36 completed, 12 unknown, 6 not yet recruiting, 2 terminated. 51 Not applicable, 4 Phase 2, 4 Phase 3, 2 Phase 4, 1 Phase 1.
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Limosilactobacillus Reuteri on Social Deficits in Children With Autistic Spectrum Disorder Probiotics, Placebo - Autism Spectrum Disorder | Not applicable | Not yet recruiting | BioGaia AB | 200 | 2026-10-15 | 2026-09-30 |
| Probiotics for Sustained Health Probiotic, Placebo - Upper Respiratory Tract Infection (URTI) | Not applicable | Not yet recruiting | BioGaia AB | 70 | 2026-09-25 | 2026-09-24 |
| An Open-label, Single-arm Interventional Study to Evaluate the Safety and Efficacy of a Probiotic-containing Cream in Children With Dry Skin Probiotic Ointment - Dry Skin | Not applicable | Not yet recruiting | BioGaia AB | 40 | 2026-09-01 | 2026-07-20 |
| Efficacy and Tolerability of a Probiotic Ointment Probiotic Ointment, Comparator product - Atopic Dermatitis | Not applicable | Not yet recruiting | BioGaia AB | 92 | 2026-08-01 | 2026-07-15 |
| Influence of Probiotics on Early Gut Microbial Colonization Probiotic drops, Placebo drops - C-Section | Not applicable | Not yet recruiting | BioGaia AB | 150 | 2026-08-01 | 2026-05-27 |
| Preventive Effect of a Dietary Supplement With Two Probiotic Limosilactobacillus Reuteri Strains on Excessive Crying and Colic in Healthy Newborns. Two probiotic Limosilactobacillus reuteri strains, Placebo - Colic, Healthy Infants | Not applicable | Recruiting | Universitair Ziekenhuis Brussel | 768 | 2026-01-31 | 2026-02-19 |
| Evaluating the Effect of Probiotic Limosilactobacillus Reuteri (L. Reuteri) on Crying and Fussing Time in Infants With Colic L. reuteri, Placebo - Infantile Colic | Not applicable | Active not recruiting | BioGaia AB | 50 | 2025-08-04 | 2026-10-15 |
| Effect of Probiotic Limosilactobacillus Reuteri (L. Reuteri) on Crying and Fussing Time in Infants With Colic L. reuteri, Placebo - Infantile Colic | Not applicable | Completed | BioGaia AB | 50 | 2025-06-09 | 2026-03-19 |
| Effects of Probiotic Oral Intake on Plasma Chlordecone (Kepone) Concentrations in Individuals Environmentally Exposed to Pesticide in Martinique. Limosilactobacillus reuteri, Placebo - Chlordecone (Kepone) Toxicity | Not applicable | Not yet recruiting | University Hospital Center of Martinique | 100 | 2024-04-01 | 2024-02-21 |
| Effect of Probiotic Limosilactobacillus Reuteri (L. Reuteri) on Crying Time in Infants With Colic L. reuteri, Placebo - Colic, Infantile | Not applicable | Completed | BioGaia AB | 102 | 2022-07-13 | 2026-10-15 |
| Prevention of Glucocorticoid Induced Impairment of Bone Metabolism Lactobacillus reuteri ATCC PTA 6475 (L. reuteri 6475), Prednisolone - Bone Loss | Not applicable | Completed | Sahlgrenska University Hospital | 50 | 2022-05-16 | 2023-02-06 |
| The Use of Chlorhexidine and a Probiotic Lozenge in the Nonsurgical Therapy of Periodontitis active chlorhexidine and placebo probiotic, placebo chlorhexidine and active probiotic, active chlorhexidine and active probiotic - Periodontitis, Chlorhexidine | Not applicable | Completed | Cukurova University | 90 | 2022-04-01 | 2025-06-15 |
| Study Evaluating the Safety and Tolerability of a Probioitc Probiotic, Placebo - Healthy Volunteers, Tolerability | Not applicable | Completed | BioGaia AB | 35 | 2021-11-01 | 2022-02-11 |
| Validation of Active-Insights Device to Measure Crying Time ActiveInsights accelerometer device - Infant Behavior | Not applicable | Unknown | BioGaia AB | 13 | 2021-10-15 | 2021-12-21 |
