10 completed, 5 unknown, 2 not yet recruiting, 1 enrolling by invitation. 5 Not applicable, 3 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 2, Not yet recruiting 1, Recruiting 1, Unknown 1 |
| Phase 3 | 3 | Completed 3 |
| Phase 4 | 1 | Completed 1 |
Follow Cervical Spondylotic Myelopathy: new trials by email Literature Review of Cervical Spondylotic Myelopathy trials Research Report on Cervical Spondylotic Myelopathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Biomarkers of Cervical Spondylotic Myelopathy Cervical Spondylotic Myelopathy | Not yet recruiting | University of California, San Francisco | 50 | 2026-09-01 | 2026-08-20 | |
| Efficacy of Two Approaches in Cervical Single-door Laminoplasty for Spinal Canal Enlargement Expansive open-door laminoplasty via intermuscular space approach, cervical single-door laminoplasty via the conventional approach - Cervical Spondylotic Myelopathy | Not applicable | Not yet recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 376 | 2025-04-15 | 2025-04-24 |
| Screening and Prospective Cohort Study of Risk Factors for Enhanced Recovery After Spinal Fusion Surgery in Advanced Age Patient This is an observational study - Lumbar Disk Herniation, Lumbar Spinal Stenosis | Enrolling by invitation | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 500 | 2024-09-03 | 2024-09-19 | |
| Efficacy and Safety of Shenqi Sherong Pill in Participants With Cervical Spondylotic Myelopathy Shenqi Sherong Pill, Placebo - Cervical Spondylotic Myelopathy | Phase 3 | Completed | Shanghai Hutchison Pharmaceuticals Limited | 428 | 2024-05-11 | 2026-09-11 |
| Fusion or no Fusion After Decompression of the Spinal Cord in Patients With Degenerative Cervical Myelopathy Muscle preserving selective laminectomy, Laminectomy with instrumented fusion - Cervical Spondylotic Myelopathy | Not applicable | Recruiting | Uppsala University Hospital | 300 | 2022-02-21 | 2025-04-08 |
| Comparison of IONM Between Remimazolam and Propofol Arm I (Propofol), Arm II (Remimazolam) - Ossification Posterior Longitudinal Ligament, Cervical Spondylotic Myelopathy | Not applicable | Completed | Gangnam Severance Hospital | 66 | 2021-07-20 | 2023-10-18 |
| Diffusion MRI in Cervical Spondylotic Myelopathy diffusion MRI (dMRI) - Cervical Spondylotic Myelopathy | Unknown | Peking University Third Hospital | 200 | 2020-09-01 | 2021-07-07 | |
| The Application of Enhanced Recovery After Surgery Clinical Pathway in Posterior Cervical Spine Surgery Cervical Spondylotic Myelopathy, Ossification of Posterior Longitudinal Ligament in Cervical Region | Unknown | Peking University Third Hospital | 400 | 2020-08-01 | 2021-12-08 | |
| Postural Stability in Cervical Spinal Myelopathy Cervical Spondylotic Myelopathy | Completed | VA Office of Research and Development | 8 | 2019-02-07 | 2025-12-15 | |
| Gait in Adult Patients With Cervical Spondylotic Myelopathy Surgical intervention - Cervical Spondylotic Myelopathy | Not applicable | Unknown | Texas Back Institute | 100 | 2018-03-22 | 2018-05-01 |
| Diffusion MRI in Cervical Spondylotic Myelopathy (CSM) MRI with DBSI technology - Cervical Spondylotic Myelopathy | Completed | Washington University School of Medicine | 71 | 2018-01-29 | 2026-03-17 | |
| Effect of Topical Corticosteroids on Dysphagia in Anterior Cervical Discectomy and Fusion Methylprednisolone Acetate, Hemostatic Matrix Kit - Cervical Disc Herniation, Cervical Degenerative Disc Disease | Not applicable | Completed | Hospital for Special Surgery, New York | 128 | 2015-08-01 | 2023-07-10 |
| Efficacy of Riluzole in Surgical Treatment for Cervical Spondylotic Myelopathy (CSM-Protect) riluzole, Placebo medication - Cervical Spondylotic Myelopathy | Phase 3 | Completed | AOSpine North America Research Network | 270 | 2012-03-01 | 2018-11-02 |
