16 completed, 4 recruiting, 4 terminated, 3 not yet recruiting. 15 Not applicable, 4 Phase 2, 2 Phase 1, 2 Phase 4, 1 Phase 3.
Follow Cardiorenal Syndrome: new trials by email Literature Review of Cardiorenal Syndrome trials Research Report on Cardiorenal Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cardiorenal Syndrome: Characteristics and Prognostic Impact in Advanced Heart Failure Cardiorenal syndrome follow-up - Advanced Heart Failure, Cardiorenal Syndrome | Not applicable | Not yet recruiting | Hospices Civils de Lyon | 100 | 2026-09-01 | 2026-07-01 |
| Monitoring of the Sympathetic/Vagal Balance Through Multiparametric Analysis of Heart Rate Variability (HRV) HOLTER ECG monitoring - Diabete Type 2, Heart Failure | Active not recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 150 | 2026-05-20 | 2026-09-04 | |
| French AKI Registry (FAKIR): A Multicenter Study on the In-Hospital Management and Outcomes of Severe Acute Kidney Injury in Nephrology Units Acute Kidney Injury, Kidney Failure Chronic | Not yet recruiting | University Hospital, Strasbourg, France | 750 | 2025-11-01 | 2025-08-14 | |
| Feasibility of the SCD in Cardiorenal Syndrome Patients Awaiting LVAD Selective Cytopheretic Device - Acute on Chronic Systolic Congestive Heart Failure, Cardiorenal Syndrome | Not applicable | Recruiting | SeaStar Medical | 20 | 2025-10-02 | 2026-03-31 |
| Exercise Rehabilitation for Cardiorenal Syndrome in HFrEF Patients Standardized Basic Drug Therapy for HFrEF with Chronic Kidney Dysfunction, Home-based Personalized Exercise Rehabilitation - Cardiorenal Syndrome | Not applicable | Recruiting | Haiyan Pan | 60 | 2025-09-15 | 2026-02-27 |
| SCD for CRS in Congestive Heart Failure (CHF) (No Left Ventricular Assist Device) Selective Cytopheretic Device - Heart Failure, Chronic Systolic Heart Failure | Not applicable | Suspended | Lenar Yessayan | 10 | 2025-09-01 | 2024-09-27 |
| Effects of a Supervised Training Program on Functional Capacity in Patients With HF and Cardiorenal Syndrome Supervised aerobic plus strength training - Heart Failure, Cardiorenal Syndrome | Not applicable | Not yet recruiting | Fundación para la Investigación del Hospital Clínico de Valencia | 26 | 2024-10-08 | 2024-10-15 |
| Venous Ultrasound Guided Organ Decongestion in Patients Hospitalized with Acute Decompensated Heart Failure VExUS guided decongestion - Cardiorenal Syndrome, Heart Failure | Not applicable | Recruiting | Oslo University Hospital | 180 | 2024-09-16 | 2024-12-03 |
| Feasibility Study to Support Cardiorenal Function in Acute Decompensated Heart Failure With Diuretic Resistance ModulHeart Support - Heart Failure, Acute Decompensated Heart Failure | Not applicable | Unknown | Puzzle Medical Devices Inc. | 5 | 2024-08-01 | 2024-06-17 |
| Sodium-Glucose Cotransporter-2 Inhibitor for Acute Cardiorenal Syndrome: A Feasibility Study Dapagliflozin - Cardiorenal Syndrome | Phase 2 | Completed | Yale University | 30 | 2024-05-30 | 2026-08-13 |
| Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure Aortix System - Heart Failure, Cardiorenal Syndrome | Not applicable | Recruiting | Procyrion | 320 | 2023-08-23 | 2026-08-25 |
| Cardiorenal and Metabolic Effects of Nighttime Eating Dietary - Night Eating Syndrome, Metabolic Syndrome | Not applicable | Completed | Koc University Hospital | 16 | 2022-05-01 | 2025-08-26 |
| Effect on Kidney Function Recovery Guiding Decongestion With VExUS in Patients With Cardiorenal Syndrome 1 Vexus, Control group - Cardiorenal Syndrome, Acute Kidney Injury | Not applicable | Completed | Hospital Civil de Guadalajara | 140 | 2022-03-20 | 2023-07-10 |
| The Aortix CRS Pilot Study Aortix System - Heart Failure; With Decompensation, Cardiorenal Syndrome | Not applicable | Completed | Procyrion | 21 | 2021-02-05 | 2024-04-17 |
| Volume Optimization Incorporating Negative Pressure Diuresis in Heart Failure (VOID-HF) JuxtaFlow System - Cardiorenal Syndrome | Not applicable | Completed | 3ive Labs | 8 | 2020-06-12 | 2023-10-25 |
