10 completed, 3 unknown, 2 withdrawn, 1 recruiting. 16 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 16 | Completed 10, Unknown 3, Withdrawn 2, Recruiting 1 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
Follow Colic: new trials by email Literature Review of Colic trials Research Report on Colic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Probiotics on Infantile Colic Symptoms Probiotic, Placebo - Infantile Colic | Phase 2 | Recruiting | Lallemand Health Solutions | 70 | 2024-08-01 | 2024-08-16 |
| Probiotics Strains for Infant Colic Placebo, Limosilactobacillus reuteri CCT 7862, Bifidobacterium lactis CCT 7858 + Lactobacillus rhamnosus CCT 7863 - Colic | Phase 2 | Unknown | Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude | 180 | 2023-01-05 | 2023-01-13 |
| The Effect of Probiotics on Symptoms of Infantile Colic Probiotic Formulation, Placebo - Colic | Phase 2 | Withdrawn | Lallemand Health Solutions | 2022-02-08 | 2023-07-03 | |
| Effects of Vivatlac Baby on Crying Behavior of Colicky Babies Simethicone Solution, Vivatlac Baby - Infantile Colic | Phase 2 | Completed | The President Stanisław Wojciechowski State University of Applied Sciences in Kalisz | 87 | 2020-04-16 | 2023-11-22 |
| Infant Colic Treatment With Probiotics B. breve, B. breve plus L. fermentum, Simethicone 20 MG - Infant Colic | Phase 2 | Completed | Mónica Olivares Martín; PhD | 156 | 2017-05-31 | 2019-07-23 |
| Prevention of Colic With the Probiotic Lactobacillus Reuteri Lactobacillus reuteri DSM 17938, Placebo - Colic | Phase 2 / Phase 3 | Unknown | Hospital General Naval de Alta Especialidad - Escuela Medico Naval | 478 | 2015-10-01 | 2015-10-16 |
| Treatment of Suspected Cholelithiasis With Nitroglycerin sublingual nitroglycerine - COLIC, BILIARY TRACT DISEASES | Phase 2 | Unknown | United States Naval Medical Center, San Diego | 62 | 2014-10-01 | 2017-09-29 |
| Peritoneal Ropivacaine Infiltration on Postoperative Pain in Children Affected intraperitoneal infiltration of ropivacaine - Testicular, Colic | Phase 2 | Completed | Ping Yang | 70 | 2013-11-01 | 2015-03-26 |
| Acupuncture in Infantile Colic - a Three Armed Randomized Multi Center Trial (ACU-COL) Acupuncture - Infantile Colic | Phase 2 / Phase 3 | Completed | Lund University | 147 | 2013-01-01 | 2016-06-28 |
| Lactobacillus Reuteri DSM 17938 Versus Placebo in the Treatment of Infantile Colic Biogaia L. reuteri DSM 17938, Probiotic Placebo - Colic | Phase 2 | Completed | The Hospital for Sick Children | 55 | 2011-11-01 | 2014-11-20 |
| Preliminary Efficacy, Safety and Pharmacokinetics Study of Nepadutant in Infant With Feeding Intolerance Nepadutant - Colic | Phase 2 | Completed | Menarini Group | 27 | 2011-08-01 | 2023-05-06 |
| Preliminary Efficacy and Safety Study of Oral Nepadutant in Infant With Colic Not Responding to Conventional Treatment Nepadutant oral solution, Placebo matching Nepadutant oral solution - Infantile Colic | Phase 2 | Withdrawn | Menarini Group | 2011-02-01 | 2012-11-06 | |
| Preliminary Efficacy and Safety Study of Oral Nepadutant in Infant Colic Nepadutant oral solution, Placebo matching Nepadutant oral solution - Infantile Colic | Phase 2 | Completed | Menarini Group | 115 | 2010-11-01 | 2015-06-10 |
| Effects of Acupuncture in the Treatment of Infant Colic Acupuncture with Seirin 020x15 mm sterile acupuncture needle - Infant Colic | Phase 2 | Completed | University of Oslo | 90 | 2009-09-01 | 2015-03-17 |
| Study to Evaluate Efficacy and Safety of Oral Doses of Hyoscine Butylbromide for the Treatment of Occasional Abdominal Pain, Cramping, and Discomfort Hyoscine butylbromide, Placebo - Colic | Phase 2 | Completed | Boehringer Ingelheim | 527 | 2006-04-01 | 2017-12-28 |
| Parents Helping Infants Study: Educational Intervention to Change the Knowledge, Attitudes and Behaviour of New Parents About Early Infant Crying The Period of PURPLE Crying Program - Shaken Baby Syndrome | Phase 1 / Phase 2 | Completed | University of British Columbia | 1833 | 2005-05-01 | 2010-12-17 |
Crying (2) · Abdominal Pain (1) · Agnosia (1) · Biliary Tract Diseases (1) · Cholelithiasis (1) · Health Education (1) · Pain (1) · Shaken Baby Syndrome (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (16) · Infant, Newborn, Diseases (16) · Behavior (2) · Communication (2) · Nervous System Diseases (2) · Neurologic Manifestations (2) · Nonverbal Communication (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Adherence Interventions (1) · Brain Injuries (1) · Craniocerebral Trauma (1) · Digestive System Diseases (1) · Health Behavior (1) · Medication Adherence (1)
MEN 11420 (3) · Acupuncture Therapy (2) · Simethicone (2) · Butylscopolammonium Bromide (1) · Nitroglycerin (1) · Probiotics (1)
Menarini Group (3) · Lallemand Health Solutions (2) · Boehringer Ingelheim (1) · Hospital General Naval de Alta Especialidad - Escuela Medico Naval (1) · Lund University (1) · Mónica Olivares Martín; PhD (1) · Ping Yang (1) · The Hospital for Sick Children (1) · The President Stanisław Wojciechowski State University of Applied Sciences in Kalisz (1) · United States Naval Medical Center, San Diego (1) · Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude (1) · University of British Columbia (1) · University of Oslo (1)
Canada (2) · Poland (2) · Spain (2) · Sweden (2) · United States (2) · Brazil (1) · China (1) · France (1) · Germany (1) · Norway (1) · Russia (1)
Gideon Koren, MD (1) · Hanna Krauss, Prof. (1) · Holgeir Skjeie, MD (1) · Jeffrey L Blumer, MD, PhD (1) · Kajsa Landgren, PhD (1) · Paolo Lionetti, MD (1) · Pr. Nicholas Kalach, MD (1) · Ronald G Barr, MD (1) · Sibylle Koletzko, MD (1) · Steven J Portouw, MD (1) · Yang Hui, Professor (1)
PMID 19255065, PMID 21450707, PMID 24228748, PMID 25444531, PMID 26370560, PMID 28093383, PMID 32375501, PMID 33765904