| Effectiveness of T2* MRI in Cervical Spondylotic Myelopathy MRI - Cervical Spondylotic Myelopathy | Unknown | Peking University Third Hospital | 200 | 2010-01-01 | 2021-07-08 | |
| Pregabalin and Radicular Pain Study (PARPS) Pregabalin - Cervical Spondylosis, Cervical Spondylotic Myelopathy | Phase 4 | Completed | Singapore General Hospital | 50 | 2008-01-01 | 2011-07-06 |
| Surgical Treatment of Cervical Spondylotic Myelopathy Cervical Spondylotic Myelopathy | Completed | AO Clinical Investigation and Publishing Documentation | 479 | 2007-11-01 | 2015-03-06 | |
| The CSM Trial: A Multicenter Study Comparing Ventral to Dorsal Surgery for Cervical Spondylotic Myelopathy Ventral Surgical Decompression with Instrumented Fusion, Dorsal Decompression With or Without Fusion - Cervical Spondylotic Myelopathy | Phase 3 | Completed | Greenwich Hospital | 103 | 2006-11-01 | 2012-08-29 |
| Assessment of Surgical Techniques for Treating Cervical Spondylotic Myelopathy Laminectomy and Laminoplasty - Cervical Spondylotic Myelopathy | Completed | AOSpine North America Research Network | 321 | 2005-12-01 | 2017-11-01 | |
| Anterior Vs Posterior Procedures for Cervical Spondylotic Myelopathy: Prospective Randomized Clinical Trial ACDF, Cervical laminoplasty - Cervical Spondylotic Myelopathy | Unknown | The University of Hong Kong | 100 | 2001-05-01 | 2010-01-14 |
Spondylosis (3) · Spinal Cord Diseases (2) · Spinal Cord Injuries (2) · Deglutition Disorders (1) · Intervertebral Disc Displacement (1) · Klippel-Feil Syndrome (1) · Ossification of Posterior Longitudinal Ligament (1) · Radiculopathy (1) · Spinal Cord Compression (1) · Spinal Stenosis (1) · Spondylolisthesis (1)
Bone Diseases (6) · Musculoskeletal Diseases (6) · Spinal Diseases (5) · Nervous System Diseases (4) · Central Nervous System Diseases (3) · Pathological Conditions, Signs and Symptoms (2) · Trauma, Nervous System (2) · Wounds and Injuries (2) · Bone Diseases, Developmental (1) · Congenital Abnormalities (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Digestive System Diseases (1) · Dysostoses (1) · Esophageal Diseases (1) · Gastrointestinal Diseases (1)
Laminectomy (2) · Diffusion Tensor Imaging (1) · Gene Fusion (1) · Laminoplasty (1) · Magnetic Resonance Imaging (1) · Methylprednisolone Acetate (1) · Pregabalin (1) · Propofol (1) · Riluzole (1) · Surgical Procedures, Operative (1) · remimazolam (1)
Peking University Third Hospital (3) · AOSpine North America Research Network (2) · AO Clinical Investigation and Publishing Documentation (1) · Gangnam Severance Hospital (1) · Greenwich Hospital (1) · Hospital for Special Surgery, New York (1) · Shanghai Hutchison Pharmaceuticals Limited (1) · Singapore General Hospital (1) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (1) · Texas Back Institute (1) · The University of Hong Kong (1) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (1) · University of California, San Francisco (1) · Uppsala University Hospital (1) · VA Office of Research and Development (1)
United States (7) · China (5) · Canada (3) · Singapore (1) · South Korea (1) · Sweden (1)
Michael Fehlings, MD, PhD (2) · Anna MacDowall, MD, PhD (1) · Bolai Chen, doctor (1) · Branko Kopjar, MD (1) · Edward C. Benzel, MD (1) · Huishu Yuan (1) · Huishu Yuan, Dr (1) · Jean-Valery Coumans, MD (1) · Keith DK Luk, MBBS, FRCS (1) · Kenneth MC Cheung, MBBS, FRCS (1) · Michael Fehlings, MD (1) · Nima Alan, MD (1) · Richard J. Servatius, PhD (1) · Robert Heary, MD (1) · Ronald Apfelbaum (1)
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