37 completed, 17 unknown, 7 withdrawn, 5 terminated. 14 Not applicable, 11 Phase 2, 7 Phase 3, 4 Phase 1, 3 Phase 4.
Follow Coagulopathy: new trials by email Literature Review of Coagulopathy trials Research Report on Coagulopathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase IIb Multicenter Randomized Controlled Trial Evaluating the Efficacy of Sivelestat in Patients With Septic Coagulopathy • Sivelestat intravenous infusion, NaCl intravenous infusion - Septic Shock, Coagulopathy | Phase 2 | Not yet recruiting | University Hospital, Strasbourg, France | 120 | 2027-08-01 | 2026-08-20 |
| ROTEM Interpretation AI vs Experts Large Language Model (LLM) artificial intelligence assesment - Coagulopathy, Thromboelastography | Not yet recruiting | Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s. | 400 | 2026-09-01 | 2026-03-31 | |
| Assessment of Artificial Intelligence Algorithms for ROTEM Artificial Intelligence-Based ROTEM Interpretation - Coagulopathy | Withdrawn | Ondokuz Mayıs University | 2025-07-01 | 2026-07-02 | ||
| Association Between Hypomagnesemia and Coagulopathy in Sepsis Serum magnesium concentration - Hypomagnesemia, Coagulopathy | Completed | Ain Shams University | 150 | 2025-04-01 | 2026-05-08 | |
| A Study to Learn About How Safe BAY 3389934 is, Its Suitable Dose, and How it Affects the Participants With Sepsis Induced Coagulopathy BAY3389934 - Sepsis, Coagulopathy | Phase 1 | Recruiting | Bayer | 36 | 2025-03-12 | 2026-10-16 |
| Thromboelastography Guided Blood Product Transfusion for Upper Gastrointestinal Bleeding in Cirrhosis Thromboelastography - Cirrhosis, Liver, Coagulopathy | Not applicable | Withdrawn | Vanderbilt University Medical Center | 2025-01-16 | 2024-04-12 | |
| Frequency, Predictors and Outcome of Sepsis Induced Coagulopathy in Critical Care Unit Coagulopathy | Unknown | Assiut University | 100 | 2024-09-10 | 2024-09-19 | |
| Effects of Bothrops Spp. Snake Envenomation on Willebrand Factor Activity in Martinique and French Guiana Patients suffering from envenomation by Bothrops - Snake Envenomation, Thrombi | Unknown | University Hospital Center of Martinique | 30 | 2024-08-02 | 2024-09-26 | |
| Evaluation of TEG 6S PM® During Cardiopulmonary Bypass to Detect Postoperative Biological Coagulopathy In vitro medical diagnostic device TEG6s® Platelet Mapping - Coagulopathy, Cardiopulmonary Bypass | Completed | University Hospital, Montpellier | 60 | 2024-07-01 | 2025-03-12 | |
| Patient Blood Management Implementation in CEE Study Data collection on interventions performs as per medical routine - Anemia, Coagulopathy | Recruiting | Semmelweis University | 2000 | 2024-05-27 | 2025-03-14 | |
| Predictive Accuracy of PLR and PNR in Detecting ETIC Trauma Injury, Coagulopathy | Recruiting | Jubilee Mission Medical College and Research Institute | 250 | 2023-10-17 | 2025-07-02 | |
| Validation of Point-of-care Thromboelastography (TEG 6s) in Pediatric Patients Thromboelastography (TEG 6S) - Coagulopathy | Not applicable | Recruiting | Indiana University | 125 | 2023-09-11 | 2026-08-04 |
| FFP Usage in Pediatric CV Surgery Coagulopathy, Congenital Heart Disease | Completed | University of Alberta | 431 | 2023-08-28 | 2024-09-19 | |
| Microcirculation and Coagulopathy in Sepsis Sepsis, Coagulopathy | Completed | Università Politecnica delle Marche | 30 | 2023-06-01 | 2026-02-11 | |
| Ascending Dose Study of FrontlineODP™ Spray Dried Plasma Autologous Spray Dried Plasma - Coagulopathy, Hemorrhage | Phase 1 | Completed | Velico Medical | 24 | 2022-12-01 | 2025-09-18 |
| Fibrinogen Early In Severe Trauma StudY II Fibrinogen Concentrate, Cryoprecipitate - Trauma, Haemorrhagic Shock | Phase 3 | Completed | Australian and New Zealand Intensive Care Research Centre | 900 | 2022-11-21 | 2026-09-09 |
| Quantra vs TEG for Congenital Cardiac Surgery - a Pilot Validation Study Correlation of the Quantra with the TEG - Coagulopathy | Completed | Stanford University | 40 | 2022-10-13 | 2025-05-13 | |
