4 not yet recruiting, 2 completed, 2 recruiting. 6 Not applicable, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Not yet recruiting 3, Recruiting 2, Completed 1 |
| Phase 3 | 1 | Not yet recruiting 1 |
| Phase 4 | 1 | Completed 1 |
Follow Cleft Lip Palate: new trials by email Literature Review of Cleft Lip Palate trials Research Report on Cleft Lip Palate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Quadratus Lumborum Block for Iliac Bone Harvest in Pediatric Cleft Alveolus Repair Lateral quadratus lumborum block, Sham Block - Cleft Lip Palate | Not applicable | Not yet recruiting | Oslo University Hospital | 50 | 2026-09-01 | 2026-09-29 |
| Safety and Efficacy of Bone Bioengineering Kit With Stem Cells for Alveolar Cleft Repair Bioengineering kit composed of stem cells from deciduous teeth and biomaterial., iliac crest bone graft surgery - Cleft Lip Palate | Phase 3 | Not yet recruiting | Instituto de Tecnologia do Paraná | 205 | 2026-07-01 | 2026-07-10 |
| Early Intervention in Infants With Unrepaired Cleft Palate: Language, Palatal Function, and Articulation. Early intervention for language, articulation and palatal function skills - Cleft Lip and Cleft Palate, Cleft Lip Palate | Not applicable | Not yet recruiting | Old Dominion University | 200 | 2025-10-21 | 2025-10-22 |
| Time and Type Dependent Evaluation of Different Techniques for Correction of Cleft Maxillary Hypoplasia orthognathic surgery ,lefort 1,bsso ,DO, distraction osteogenesis - Maxillary Hypoplasia, Cleft Lip Palate | Not applicable | Not yet recruiting | Assiut University | 22 | 2025-02-21 | 2025-02-28 |
| Effect of Opioid-Free vs Opioid-Based Anesthesia on Postoperative Pain and Emergence Agitation in Children Undergoing Cleft Surgery Ketamine (1 mg/kg), Dexmedetomidine (1-0,8-0,6-0,4 mcg/kg/h), Fentanyl 5 mcg/kg - Cleft Lip Palate, Orofacial Cleft | Not applicable | Recruiting | Iva Smiljanić | 90 | 2024-05-16 | 2026-04-29 |
| Clinical Application of Artificial Intelligence in New Borns With Cleft Lip and Palate AI-Designed Passive Plate Therapy - Congenital Disorder, Cleft Lip Palate | Not applicable | Recruiting | University Hospital, Basel, Switzerland | 70 | 2023-08-01 | 2025-05-16 |
| Evaluation of Modified Le Fort I Osteotomy for Treating Cleft Lip and Palate Patients segmental Le Fort I (SLF-1) osteotomy - Cleft Lip Palate, Class III Skeletal Malocclusion | Phase 4 | Completed | Alexandria University | 9 | 2020-01-01 | 2026-02-20 |
| Nasoalveolar Molding for Egyptian Cleft Lip Palate Infants Nasoalveolar molding therapy - Cleft Lip Palate, Cleft Lip, Unilateral, Complete | Not applicable | Completed | Alexandria University | 60 | 2016-03-01 | 2022-05-03 |
Cleft Lip (2) · Agnosia (1) · Cleft Palate (1) · Communication (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Emergence Delirium (1) · Language (1) · Pain, Postoperative (1) · Retrognathia (1) · Speech (1)
Congenital Abnormalities (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Stomatognathic Diseases (3) · Stomatognathic System Abnormalities (3) · Craniofacial Abnormalities (2) · Jaw Abnormalities (2) · Jaw Diseases (2) · Lip Diseases (2) · Maxillofacial Abnormalities (2) · Mouth Abnormalities (2) · Mouth Diseases (2) · Musculoskeletal Abnormalities (2) · Musculoskeletal Diseases (2) · Neurologic Manifestations (2) · Pathologic Processes (2)
Biocompatible Materials (1) · Dexmedetomidine (1) · Early Intervention, Educational (1) · Fentanyl (1) · Ketamine (1) · Nasoalveolar Molding (1) · Nitrous Oxide (1) · Osteogenesis, Distraction (1) · Osteotomy (1) · Oxygen (1) · Propofol (1) · Sevoflurane (1) · Vecuronium Bromide (1)
Alexandria University (2) · Assiut University (1) · Instituto de Tecnologia do Paraná (1) · Iva Smiljanić (1) · Old Dominion University (1) · Oslo University Hospital (1) · University Hospital, Basel, Switzerland (1)
Egypt (2) · Brazil (1) · Croatia (1) · India (1) · Norway (1) · United States (1)
Andreas Mueller, PhD,MHBA (1) · Iva Smiljanic, MD, MSc (1) · Mona S. Saad, MSc (1) · Prasad Nalabothu, MDS PhD (1) · Victoria Reynolds, LLB BSc PhD (1)
PMID 31860800, PMID 32244361, PMID 36010151, PMID 36154982, PMID 37009952, PMID 37184464