| The Effect of Probiotic Lactobacillus Reuteri Prodentis Consumption on Gingival Crevicular Fluid Inflammatory Response and Metagenomic Profiles of Oral Microbiome in Orthodontic Patients. BioGaia Probiotic Lozenges - Healthy Subjects With Fixed Orthodontics | Not applicable | Unknown | Trisakti University | 20 | 2021-03-22 | 2022-11-14 |
| Study Evaluating the Safety and Tolerability Probiotic - Healthy Volunteers | Not applicable | Completed | BioGaia AB | 36 | 2021-01-05 | 2021-06-18 |
| The Effect of Probiotic Supplementation on SARS-CoV-2 Antibody Response After COVID-19 L. reuteri DSM 17938 + vitamin D, Placebo + vitamin D - Covid19 | Not applicable | Completed | Örebro University, Sweden | 161 | 2020-11-27 | 2021-10-15 |
| Influence of Probiotics on Clinical Parameters, the Oral Microbiome and the Immune System During an Orthodontic Treatment Lactobacillus reuteri Prodentis®-lozenges (DSM 17938, ATCC PTA 5289), Placebo-lozenges (BioGaia) - Gingivitis, Orthodontic Appliance Complication | Not applicable | Unknown | University of Erlangen-Nürnberg | 34 | 2020-11-24 | 2022-05-18 |
| Effect of Probiotics on Testosterone in Men Lactobacillus reuteri (L. reuteri) - Healthy | Not applicable | Completed | BioGaia AB | 60 | 2020-11-05 | 2021-06-21 |
| Influence of Probiotics on Clinical Parameters, the Oral Microbiome and the Immune System During an Orthodontic Treatment in Adult Patients Lactobacillus reuteri Prodentis®-lozenges (DSM 17938, ATCC PTA 5289), Placebo-lozenges (BioGaia) - Gingivitis, Periodontal Inflammation | Not applicable | Unknown | University of Erlangen-Nürnberg | 34 | 2020-10-19 | 2022-05-18 |
Showing 20 of 60. Sign in to see all of them.
Colic (7) · Constipation (5) · Abdominal Pain (3) · Dermatitis, Atopic (3) · Diarrhea (3) · Dyspepsia (3) · Inflammation (3) · Periodontitis (3) · Body Weight (2) · Bone Diseases, Metabolic (2) · Crying (2) · Gastroenteritis (2) · Gingivitis (2) · Anorexia Nervosa (1) · Autism Spectrum Disorder (1)
Probiotics (12) · Rapid Diagnostic Tests (2) · Amoxicillin (1) · Anti-Bacterial Agents (1) · Clarithromycin (1) · Ointments (1) · Omeprazole (1) · Prednisolone (1) · Vitamin D (1) · World Health Organization oral rehydration solution (1) · Zinc Sulfate (1)
Sweden (18) · Mexico (8) · Italy (4) · Belgium (3) · Croatia (3) · Botswana (2) · France (2) · Germany (2) · Greece (2) · Indonesia (2) · Ireland (2) · Argentina (1) · Bulgaria (1) · Canada (1) · Chile (1)
Erik Rein-Hedin, MD (3) · Mattias Lorentzon, MD, PhD (3) · Corinna Lesley Seidel, Dr. (2) · Jeffrey Pernica, MD (2) · Alexandra Papadopoulou, Dr (1) · Alexandra Papadopoulou, Hon. Prof. Dr. med. (1) · Alison L Steiber, PhD, RD, LD (1) · Armelia Sari Widyarman, Ph.D (1) · Badriul Hegar, MD, PhD (1) · Bo Jacobsson, Professor (1) · Burgert Jaques Van Wyk, MB, ChB (1) · Chaminda Jayampath Seneviratne, Ph.D (1) · Citra Fragnantia Theodora, Ph.D (1)
PMID 35477563, PMID 11921380, PMID 12848475, PMID 16187156, PMID 16205524, PMID 16878680, PMID 17349686, PMID 18221472, PMID 18281199, PMID 18461650, PMID 19091823, PMID 19285652, PMID 19525871, PMID 19682173, PMID 20980489, PMID 21157050, PMID 21292654, PMID 21448219, PMID 21801246, PMID 21821542, PMID 21888302, PMID 22010614, PMID 22153774, PMID 22694350, PMID 22916296, PMID 23092239, PMID 23517039, PMID 23902407, PMID 23926244, PMID 24034345, PMID 24296746, PMID 24330256, PMID 24638207, PMID 24848255, PMID 24948349, PMID 25002964, PMID 25748731, PMID 25780308, PMID 26255208, PMID 27296254, PMID 27590374, PMID 27612653, PMID 27906800, PMID 2927852, PMID 30134331, PMID 33763652, PMID 33923278, PMID 34192396, PMID 34857236, PMID 35418412