| Alfapump Direct Sodium Removal (DSR) Feasibility Study alfapump DSR system - Heart Failure, Congestive Heart Failure | Not applicable | Completed | Sequana Medical N.V. | 8 | 2019-12-26 | 2021-05-28 |
| Renal Venous Flow and Cardiac Surgery-associated Acute Kidney Injury No intervention - Acute Kidney Injury, Cardiorenal Syndrome | Completed | University of Giessen | 200 | 2018-12-20 | 2023-12-01 | |
| Association Between Renal and Right Cardiac Functions After Urinary Sodium Depletion Following Cardiac Surgery diuretic use - Cardiorenal Syndrome | Terminated | Centre Hospitalier Universitaire, Amiens | 9 | 2018-06-01 | 2026-06-25 | |
| The Effect in Renal Function on Patients With Type 1 Cardiorenal Syndrome Treated With Two Strategies of Furosemide. Furosemide intravenous solution, Chlortalidone, Spironolactone - Cardiorenal Syndrome | Phase 2 | Completed | Hospital Civil de Guadalajara | 80 | 2017-07-01 | 2020-09-14 |
| Implementation of Telerehabilitation In Support of HOme-based Physical Exercise for Heart Failure Telerehabilitation - Heart Failure, Systolic, Heart Failure, Diastolic | Not applicable | Completed | Helse Nord-Trøndelag HF | 61 | 2017-06-08 | 2022-04-14 |
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Cardio-Renal Syndrome (32) · Heart Failure (11) · Acute Kidney Injury (5) · Renal Insufficiency, Chronic (4) · Heart Failure, Diastolic (3) · Heart Failure, Systolic (3) · Hyperemia (3) · Renal Insufficiency (3) · Edema (2) · Diabetes Mellitus, Type 2 (1) · Heart Diseases (1) · Hypernatremia (1) · Hypertension, Pulmonary (1) · Kidney Failure, Chronic (1) · Metabolic Syndrome (1)
Cardiovascular Diseases (32) · Female Urogenital Diseases (32) · Female Urogenital Diseases and Pregnancy Complications (32) · Kidney Diseases (32) · Male Urogenital Diseases (32) · Urogenital Diseases (32) · Urologic Diseases (32) · Heart Diseases (31) · Renal Insufficiency (29) · Heart Failure (21) · Pathological Conditions, Signs and Symptoms (9) · Pathologic Processes (6) · Chronic Disease (5) · Disease Attributes (5) · Vascular Diseases (4)
Diet (2) · Dobutamine (2) · Natriuretic Peptide, Brain (2) · Simendan (2) · Alendronate (1) · Calcitriol (1) · Chlorthalidone (1) · Cholecalciferol (1) · Control Groups (1) · Dietary Supplements (1) · Doxycycline (1) · Electrocardiography, Ambulatory (1) · Food (1) · Furosemide (1) · Milrinone (1)
Hospital Civil de Guadalajara (2) · Procyrion (2) · University of Giessen (2) · 3ive Labs (1) · Ankara University (1) · Centre Hospitalier Universitaire, Amiens (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Fundación para la Investigación del Hospital Clínico de Valencia (1) · Göteborg University (1) · Haiyan Pan (1) · Helse Nord-Trøndelag HF (1) · Hillel Yaffe Medical Center (1) · Horng Chen (1) · Hospices Civils de Lyon (1) · Koc University Hospital (1)
United States (11) · Australia (2) · France (2) · Georgia (2) · Germany (2) · Italy (2) · Mexico (2) · Norway (2) · Turkey (Türkiye) (2) · Belgium (1) · Brazil (1) · China (1) · Hungary (1) · Israel (1) · Netherlands (1)
Abinet Aklilu (1) · Alex Parker, MD (1) · Alexander Kharlamov, M.D. (1) · Alexander Perrish, M.D. (1) · Donatella Brisinda, MD (1) · Evandro T Mesquita, PhD (1) · Havard Dalen, MD, PhD (1) · Horng H. Chen, M.D. (1) · Horst-Walter Birk, M.D. (1) · James L Januzzi, MD (1) · Jozef Bartunek, MD (1) · Karan Wats, MBBS (1) · Keith Aaronson, MD (1)
PMID 27179835, PMID 34979962, PMID 10889132, PMID 15769768, PMID 16461840, PMID 19318356, PMID 22839442, PMID 23247571, PMID 24578332, PMID 26989397, PMID 27592046, PMID 28711449, PMID 28785469, PMID 30369310, PMID 30371304, PMID 30429498, PMID 31630601, PMID 33258308, PMID 34261129, PMID 37221704, PMID 37577933, PMID 37804307, PMID 38061346, PMID 38556717, PMID 39282762, PMID 39501477
R44HL170779 (1)