) · Nonverbal Communication (12) · Signs and Symptoms, Digestive (11) · Female Urogenital Diseases and Pregnancy Complications (9) · Urogenital Diseases (9) · Deglutition Disorders (8) · Esophageal Diseases (8) · Esophageal Motility Disorders (8) · Neurologic Manifestations (8)
Acupuncture Therapy (4) · MEN 11420 (4) · Probiotics (4) · Therapeutic Touch (4) · Butylscopolammonium Bromide (2) · Control Groups (2) · Massage (2) · Simethicone (2) · Sunflower Oil (2) · Ampicillin (1) · Baclofen (1) · Chamomile extract (1) · Cholecalciferol (1) · Counseling (1) · Diclofenac (1)
BioGaia AB (5) · Federico II University (4) · Menarini Group (4) · The University of Texas Health Science Center, Houston (4) · Karamanoğlu Mehmetbey University (3) · AB Biotics, SA (2) · European School of Osteopathy (2) · Lallemand Health Solutions (2) · Lund University (2) · Nordic Institute of Chiropractic and Clinical Biomechanics (2) · Société des Produits Nestlé (SPN) (2) · The Hospital for Sick Children (2) · The President Stanisław Wojciechowski State University of Applied Sciences in Kalisz (2) · University of Seville (2) · Abant Izzet Baysal University (1)
Italy (18) · United States (17) · Turkey (Türkiye) (15) · France (8) · Spain (8) · United Kingdom (6) · Canada (5) · Sweden (5) · Poland (4) · Denmark (3) · Mexico (3) · Thailand (3) · Belgium (2) · Germany (2) · India (2)
Hanna Krauss, Prof. (2) · J. Marc Rhoads, M.D. (2) · Badriul Hegar, MD, PhD (1) · Barbro Hedin Skogman, assoc. prof. (1) · Bryan M Harvey, M.D. (1) · Camille Jung, Prof. (1) · Christophe Batard, Dr. (1) · Christophe Dupont, PhD (1) · Cornelis van Laarhoven, MD PhD (1) · Diane Krieger, MD (1)
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K23HD065872 (1), R01MH077683 (1), R21AT003519 (1), U01AT003519 (1)