19 completed, 2 terminated, 2 unknown, 1 not yet recruiting. 6 Not applicable, 5 Phase 2, 3 Phase 4, 2 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 4, Recruiting 1, Unknown 1 |
| Phase 2 | 5 | Completed 5 |
| Phase 4 | 3 | Completed 2, Terminated 1 |
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 1, Terminated 1 |
Follow Bronchospasm: new trials by email Literature Review of Bronchospasm trials Research Report on Bronchospasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Perioperative Respiratory Adverse Events in Cleft Lip and Palate Surgery: Incidence, Risk Factors, and Clinical Scoring Standard General Anesthesia per Institutional Protocol - Cleft Palate, Cleft Lip | Not yet recruiting | Marmara University Pendik Training and Research Hospital | 150 | 2026-06-27 | 2026-06-16 | |
| Intraoperative Paravertebral Block and Postoperative Complications Paravertebral Block (PVB) - Video-assisted Thoracoscopic Surgery (VATS), Lung Cancer (Diagnosis) | Not applicable | Recruiting | Tongji Hospital | 500 | 2025-03-25 | 2025-10-08 |
| Wei Nasal Jet Tube vs Nasal Cannula Oxygen Support in Gastrointestinal Endoscopy Patients Wei Nasal Jet Tube, Nasal Cannula Oxygen Support - Supraglottic Airway Obstruction, Airway Complication of Anesthesia | Not applicable | Completed | Bezmialem Vakif University | 100 | 2023-03-30 | 2024-08-12 |
| INHALATION CHAMBER MANAGEMENT IN PEDIATRICS: EFFICACY OF AN EDUCATIONAL INTERVENTION IN PATIENTS DIAGNOSED WITH BRONCHOSPASM AND THEIR FAMILY CAREGIVERS. educational intervention - Bronchospasm | Not applicable | Completed | Puerta de Hierro University Hospital | 134 | 2023-01-10 | 2026-09-09 |
| Wei Nasal Jet Tube vs Gastro Laryngeal Tube in Endoscopic Retrograde Cholangiopancreatography Wei Nasal Jet Tube, Gastro Laryngeal Tube - Supraglottic Airway Efficiency, Airway Complication of Anesthesia | Not applicable | Completed | Bezmialem Vakif University | 114 | 2022-05-10 | 2022-09-15 |
| Bronchospasm During Anesthetic Induction: Study of Clinical Characteristics and Treatments Administered According to Etiology Bronchospasm | Completed | Central Hospital, Nancy, France | 31 | 2020-09-01 | 2021-08-27 | |
| Avoiding Neuromuscular Blockers to Reduce Complications Neuromuscular Blocking Agents, Anesthetic Adjuncts - Respiratory Failure, Respiratory Infection | Phase 4 | Terminated | Beth Israel Deaconess Medical Center | 3 | 2019-08-07 | 2026-06-04 |
| Efficacy and Safety of Continuous Infusion of Ketamine in Pediatric Intensive Care Unit (KISS Study) Analgesia, Ketamine Toxicity | Completed | Azienda Ospedaliera di Padova | 57 | 2019-04-01 | 2022-02-15 | |
| Virtual Teach-to-Goal Education vs. Brief Education for Children Virtual Teach to Goal, Brief Intervention - Asthma, Bronchospasm | Not applicable | Completed | University of Chicago | 70 | 2019-01-16 | 2021-04-29 |
| Change of Regional Ventilation During Spontaneous Breathing After Lung Surgery Perioperative pulmonary function tests - Pulmonary Infection, Respiratory Insufficiency | Completed | Wuerzburg University Hospital | 31 | 2016-06-01 | 2017-11-06 | |
| Driving Pressure And EFL in Adult Cardiac Surgery Respiratory Failure, Pneumothorax | Completed | Ospedale San Raffaele | 200 | 2015-11-01 | 2017-05-23 | |
| Ketamine Efficacy for Acute Severe Bronchospasm in ICU: MACANUDO Trial Ketamine, Fentanyl - Critical Illness, Asthma | Phase 2 / Phase 3 | Completed | Hospital Nossa Senhora da Conceicao | 45 | 2015-06-04 | 2024-05-21 |
| Perioperative Change of Regional Ventilation During Spontaneous Breathing Perioperative pulmonary function tests - Pulmonary Infection, Pleural Effusion | Completed | Wuerzburg University Hospital | 72 | 2015-01-01 | 2016-03-01 | |
