12 completed, 4 unknown, 1 recruiting, 1 terminated. 12 Not applicable, 2 Phase 3, 2 Phase 4, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 12 | Completed 9, Recruiting 1, Terminated 1, Unknown 1 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
| Phase 4 | 2 | Completed 2 |
| Phase 1 | 1 | Unknown 1 |
| Phase 2 | 1 | Unknown 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Impact of Valerian and Chamomile on Children's Anxiety in the Dental Clinic Valerian extract, Chamomile extract, Water (Placebo) - Anxiety, Dental | Not applicable | Completed | Damascus University | 78 | 2025-12-01 | 2026-09-01 |
| Efficacy of JAK STAT Pathways Inhibitors in Treatment of Patients With Rheumatoid Arthritis Green Tea Polyphenolics (EGCG), Chamomile (Matricaria recutita), Licorice - Rheumatoid Arthritis | Not applicable | Completed | Adel A.Gomaa | 60 | 2025-04-05 | 2026-10-26 |
| Effects of Chamomile With L-theanine Beverage Among Young Women Experiencing Primary Dysmenorrhea Chamomile (Matricaria recutita), Chamomile - Primary Dysmenorrhea | Not applicable | Recruiting | Universiti Tunku Abdul Rahman | 30 | 2025-03-01 | 2025-07-30 |
| Low Level Diode Laser Versus Topical Chamomile in Management of Chemotherapy Induced Oral Mucositis Low level diode laser, Chamomile, Ibuprofen analgesic and anti-inflammatory oral gel and miconazole anti fungal oral gel - Chemotherapy Induced Oral Mucositis | Phase 2 | Unknown | Cairo University | 45 | 2024-04-01 | 2024-01-23 |
| The Effect of Pomegranate Peel, German Chamomile or Their Combination on Gingivitis Chamomile extract mouthwash, Pomegranate peel extract mouth wash, Combination of 5% chamomile extract and pomegranate peel extract mouthwash - Gingivitis | Phase 3 | Unknown | Alexandria University | 60 | 2023-07-11 | 2023-07-19 |
| Chamomile Effect on Xerostomia Associated With End-stage Renal Disease in Elderly Chamomile, Saline mouthwash - Xerostomia Due to Hyposecretion of Salivary Gland | Not applicable | Completed | Ain Shams University | 88 | 2023-07-01 | 2024-08-27 |
| Effectiveness of a Cream for Treatment of Dermatitis in Patients Whith Breast Cancer Cosmetic cream (Alantel (R): aloe vera, chamomile and thime), Usual treatment - DERMATITIS INDUCED BY RADIOTHERAPY IN PATIENTS WHITH BREAST CANCER | Not applicable | Completed | Hospital Universitario Reina Sofia de Cordoba | 78 | 2022-07-19 | 2024-02-05 |
| Role of Saffron and Chamomile in the Management of Parkinson's Disease conventional therapy, Saffron and Chamomile, Crocin and Apigenin - Parkinson Disease, Neurodegenerative Diseases | Not applicable | Unknown | Jinnah Postgraduate Medical Centre | 120 | 2022-07-05 | 2023-01-25 |
| The Acute Effects of Chamomile Intake on Blood Coagulation Tests in Healthy Volunteers Chamomile Tea, Chamomile Extract Capsule - Coagulation Disorder | Not applicable | Completed | Stony Brook University | 8 | 2022-03-16 | 2022-06-10 |
| Effect of Chamomile Intake on Blood Coagulation Tests in Healthy Volunteers Chamomile Tea, Chamomile Extract Capsule, Placebo Capsule - Coagulation Disorder | Not applicable | Completed | Stony Brook University | 12 | 2021-08-31 | 2022-02-10 |
| Evaluation of Topical Chamomile Versus Topical Triamcinolone Acetonide in Management of Oral Lichen Planus topical chamomile - Oral Lichen Planus | Phase 1 | Unknown | Cairo University | 37 | 2019-01-15 | 2019-01-04 |
