9 recruiting, 7 not yet recruiting, 5 completed, 1 active not recruiting. 14 Not applicable, 4 Phase 2, 3 Phase 3, 1 Phase 1.
Follow Chemotherapy Induced Peripheral Neuropathy (CIPN): new trials by email Literature Review of Chemotherapy Induced Peripheral Neuropathy (CIPN) trials Research Report on Chemotherapy Induced Peripheral Neuropathy (CIPN)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Stibium Metallicum Praeparatum D6 Versus Placebo in the Reduction of Paclitaxel-induced Peripheral Neurotoxicity Stibium metallicum praeparatum 6x, Placebo - Chemotherapy Induced Peripheral Neuropathy (CIPN) | Phase 3 | Not yet recruiting | University of Bern | 86 | 2027-01-01 | 2026-09-15 |
| Intrathecal Ziconotide in Chemotherapy Induced Peripheral Neuropathy Ziconotide - Chemotherapy Induced Peripheral Neuropathy (CIPN) | Not yet recruiting | Christian Hospital Northeast Northwest | 24 | 2026-05-02 | 2026-03-30 | |
| Whole-Body Vibration on Balance, Risk of Falling and Quality of Life in Chemotherapy-Induced Peripheral Neuropathy Whole Body Vibration, Traditional exercise - Whole Body Vibration, Chemotherapy Induced Peripheral Neuropathy (CIPN) | Not applicable | Not yet recruiting | Cairo University | 30 | 2026-04-01 | 2026-04-02 |
| Assessing Functional Impairments in Patients With Chemotherapy-Induced Peripheral Neuropathy Questionnaire and Physical Exam - Chemotherapy Induced Peripheral Neuropathy (CIPN) | Recruiting | Paracelsus Medical University | 120 | 2026-03-15 | 2026-08-19 | |
| SPENDD: Quantitative Sensory Testing and Analgesic Response for Painful Peripheral Neuropathy. Pregabalin, Duloxetine, Placebo - Painful Peripheral Neuropathy, Diabetic Peripheral Neuropathic Pain (DPN) | Phase 2 | Recruiting | University of Rochester | 190 | 2026-02-02 | 2026-09-16 |
| Preliminary Effectiveness and Feasibility of Transcutaneous Acupoints Electrical Stimulation on Chemotherapy-induced Peripheral Neuropathy Among Children With Acute Lymphoblastic Leukemia Transcutaneous Acupoints Electrical Stimulation (TAES), No intervention: sham TAES - Chemotherapy Induced Peripheral Neuropathy (CIPN) | Not applicable | Not yet recruiting | The Hong Kong Polytechnic University | 60 | 2026-02-01 | 2026-01-06 |
| Effect of Feedback-Based Balance Training on Balance and Gait in Cancer Patients With Chemotherapy-Induced Peripheral Neuropathy Feedback-Based Balance and Gait Training, Conventional Physiotherapy - Chemotherapy Induced Peripheral Neuropathy (CIPN) | Not applicable | Completed | King Edward Medical University | 70 | 2026-01-29 | 2026-10-08 |
| Feasibility Testing of a Tai Chi Program for Chemotherapy-Induced Peripheral Neuropathy Treatment (TCT) Tai Chi Program - Chemotherapy Induced Peripheral Neuropathy (CIPN), Peripheral Neuropathy Due to Chemotherapy | Not applicable | Active not recruiting | Dana-Farber Cancer Institute | 21 | 2026-01-16 | 2026-09-22 |
| Exploring the Effects of Magnesium Ions on Peripheral Neuropathy, Serum Magnesium Ion Concentration,Sleep Quality, and Quality of Life in Patients With Colorectal Cancer Receiving Chemotherapy. oral magnesium ions, oral magnesium ions and warm water with Gu Bao Sapindus mukorossi magnesium ion solution - Colorectal Cancer (CRC), Chemotherapy Induced Peripheral Neuropathy (CIPN) | Not applicable | Not yet recruiting | Kaohsiung Medical University Chung-Ho Memorial Hospital | 75 | 2026-01-01 | 2026-01-16 |
| Improving Chemotherapy Induced Peripheral Neuropathy in Children With Leukemia: A Study of Transcutaneous Acupoints Electrical Stimulation and Auricular Acupressure Interventions Transcutaneous Acupoints Electrical Stimulation (TAES), Auricular Acupressure (AA), No intervention - Chemotherapy Induced Peripheral Neuropathy (CIPN) | Not applicable | Not yet recruiting | The Hong Kong Polytechnic University | 132 | 2025-12-08 | 2025-12-12 |
| Evaluation of Effectiveness of Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy for Treatment of Chemotherapy Induced Peripheral Neuropathy Chemotherapy Induced Peripheral Neuropathy (CIPN), Neuropathic Pain | Recruiting | Rijnstate Hospital | 20 | 2025-12-01 | 2025-12-26 | |
| Multimodal Assessment of Cryotherapy for Paclitaxel-Induced Neuropathy Cryotherapy - CIPN - Chemotherapy-Induced Peripheral Neuropathy, CIPN | Not applicable | Recruiting | Azienda Sanitaria dell'Alto Adige | 144 | 2025-10-11 | 2026-08-24 |
