6 completed, 2 terminated, 1 not yet recruiting, 1 unknown. 10 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 6, Terminated 2, Not yet recruiting 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Bariatric Surgery: new trials by email Literature Review of Bariatric Surgery trials Research Report on Bariatric Surgery
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oxytocin for Respiratory Compromise and Hypoventilation Induced by Drugs Intranasal Oxytocin 40 i.u., Intranasal Placebo Spray - Obesity & Overweight, Respiratory Depression | Phase 2 | Not yet recruiting | George Washington University | 100 | 2027-05-15 | 2026-10-29 |
| Oral Acetaminophen for Post-Op Pain Management in Bariatric Surgery Patients Acetaminophen - Post Operative Analgesia, Bariatric Surgery | Phase 2 | Completed | Rutgers, The State University of New Jersey | 65 | 2024-11-13 | 2026-08-24 |
| Study to Evaluate ARD-101 in Adults Receiving Bariatric Surgery ARD-101 - Bariatric Surgery, Obesity | Phase 2 | Completed | Aardvark Therapeutics, Inc. | 12 | 2022-03-01 | 2025-02-11 |
| Naldebain for Pain Control After Bariatric Surgery Dinalbuphine sebacate, Placebo solution - Pain, Postoperative, Pain, Chronic | Phase 2 / Phase 3 | Unknown | E-DA Hospital | 60 | 2021-06-24 | 2021-12-28 |
| Zoledronic Acid for Prevention of Bone Loss After BAriatric Surgery (ZABAS) Zoledronic Acid, Placebo - Bone Loss, Muscle Atrophy | Phase 2 | Completed | Stinus Gadegaard Hansen | 59 | 2021-02-20 | 2026-06-01 |
| Adjunct Phentermine + Topiramate After Bariatric Surgery in 12-24 Year Olds Phentermine, Immediate Release Topiramate, Placebo for Phentermine - Obesity, Morbid, Bariatric Surgery | Phase 2 | Completed | University of Colorado, Denver | 13 | 2020-01-15 | 2025-05-23 |
| Rivaroxaban as Thrombosis Prophylaxis in Bariatric Surgery Rivaroxaban 10 MG Oral Tablet [Xarelto] - Bariatric Surgery | Phase 2 | Completed | Insel Gruppe AG, University Hospital Bern | 272 | 2018-07-19 | 2024-11-13 |
| Regional TAP Block for Bariatric Patients Transverse abdominal plane block, Ropivacaine - Bariatric Surgery, Transverse Abdominal Plane Regional Blocks | Phase 1 / Phase 2 | Completed | Montefiore Medical Center | 23 | 2013-04-01 | 2019-12-03 |
| Effects of Caloric Restriction Alone Versus Postoperative Caloric Restriction Following Bariatric Surgery on Glucose Metabolism in Patients With Diabetes Mellitus Roux-en-Y Gastric Bypass, Caloric Restriction - Obesity, Bariatric Surgery | Phase 2 | Terminated | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 5 | 2011-03-31 | 2019-12-17 |
| The Effect of Surgically Induced Weight Loss on Endocrine Function, Cardiovascular Function and Body Composition GLP-1 - Bariatric Surgery | Phase 2 | Terminated | Johns Hopkins University | 51 | 2007-05-01 | 2017-07-02 |
Obesity (4) · Obesity, Morbid (2) · Agnosia (1) · Bone Diseases, Metabolic (1) · Chronic Pain (1) · Diabetes Mellitus, Type 2 (1) · Muscular Atrophy (1) · Obesity Hypoventilation Syndrome (1) · Overweight (1) · Pain, Postoperative (1) · Respiratory Insufficiency (1) · Venous Thromboembolism (1) · Weight Gain (1)
Pathological Conditions, Signs and Symptoms (7) · Signs and Symptoms (7) · Nutritional and Metabolic Diseases (6) · Body Weight (5) · Nutrition Disorders (5) · Overnutrition (5) · Overweight (4) · Nervous System Diseases (3) · Neurologic Manifestations (3) · Metabolic Diseases (2) · Apnea (1) · Atrophy (1) · Body Weight Changes (1) · Bone Diseases (1) · Cardiovascular Diseases (1)
Acetaminophen (1) · Caloric Restriction (1) · Gastric Bypass (1) · Glucagon-Like Peptide 1 (1) · Phentermine (1) · Rivaroxaban (1) · Ropivacaine (1) · Tablets (1) · Topiramate (1) · Zoledronic Acid (1) · sebacoyl dinalbuphine ester (1)
Aardvark Therapeutics, Inc. (1) · E-DA Hospital (1) · George Washington University (1) · Insel Gruppe AG, University Hospital Bern (1) · Johns Hopkins University (1) · Montefiore Medical Center (1) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1) · Rutgers, The State University of New Jersey (1) · Stinus Gadegaard Hansen (1) · University of Colorado, Denver (1)
United States (6) · Denmark (1) · Switzerland (1) · Taiwan (1)
Chen-Fuh Lam, MD, PhD (1) · Daniel T Abazia, PharmD (1) · Dariush Elahi, PhD (1) · Guido Stirnimann, MD (1) · Jaime M Moore, MD, MPH (1) · Karina Gritsenko, MD (1) · Kristina I Rother, M.D. (1)
PMID 36209245, PMID 36413425, PMID 37227726, PMID 41177144
P30DK048520 (1), UG3DA062506-02 (1)