28 completed, 16 unknown, 10 recruiting, 6 withdrawn. 17 Not applicable, 8 Phase 2, 6 Phase 1, 5 Phase 3, 4 Phase 4.
Follow Carotid Atherosclerosis: new trials by email Literature Review of Carotid Atherosclerosis trials Research Report on Carotid Atherosclerosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Photon-Counting CT Versus Conventional CT for Carotid Plaque Assessment in Patients With Carotid Artery Stenosis Carotid Artery Stenosis, Carotid Atherosclerosis | Recruiting | Chinese PLA General Hospital | 100 | 2026-01-07 | 2026-08-20 | |
| Microflow3D - Non-invasive Mapping of Coronary Arteries and the Cerebral Vascular Network Using 3D Ultrasound Localization Microscopy in Patients With Atherosclerosis Prior to Carotid Endarterectomy Surgery Ultrasound localization microscopy, circle of Willis, Ultrasound localization microscopy, coronary arteries - Carotid Atherosclerosis | Not applicable | Not yet recruiting | French Cardiology Society | 37 | 2025-11-01 | 2025-09-25 |
| 3D Contrast Enhanced Microvascular Ultrasound of Carotid Atherosclerosis for the Detection of Carotid Plaque Neo-Revascularisation. 3D Contrast Enhanced Microvascular Carotid Ultrasound - Carotid Atherosclerosis, Ultrasound | Not applicable | Recruiting | London North West Healthcare NHS Trust | 10 | 2025-10-16 | 2026-04-13 |
| SIALIDASE INHIBITION AS ANTIATHEROSCLEROTIC THERAPY Placebo, Tertinat - Atherosclerosis, Atheroscleroses, Coronary | Phase 2 | Active not recruiting | Institute for Atherosclerosis Research, Russia | 1228 | 2024-08-29 | 2026-07-20 |
| The Role of Maintaining External Carotid Artery Flow in Graft Interposition After Carotid Endarterectomy Carotid graft interposition - Carotid Artery Diseases, Stroke | Unknown | Institute for Cardiovascular Diseases Dedinje | 250 | 2024-06-12 | 2024-07-30 | |
| Carotid Plaque RADS vs CPVH: Diagnostic Accuracy Comparison Carotid Ultrasound with CPVH and Carotid Plaque RADS Assessment - Carotid Artery Stenosis Asymptomatic, Carotid Atherosclerosis | Completed | Limited Liability Company "European Institute of Family Health" | 150 | 2024-05-20 | 2026-10-13 | |
| Immunomodulatory Effects of PCSK9 Inhibition 99mTc-tilmanocept SPECT/CT scanning - Atherosclerotic Cardiovascular Disease, Cardiovascular Diseases | Withdrawn | Massachusetts General Hospital | 2024-04-04 | 2025-09-26 | ||
| Coated or Chewable Aspirin and a Hybrid Strategy to Mitigate Adverse Effects of Air Pollution in Stable Atherosclerotic Disease Enteric-coated aspirin, Plain aspirin, Hybrid strategy - Atherosclerotic Cardiovascular Disease, Coronary Artery Disease | Not applicable | Recruiting | Rajaie Cardiovascular Medical and Research Center | 3000 | 2024-03-06 | 2025-03-19 |
| Carotid Atherosclerosis in Predicting Coronary Artery Disease coronary agiongraphy - Carotid Atherosclerosis, Coronary Atheroscleroses | Recruiting | Shanghai Zhongshan Hospital | 1000 | 2024-02-10 | 2024-02-12 | |
| Comparison Between Different Techniques for Carotid Artery Endarterectomy carotid endarterectomy - Carotid Stenosis, Carotid Atherosclerosis | Not applicable | Unknown | Sohag University | 40 | 2024-02-01 | 2024-01-17 |
| Study on Hyperlipidemia Combined With Carotid Atherosclerosis With ShenJu Granules ShenJu, Placebo - Hyperlipidemia, Carotid Atherosclerosis | Not applicable | Unknown | Guangdong Provincial Hospital of Traditional Chinese Medicine | 80 | 2023-09-20 | 2023-12-12 |
| Sonodynamic Therapy Manipulates Atherosclerosis Regression Trial on Patients With Carotid Atherosclerotic Plaques Sonodynamic therapy (SDT), pseudo-SDT - Carotid Atherosclerosis | Phase 1 / Phase 2 | Withdrawn | First Affiliated Hospital of Harbin Medical University | 2023-09-20 | 2023-09-21 | |
| The Effect of Low-dose Interleukin-2 on the Immune Landscape of Human Atherosclerotic Plaques at Single Cell Resolution. Interleukin-2 [IL-2], Standard care - Carotid Endarterectomy - TIA, Carotid Artery Plaque | Not applicable | Active not recruiting | Cambridge University Hospitals NHS Foundation Trust | 30 | 2023-08-26 | 2025-05-30 |
| Prediction of Cerebral Hyperperfusion Syndrome After Carotid Revascularization Using Deep Learning Carotid revascularization - Carotid Artery Diseases, Carotid Atherosclerosis | Recruiting | State Institution "Republican Scientific and Practical Center" Cardiology, Belarus | 500 | 2023-05-03 | 2025-11-25 | |