| TTO Swabs Versus Baby Shampoo in Patients With Seborrehic Blepharitis Swabs containing tea tree oil and chamomile oil, Baby shampoo - Seborrheic Blepharitis | Phase 4 | Completed | Istanbul University - Cerrahpasa | 49 | 2018-11-12 | 2020-12-22 |
| Comparative Analysis of Chamomile Tea (Matricaria Chamomilla) and Green Tea (Camellia Sinensis) Against Hyperlipidemia Chamomile tea (Matricaria chamomilla), Green tea (Camellia sinensis), Chamomile tea and Green tea combined - Hyperlipidemia, Normal | Not applicable | Completed | Iahtisham-Ul-Haq | 25 | 2018-11-12 | 2026-10-30 |
| Infantile Colic: Study of the Efficacy of Lactobacillus GG (ATCC 53103) Plus Chamomile in Breastfeeding Infants chamomile/probiotic arm, Placebo of chamomile/probiotic arm - Infantile Colic | Not applicable | Terminated | University of Nebraska | 1 | 2018-05-18 | 2023-08-25 |
| Absorption, Metabolism and Excretion of Apigenin and Apigenin Glycosides Chamomile Tea, Parsley based drink, Parsley Yogurt - Healthy | Not applicable | Completed | University of California, Davis | 17 | 2015-01-20 | 2019-05-23 |
| Long Term Chamomile Therapy for Anxiety Chamomile (Matricaria recutita) - Generalized Anxiety Disorder | Phase 3 | Completed | University of Pennsylvania | 180 | 2010-02-01 | 2017-07-06 |
| Chamomile Therapy for Generalized Anxiety Chamomile Extract, Placebo - Generalized Anxiety Disorder | Phase 4 | Completed | University of Pennsylvania | 61 | 2005-10-01 | 2009-12-02 |
| Treatment of Functional Abdominal Pain in Children: Evaluation of Relaxation/Guided Imagery and Chamomile Tea as Therapeutic Modalities chamomile tea, Relaxation/Guided Imagery - Recurrent Abdominal Pain | Not applicable | Completed | National Center for Complementary and Integrative Health (NCCIH) | 1998-09-01 | 2006-08-18 |
Anxiety Disorders (3) · Generalized Anxiety Disorder (2) · Hemostatic Disorders (2) · Thrombosis (2) · Abdominal Pain (1) · Arthritis, Rheumatoid (1) · Breast Neoplasms (1) · Colic (1) · Dermatitis (1) · Gingivitis (1) · Hyperlipidemias (1) · Lichen Planus, Oral (1) · Neurodegenerative Diseases (1) · Parkinson Disease (1) · Xerostomia (1)
Cairo University (2) · Stony Brook University (2) · University of Pennsylvania (2) · Adel A.Gomaa (1) · Ain Shams University (1) · Alexandria University (1) · Damascus University (1) · Hospital Universitario Reina Sofia de Cordoba (1) · Iahtisham-Ul-Haq (1) · Istanbul University - Cerrahpasa (1) · Jinnah Postgraduate Medical Centre (1) · National Center for Complementary and Integrative Health (NCCIH) (1) · Universiti Tunku Abdul Rahman (1) · University of California, Davis (1) · University of Nebraska (1)
United States (7) · Egypt (3) · Pakistan (2) · Malaysia (1) · Spain (1) · Syria (1) · Turkey (Türkiye) (1)
Adel A Gomaa, Ph.D. (1) · Carl L Keen, PhD (1) · Doaa A Ghareeb, PhD (1) · Eman Sh Anwar, PhD (1) · Fayez K. Ghishan (1) · Fizzah Ali, MBBS,MPhil (1) · Javier I Ottaviani, PhD (1) · Jay D. Amsterdam, M.D. (1) · Juman Hayo, DDS (1) · Jun J Mao, MD (1) · Maha R Taalab, PhD (1) · Marwa A Alashwah, PharmD (1) · Noha A Hamdy, PhD (1) · Ruben E Quiros, MD (1) · Safaa A Mahran, MD (1)
PMID 19593179, PMID 24904963, PMID 27706421, PMID 27716513, PMID 27912875, PMID 28389404, PMID 28951838, PMID 29080520, PMID 29147836, PMID 30159851, PMID 31111370, PMID 32062592, PMID 32920135, PMID 33290635, PMID 34224829, PMID 35274200, PMID 35452808, PMID 37730613, PMID 38273379, PMID 38300838, PMID 9145556
P50AT000008 (1), R21AT001916 (1)