| The Lilac Device Trial - IMPACT: A Clinical Investigation on IMproving Peripheral Neuropathy Induced by Chemotherapy With Advanced Compression Technology - A Safety and Efficacy Study The Lilac Device, Sham device - Chemotherapy Induced Peripheral Neuropathy (CIPN) | Not applicable | Recruiting | Luminate Medical, Inc. | 142 | 2025-10-03 | 2026-06-10 |
| Simple Surgical Glove Compression to Prevent Chemotherapy-Induced Peripheral Neuropathy Simple Surgical Glove Compression Technique - Breast Cancer, Chemotherapy Induced Peripheral Neuropathy (CIPN) | Not applicable | Not yet recruiting | Jinsong Lu | 44 | 2025-09-15 | 2025-09-12 |
| Helping Cancer Patients Manage Neuropathy Symptoms From Chemotherapy With a Low-Intensity, Low-Risk Cranial PEMF Device SHIFT - Chemotherapy Induced Peripheral Neuropathy, Chemotherapy Induced Peripheral Neuropathy (CIPN) | Not applicable | Enrolling by invitation | FluxWear, INC | 50 | 2025-06-23 | 2025-07-11 |
| The Effect of Personalized Exercise Interventions for the Prevention of Chemotherapy-induced Peripheral Neuropathy Exercise intervention - Chemotherapy Induced Peripheral Neuropathy (CIPN) | Not applicable | Recruiting | Universiteit Antwerpen | 206 | 2025-06-05 | 2025-07-09 |
| The Effect of Cold Salt Water Foot Bath on the Development Of Chemotherapy-Induced Peripheral Neuropathy Cold salt water foot bath, Cold water foot bath - Breast Cancer Patients, Chemotherapy Induced Peripheral Neuropathy (CIPN) | Not applicable | Recruiting | Tuba Eryiğit | 30 | 2025-06-01 | 2026-04-16 |
| Effect of GMI With and Without NM on LE in Cancer Patients With CIPN Graded Motor Imagery, Neural Mobilization - Chemotherapy Induced Peripheral Neuropathy (CIPN), Cancer | Not applicable | Completed | University of Faisalabad | 48 | 2025-03-01 | 2026-07-17 |
| Ozone Treatment in Paresthesia (Numbness, Tingling) Secondary to Chemotherapy-induced Peripheral Neuropathy Ozone therapy, Oxygen (placebo) - Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia | Phase 2 / Phase 3 | Recruiting | Bernardino Clavo, MD, PhD | 42 | 2025-02-07 | 2026-09-18 |
| Gut Microbiome Profiles in Patients With Chemotherapy-induced Neuropathy in the RCT OzoParQT (NCT06706544). Ozone therapy, Oxygen (placebo) - Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia | Phase 2 / Phase 3 | Recruiting | Bernardino Clavo, MD, PhD | 42 | 2025-02-07 | 2026-09-25 |
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Breast Neoplasms (3) · Peripheral Nervous System Diseases (3) · Anxiety Disorders (2) · Depression (2) · Hypesthesia (2) · Neuralgia (2) · Paresthesia (2) · Ataxia (1) · Chronic Pain (1) · Colonic Neoplasms (1) · Colorectal Neoplasms (1) · Leukemia (1) · Motor Activity (1) · Neoplasms (1) · Neurotoxicity Syndromes (1)
Nervous System Diseases (8) · Neoplasms (7) · Neoplasms by Site (5) · Neurologic Manifestations (5) · Neuromuscular Diseases (5) · Pathological Conditions, Signs and Symptoms (5) · Signs and Symptoms (5) · Behavior (3) · Breast Diseases (3) · Mental Disorders (3) · Pain (3) · Skin Diseases (3) · Skin and Connective Tissue Diseases (3) · Behavioral Symptoms (2) · Colonic Diseases (2)
Oxygen (2) · Cryotherapy (1) · Duloxetine Hydrochloride (1) · N,N'-bis(pyridoxal-5-phosphate)ethylenediamine-N,N'-diacetic acid (1) · Physical Examination (1) · Pregabalin (1) · Tadalafil (1) · ziconotide (1)
Bernardino Clavo, MD, PhD (2) · The Hong Kong Polytechnic University (2) · Azienda Sanitaria dell'Alto Adige (1) · Cairo University (1) · Christian Hospital Northeast Northwest (1) · Dana-Farber Cancer Institute (1) · Egetis Therapeutics AB (publ) (1) · FluxWear, INC (1) · Jinsong Lu (1) · Kaohsiung Medical University Chung-Ho Memorial Hospital (1) · King Edward Medical University (1) · Luminate Medical, Inc. (1) · P. Herzen Moscow Oncology Research Institute (1) · Paracelsus Medical University (1) · Rijnstate Hospital (1)
United States (6) · China (3) · Pakistan (2) · Spain (2) · Taiwan (2) · Austria (1) · Belgium (1) · Ireland (1) · Italy (1) · Netherlands (1) · Russia (1) · Sweden (1) · Turkey (Türkiye) (1)
Bernardino Clavo, MD, PhD (2) · Amna Zia, PhD. Scholar (1) · Anton Oseledchyk, PD Dr. med. (1) · Bothina Sayed Mohamed, Bachelor's Degree (1) · Christopher L Beuer, MD (1) · Himar Fabelo, BSc, PhD (1) · Inger Andreasson, MD (1) · Jacob Lorenzo-Morales, Prof (1) · Jennifer Gewandter, PhD, MPH (1) · Mohamed Abd El-Rahman Hassan, Professor of Clinical Oncology (1) · Mohamed Helayel Marzouk, Lecture of Physical Therapy (1) · Muhammad Saad Khalid (1) · Nahed Ahmed Salem, Professor of Physical Therapy (1)