7 terminated, 5 withdrawn, 4 completed. 16 Phase 3, 11 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 16 | Terminated 7, Withdrawn 5, Completed 4 |
| Phase 2 | 11 | Terminated 6, Withdrawn 3, Completed 2 |
Follow Burn: new trials by email Literature Review of Burn trials Research Report on Burn
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fenofibrate and Propranolol in Burn Patients Fenofibrate, Placebo, Propranolol - Burn | Phase 2 / Phase 3 | Terminated | The University of Texas Medical Branch, Galveston | 18 | 2015-11-01 | 2019-11-29 |
| Propranolol in Severely Burned Children Propranolol, Placebo - Burn | Phase 2 / Phase 3 | Terminated | The University of Texas Medical Branch, Galveston | 63 | 2013-12-01 | 2019-09-24 |
| Protective Effects of Propranolol in Adults Propranolol, Placebo - Burn | Phase 2 / Phase 3 | Terminated | The University of Texas Medical Branch, Galveston | 47 | 2013-07-01 | 2019-11-29 |
| Vitamin E Supplementation in Burned Patients Vitamin E - Burn | Phase 2 / Phase 3 | Completed | The University of Texas Medical Branch, Galveston | 27 | 2013-02-01 | 2026-07-20 |
| Epidermal Cells Delivery and Acute Burns autologous epidermal cells harvesting kits, classic skin grafts - Burn | Phase 3 | Terminated | Assistance Publique - Hôpitaux de Paris | 51 | 2008-12-01 | 2012-07-26 |
| Mitochondrial Oxidation and Insulin Resistance in Burn Patients Treated With Fenofibrate fenofibrate, placebo - Burn | Phase 2 / Phase 3 | Withdrawn | The University of Texas Medical Branch, Galveston | 2008-08-01 | 2012-12-11 | |
| High-Dose Vitamin D Deficiency in Burn Injury Vitamin D - Burn | Phase 3 | Withdrawn | The University of Texas Medical Branch, Galveston | 2007-02-01 | 2012-11-15 | |
| Trial of Zesteem (Estradiol) in Healing of Split Thickness Skin Graft Donor Sites estradiol (Zesteem) - Burn, Trauma | Phase 3 | Completed | Renovo | 148 | 2007-01-01 | 2009-08-28 |
| New Treatment for Donor Sites Application of donor site dressing [scarlet red, Microbial Nanocellulose (NC), or hyaluronan and thrombin (HT)], Blood sample, Biopsy - Burn | Phase 2 / Phase 3 | Withdrawn | The University of Texas Medical Branch, Galveston | 2006-01-01 | 2012-12-11 | |
| Enzymatic Debridement in Burns Patients: A Comparison to Standard of Care DGD - Burn | Phase 3 | Completed | MediWound Ltd | 182 | 2005-12-01 | 2011-05-10 |
| Evaluation Perioperative Nutrition on Donor Site Healing in Patients Undergoing Reconstructive Burn Surg Juven (Ross Products) protein supplement - Burn, Reconstructive Surgical Procedure | Phase 2 / Phase 3 | Terminated | Shriners Hospitals for Children | 38 | 2005-06-01 | 2012-06-19 |
| Use of Amnion on Partial Thickness Burns Amnion, Polysporin/Bacitracin/Mycostatin - Burn | Phase 2 / Phase 3 | Withdrawn | The University of Texas Medical Branch, Galveston | 2005-06-01 | 2012-11-15 | |
| Virtual Reality Pain Control During Burn Wound Care Virtual Reality Distraction - Burn | Phase 2 / Phase 3 | Completed | National Institute of General Medical Sciences (NIGMS) | 184 | 2002-02-01 | 2013-04-19 |
| Study of the Treatment of Burn Wounds With Antimicrobial Topical Soaks Sulfamylon 5% and Silver Nitrate Soaks - Burn | Phase 2 / Phase 3 | Terminated | The University of Texas Medical Branch, Galveston | 98 | 1995-07-01 | 2023-06-22 |
| Bone Disease in Severely Burned Children Tetracycline, Duel Energy X-Ray Absorptiometry (DEXA), Bone Biopsy - Burn | Phase 2 / Phase 3 | Terminated | The University of Texas Medical Branch, Galveston | 254 | 1992-10-01 | 2014-06-06 |
| Intron A for the Treatment of Hypertrophic Scar interferon alpha 2b - Burn, Hypertrophic Scar | Phase 3 | Withdrawn | University of Alberta | 2014-01-30 |
Burns (16) · Wounds and Injuries (3) · Cicatrix (1) · Cicatrix, Hypertrophic (1) · Inflammation (1) · Insulin Resistance (1) · Varicose Ulcer (1) · Wound Infection (1)
Wounds and Injuries (13) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Fibrosis (2) · Cardiovascular Diseases (1) · Cicatrix (1) · Glucose Metabolism Disorders (1) · Hyperinsulinism (1) · Infections (1) · Leg Ulcer (1) · Metabolic Diseases (1) · Nutritional and Metabolic Diseases (1) · Skin Diseases (1) · Skin Ulcer (1) · Skin and Connective Tissue Diseases (1)
Metoprolol (3) · Propranolol (3) · Fenofibrate (2) · Biopsy (1) · Blood Specimen Collection (1) · Estradiol (1) · Hyaluronic Acid (1) · Interferon alpha-2 (1) · Introns (1) · Mafenide (1) · Scarlet Red (1) · Silver Nitrate (1) · Tetracycline (1) · Thrombin (1) · Vitamin D (1)
The University of Texas Medical Branch, Galveston (10) · Assistance Publique - Hôpitaux de Paris (1) · MediWound Ltd (1) · National Institute of General Medical Sciences (NIGMS) (1) · Renovo (1) · Shriners Hospitals for Children (1) · University of Alberta (1)
United States (8) · Canada (2) · France (2) · Germany (2) · United Kingdom (2) · Australia (1) · Brazil (1) · Israel (1) · Italy (1) · Latvia (1) · Poland (1) · Romania (1) · Russia (1) · Slovakia (1)
David N Herndon, MD (7) · David Herndon, MD (1) · David R. Patterson, Ph.D. (1) · Edward E Tredget, MD MSc FRCSC (1) · Ken Dunn, MD (1) · Klein Gordon, M.D. (1) · Linda E Sousse, PhD, MBA (1) · Lior Rosenberg, MD (1) · Perenlei Enkhbaatar, MD, PhD (1) · Theresa M Mayes, RD,LD (1)
PMID 17245174, PMID 24074719, PMID 38837237
R01GM042725 (1)