| Mechanical Ventilation During Cardiac Surgery Non-ventilation during CPB, Ventilation with CPAP, Ventilation with 5 act/minute - Respiratory Failure, Pneumothorax | Not applicable | Unknown | Ospedale San Raffaele | 780 | 2014-11-01 | 2016-02-02 |
| Observational Study on Obese Patients During General Anesthesia Bronchospasm, Surgery | Unknown | Larissa University Hospital | 50 | 2011-03-01 | 2011-12-08 | |
| Epinephrine Inhalation Aerosol USP, a HFA-MDI Study for Assessment of Pharmacokinetics Epinephrine Inhalation Aerosol, HFA, Epinephrine Inhalation Aerosol - Asthma, Bronchospasm | Phase 1 / Phase 2 | Completed | Amphastar Pharmaceuticals, Inc. | 23 | 2010-08-01 | 2017-07-25 |
| Escalating and Cumulative-Dose Study of Pharmacokinetics (PK), Pharmacodynamics (PD) and Safety of A006 A006, Placebo DPI, Proventil-HFA - Asthma, Bronchospasm | Phase 2 | Completed | Amphastar Pharmaceuticals, Inc. | 27 | 2010-07-01 | 2017-07-02 |
| Dose-Ranging Study of A006 DPI, in Adult Asthma Patients albuterol inhalation powder, Placebo, albuterol inhalation aerosol - Asthma, Bronchospasm | Phase 2 | Completed | Amphastar Pharmaceuticals, Inc. | 26 | 2010-07-01 | 2017-04-19 |
| Prophylactic Efficacy of Relenza Against Influenza A and B Receiving a prescription of Relenza for prophylaxis, No prophylaxis with Relenza - Pulmonary Disease, Chronic Obstructive, Bronchospasm | Completed | GlaxoSmithKline | 171705 | 2009-07-01 | 2017-05-30 | |
| A Randomized, Double-Blind, Placebo-Controlled Study of Omalizumab for Idiopathic Anaphylaxis Epinephrine, Omalizumab (Xolair), Placebos - Anaphylaxis, Hypotension | Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 16 | 2009-04-27 | 2019-07-01 |
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Bronchial Spasm (25) · Asthma (9) · Pulmonary Atelectasis (6) · Respiratory Insufficiency (6) · Pneumonia, Aspiration (4) · Pneumothorax (4) · Pulmonary Disease, Chronic Obstructive (3) · Airway Obstruction (2) · Anaphylaxis (2) · Asthma, Exercise-Induced (2) · Dyspnea (2) · Epistaxis (2) · Hypersensitivity (2) · Motor Activity (2) · Pleural Effusion (2)
Bronchial Diseases (25) · Respiratory Tract Diseases (25) · Lung Diseases (16) · Pathological Conditions, Signs and Symptoms (12) · Hypersensitivity, Immediate (11) · Immune System Diseases (11) · Respiration Disorders (10) · Hypersensitivity (9) · Lung Diseases, Obstructive (9) · Respiratory Hypersensitivity (9) · Pathologic Processes (8) · Infections (6) · Signs and Symptoms (6) · Disease Attributes (4) · Otorhinolaryngologic Diseases (4)
Albuterol (3) · Epinephrine (2) · Fluticasone-Salmeterol Drug Combination (2) · Ketamine (2) · Analgesics, Opioid (1) · Crisis Intervention (1) · Dexmedetomidine (1) · Early Intervention, Educational (1) · Fentanyl (1) · Fluticasone (1) · Inhalation (1) · Neuromuscular Blocking Agents (1) · OIC-A006 (1) · Omalizumab (1) · Propofol (1)
Amphastar Pharmaceuticals, Inc. (4) · GlaxoSmithKline (4) · Bezmialem Vakif University (2) · Ospedale San Raffaele (2) · Wuerzburg University Hospital (2) · Azienda Ospedaliera di Padova (1) · Beth Israel Deaconess Medical Center (1) · Central Hospital, Nancy, France (1) · Hospital Nossa Senhora da Conceicao (1) · Larissa University Hospital (1) · Marmara University Pendik Training and Research Hospital (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Ohio State University (1) · Puerta de Hierro University Hospital (1) · Tongji Hospital (1)
United States (10) · Italy (3) · Germany (2) · Turkey (Türkiye) (2) · Brazil (1) · China (1) · France (1) · Greece (1) · Spain (1) · United Kingdom (1)
Elena Bignami, MD (2) · Harun Uysal, M.D. (1) · John G. Mastronarde, MD (1) · Markus Kredel, PD. Dr. med (1) · Markus Kredel, PD.Dr.med (1) · Maximilian S Schaefer, MD (1) · Melody C Carter, M.D. (1)
PMID 26036953, PMID 28592276, PMID 31351452, PMID 32423275, PMID 36870528