| CANF-Comb-II PET-MR in Atherosclerosis Multisite 64Cu-25%-CANF-Comb - Carotid Atherosclerosis, Asymptomatic Carotid Artery Stenosis | Recruiting | Washington University School of Medicine | 80 | 2023-03-21 | 2026-03-23 | |
| Shear Wave Elastography for Carotid Atherosclerotic Plaques Vascular Ultrasound, Shear Wave Elastography, Greyscale Median - Carotid Atherosclerosis | Recruiting | UPECLIN HC FM Botucatu Unesp | 43 | 2023-03-01 | 2025-04-06 | |
| Carotid Artery Stenting During Endovascular Treatment of Acute Stroke carotid artery stenting during EVT, no carotid artery stenting during EVT - Stroke, Acute, Stroke, Ischemic | Phase 3 | Recruiting | University Medical Center Groningen | 600 | 2022-11-15 | 2024-07-19 |
| Ophthalmologic Outcomes in Patients With Carotid Artery Stenosis eye - Optcial coherence tomography - Choroid Disease, Carotid Stenosis | Unknown | Universidade do Porto | 40 | 2022-01-01 | 2022-11-21 | |
| Ultrafast Ultrasound Imaging Assesment of Carotid Plaque Neovascularization contrast enhanced ultrafast ultrasound imaging - Carotid Stenosis, Carotid Artery Diseases | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 40 | 2021-03-17 | 2024-07-11 |
| Risk Assessment of Carotid Plaques Using 3D Contrast-Enhanced Ultrasound Perflutren - Carotid Atherosclerosis | Phase 4 | Unknown | Thomas Jefferson University | 20 | 2020-12-01 | 2025-04-24 |
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Carotid Artery Diseases (67) · Carotid Stenosis (18) · Stroke (13) · Atherosclerosis (12) · Plaque, Atherosclerotic (6) · Aortic Aneurysm, Abdominal (4) · Cardiovascular Diseases (4) · Diabetes Mellitus (4) · Ischemic Stroke (4) · Vascular Diseases (4) · Coronary Artery Disease (3) · Diabetes Mellitus, Type 2 (3) · Hyperlipidemias (3) · Hypertension (3) · Inflammation (3)
Brain Diseases (67) · Central Nervous System Diseases (67) · Cerebrovascular Disorders (67) · Nervous System Diseases (67) · Cardiovascular Diseases (63) · Vascular Diseases (63) · Arterial Occlusive Diseases (31) · Arteriosclerosis (15) · Pathological Conditions, Signs and Symptoms (15) · Metabolic Diseases (10) · Nutritional and Metabolic Diseases (10) · Pathologic Processes (8) · Pathological Conditions, Anatomical (8) · Endocrine System Diseases (7) · Glucose Metabolism Disorders (7)
Atorvastatin (2) · Blood Specimen Collection (2) · Endarterectomy, Carotid (2) · Magnetic Resonance Imaging (2) · Ultrasonography, Carotid Arteries (2) · Aspirin (1) · Cholesterol (1) · Cilostazol (1) · CuATSM (1) · Cytokines (1) · FPP(RGD)2 (1) · Injections (1) · Interleukin-2 (1) · Metformin (1) · Niacin (1)
Assistance Publique - Hôpitaux de Paris (3) · Institute for Atherosclerosis Research, Russia (3) · Washington University School of Medicine (3) · Elucid Bioimaging Inc. (2) · First Affiliated Hospital of Harbin Medical University (2) · Hospices Civils de Lyon (2) · Mid Western Regional Hospital, Ireland (2) · Silk Road Medical (2) · Abbott Medical Devices (1) · Aristotle University Of Thessaloniki (1) · Azienda Ospedaliero, Universitaria Pisana (1) · Azienda Ospedaliero-Universitaria di Modena (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Central Jutland Regional Hospital (1) · Centre Hospitalier Universitaire de Besancon (1)
United States (14) · China (9) · France (8) · Russia (5) · Italy (3) · Spain (3) · United Kingdom (3) · Denmark (2) · Ireland (2) · South Korea (2) · Belarus (1) · Belgium (1) · Brazil (1) · Czechia (1) · Egypt (1)
Alexander N. Orekhov, Prof., PhD, DSci (1) · Andrew J. Buckler, M.S. (1) · Anne-Laure Calderon, MD (1) · Barbara V Howard, PhD (1) · Bernard Allaouchiche, MD PhD (1) · Brajesh K. Lal, MD (1) · Christos Liapis, Professor (1) · Cyrille Truc, MD (1) · Ebo de Muinck, Professor (1) · Emilie N Eilersen, MD (1) · Emilio Ortega, MD; PhD (1) · Emmanuel Boselli, MD PhD (1) · Farida Benatir, MD (1)
PMID 10942686, PMID 15705900, PMID 15950949, PMID 1749920, PMID 17993611, PMID 18398080, PMID 19095139, PMID 20142180, PMID 20222019, PMID 20958974, PMID 21307169, PMID 21788602, PMID 22454248, PMID 24464597, PMID 24768795, PMID 24956535, PMID 25022935, PMID 25142320, PMID 25264981, PMID 25453890, PMID 25903752, PMID 28858564, PMID 31934592, PMID 32700396, PMID 34793923, PMID 35070788, PMID 35164816, PMID 35763768, PMID 36243263, PMID 36645250, PMID 36854592, PMID 38012327, PMID 388439, PMID 38997668, PMID 39926308, PMID 39957001, PMID 40130283, PMID 40548131, PMID 41436274, PMID 5432063, PMID 7503400, PMID 942051
2017 (1), R01HL159803 (1)