5 completed, 2 unknown. 7 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 5, Unknown 2 |
| Phase 2 | 1 | Unknown 1 |
Follow Coagulopathy: new trials by email Literature Review of Coagulopathy trials Research Report on Coagulopathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fibrinogen Early In Severe Trauma StudY II Fibrinogen Concentrate, Cryoprecipitate - Trauma, Haemorrhagic Shock | Phase 3 | Completed | Australian and New Zealand Intensive Care Research Centre | 900 | 2022-11-21 | 2026-09-09 |
| Evaluation of a Transfusion Therapy Using Whole Blood in the Management of Coagulopathy in Patients With Acute Traumatic Hemorrhage Whole blood transfusion, Fractionated blood products transfusion - Trauma, Acute Hemorrhage | Phase 3 | Completed | Direction Centrale du Service de Santé des Armées | 200 | 2021-12-04 | 2026-01-26 |
| Steroids and Unfractionated Heparin in Critically Ill Patients With Pneumonia From COVID-19 Infection Enoxaparin, Methylprednisolone, unfractionated heparin - Covid19, SARS-CoV Infection | Phase 3 | Unknown | Massimo Girardis | 210 | 2020-11-25 | 2021-05-06 |
| Safety and Efficacy Study Comparing Pad-gauze With Anti-fibrinolytic Agent Hemostopan™) to a Regular Pad-gauze pad-gauze with tranexamic acid (Hemostopan™) - Bleeding, Coagulopathy | Phase 2 / Phase 3 | Unknown | Sion Microtec Ltd. | 25 | 2013-10-01 | 2015-02-13 |
| Freeze-dried Plasma in the Initial Management of Coagulopathy in Trauma Patients Freezed-dried plasma, Fresh-frozen plasma - Trauma, Coagulopathy | Phase 3 | Completed | University Hospital, Lille | 42 | 2013-07-09 | 2026-04-22 |
| Phase 3 Safety and Efficacy Study of ART-123 in Subjects With Severe Sepsis and Coagulopathy ART-123, Placebo - Severe Sepsis, Coagulopathy | Phase 3 | Completed | Asahi Kasei Pharma America Corporation | 816 | 2012-10-29 | 2020-04-21 |
| Trial to See if Topical Pennsaid for Knee Pain Affects Coagulation Values in Patients Who Are Also Taking Anticoagulants Pennsaid - Osteoarthritis of the Knee, Coagulopathy | Phase 3 | Completed | Nathan Wei, MD, FACP, FACR: | 22 | 2012-02-01 | 2014-06-26 |
Hemostatic Disorders (7) · Wounds and Injuries (3) · COVID-19 (1) · Critical Illness (1) · Hemorrhage (1) · Osteoarthritis (1) · Osteoarthritis, Knee (1) · Pneumonia, Viral (1) · Sepsis (1) · Severe Acute Respiratory Syndrome (1) · Shock, Hemorrhagic (1)
Cardiovascular Diseases (7) · Hematologic Diseases (7) · Hemic and Lymphatic Diseases (7) · Hemorrhagic Disorders (7) · Vascular Diseases (7) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Infections (2) · Arthritis (1) · Coronaviridae Infections (1) · Coronavirus Infections (1) · Disease Attributes (1) · Hemorrhage (1) · Inflammation (1) · Joint Diseases (1)
ART123 (1) · Anti-Inflammatory Agents, Non-Steroidal (1) · Diclofenac (1) · Enoxaparin (1) · Exchange Transfusion, Whole Blood (1) · Fibrinogen (1) · Heparin (1) · Methylprednisolone (1) · Methylprednisolone Hemisuccinate (1) · Solutions (1) · cryoprecipitate coagulum (1)
Asahi Kasei Pharma America Corporation (1) · Australian and New Zealand Intensive Care Research Centre (1) · Direction Centrale du Service de Santé des Armées (1) · Massimo Girardis (1) · Nathan Wei, MD, FACP, FACR: (1) · Sion Microtec Ltd. (1) · University Hospital, Lille (1)
France (3) · Australia (2) · Israel (2) · New Zealand (2) · United States (2) · Argentina (1) · Belgium (1) · Brazil (1) · Bulgaria (1) · Canada (1) · Croatia (1) · Czechia (1) · Finland (1) · Germany (1) · Hungary (1)
David Fineberg, M.D. (1) · Massimo Girardis, PI (1) · Mudi Misgav, MD (1) · Nathan Wei, MD,FACP,FACR (1) · Sophie Susen, MD,PhD (1) · Zoe McQuilten, MBBS (1)
PMID 29274254, PMID 31104069, PMID 32697484, PMID 35244208, PMID 40271704, PMID 40420619