| PENG Block vs FNB + ONB in Patients Undergoing Hip Fracture Surgery With Contraindications to Neuraxial Anesthesia PENG BLOCK, Femoral Nerve Block, Obturator Nerve Block - Hip Fractures, Pain, Postoperative | Not applicable | Completed | Campus Bio-Medico University | 40 | 2022-01-01 | 2024-06-14 |
| Evaluation of a Transfusion Therapy Using Whole Blood in the Management of Coagulopathy in Patients With Acute Traumatic Hemorrhage Whole blood transfusion, Fractionated blood products transfusion - Trauma, Acute Hemorrhage | Phase 3 | Completed | Direction Centrale du Service de Santé des Armées | 200 | 2021-12-04 | 2026-01-26 |
| The Utility of Camostat Mesylate in Patients With COVID-19 Associated Coagulopathy (CAC) and Cardiovascular Complications Camostat Mesylate, Microcrystalline Cellulose, NF - Coagulopathy, Cardiovascular Complication | Phase 1 / Phase 2 | Withdrawn | Yale University | 2021-11-01 | 2022-05-18 |
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Hemostatic Disorders (72) · Hemorrhage (15) · Wounds and Injuries (14) · Sepsis (6) · Disseminated Intravascular Coagulation (4) · Thrombosis (4) · COVID-19 (3) · Liver Cirrhosis (3) · Accidental Injuries (2) · Afibrinogenemia (2) · Critical Illness (2) · Multiple Trauma (2) · Shock, Septic (2) · Snake Bites (2) · Acquired Immunodeficiency Syndrome (1)
Hematologic Diseases (72) · Hemic and Lymphatic Diseases (72) · Hemorrhagic Disorders (72) · Vascular Diseases (72) · Cardiovascular Diseases (71) · Pathologic Processes (35) · Pathological Conditions, Signs and Symptoms (35) · Infections (14) · Inflammation (9) · Systemic Inflammatory Response Syndrome (8) · Blood Coagulation Disorders (7) · Respiratory Tract Diseases (6) · Wounds and Injuries (6) · Disease Attributes (5) · Embolism and Thrombosis (5)
Fibrinogen (6) · Thrombelastography (4) · cryoprecipitate coagulum (4) · Saline Solution (2) · ART123 (1) · Anti-Inflammatory Agents, Non-Steroidal (1) · Ascorbic Acid (1) · Aspirin (1) · Blood Specimen Collection (1) · Blood Transfusion (1) · Deamino Arginine Vasopressin (1) · Deoxyribonucleases (1) · Diclofenac (1) · Enoxaparin (1) · Exchange Transfusion, Whole Blood (1)
Assiut University (4) · Gold Coast Hospital and Health Service (2) · Octapharma (2) · University Health Network, Toronto (2) · University Hospital, Strasbourg, France (2) · A.O. Ospedale Papa Giovanni XXIII (1) · Ain Shams University (1) · Asahi Kasei Pharma America Corporation (1) · Australian and New Zealand Intensive Care Research Centre (1) · Bayer (1) · Bellal A. Joseph, MD, FACS (1) · Brigham and Women's Hospital (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Campus Bio-Medico University (1) · Denver Health and Hospital Authority (1)
United States (18) · France (8) · Canada (5) · Australia (4) · Germany (4) · Italy (4) · Belgium (3) · China (3) · Czechia (3) · Egypt (3) · Israel (3) · Netherlands (3) · Spain (3) · Hungary (2) · India (2)
Wolfgang Frenzel (2) · Adam J Hanje, MD (1) · Alexander R Schmidt, MD (1) · Alexandre Ghuysen, MD, PhD (1) · Annabel Blasi, MD, PhD (1) · Anne Godier, MD-PhD (1) · Arya Mani, MD (1) · Barto Nascimento, MD MSc (1) · Bellal Joseph, MD (1) · Benjamin Bourdois, MD (1) · Bryan Cotton, MD (1) · Burhan Dost, Assoc. Prof. (1) · Christian F Weber, Dr. (1) · Christine Gaarder, MD (1)
PMID 15028145, PMID 16010055, PMID 16174954, PMID 16545046, PMID 18212647, PMID 18564410, PMID 21130474, PMID 21772125, PMID 21982521, PMID 22274142, PMID 22307074, PMID 23215886, PMID 23590915, PMID 24040574, PMID 25244877, PMID 26745506, PMID 28228155, PMID 28549445, PMID 29047413, PMID 29274254, PMID 30318393, PMID 31104069, PMID 31405567, PMID 31846350, PMID 32697484, PMID 32894734, PMID 32894735, PMID 33042916, PMID 33293819, PMID 34215251, PMID 34225348, PMID 34479938, PMID 34519356, PMID 34643817, PMID 35244208, PMID 35508351, PMID 36163263, PMID 36376099, PMID 36855941, PMID 36945200, PMID 37380568, PMID 37489818, PMID 37697231, PMID 38282333, PMID 38710463, PMID 40095320, PMID 40271704, PMID 40420619, PMID 40982282, PMID 42030009
2019 (1), K23HL147799 (1), SC2HL110393 (1)