34 completed, 11 unknown, 3 recruiting, 2 not yet recruiting. 34 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 34 | Completed 22, Unknown 6, Recruiting 2, Active not recruiting 1, Enrolling by invitation 1, Not yet recruiting 1, Withdrawn 1 |
| Phase 2 | 1 | Completed 1 |
Follow Autonomic Nervous System: new trials by email Literature Review of Autonomic Nervous System trials Research Report on Autonomic Nervous System
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Heart Rate Variability and Medication Adherence in Resistant Hypertension Heart rate variability recording (Polar H10) ·, Therapeutic drug monitoring (antihypertensive drug levels), Questionnaires (MARS-CZ, PHQ-9, SF-36, IPAQ) - Resistant Hypertension, Medication Adherence | Not yet recruiting | Nemocnice AGEL Trinec-Podlesi a.s. | 150 | 2026-07-20 | 2026-07-16 | |
| PSYLIVER-PILOTE: Involvement of the Autonomic Nervous System in Hepatocellular Carcinoma (HCC) Measurements of autonomic nervous system (ANS) activity at rest and during sensory stimulation., Self-administered questionnaires to assess psycho-behavioral traits, Analysis of nocturnal cardiac activity (at home): electrocardiographic (ECG) recording of heart activity during one night. - Hepato Cellular Carcinoma, Cirrhosis | Not applicable | Recruiting | Hospices Civils de Lyon | 100 | 2026-04-17 | 2026-04-29 |
| Effect of Hot Spring Therapy on Autonomic Nervous System and Exercise Performance During Altitude Training Control Group：Natural Recovery, Hot water immersion group, hot spring immersion group - Altitude Training Adaptation, Autonomic Nervous System | Not applicable | Completed | Macao Polytechnic University | 27 | 2026-01-10 | 2026-06-26 |
| Frequency-Dependent Effects of Auricular Vagus Nerve Stimulation on Autonomic and Cardiovascular Parameters Pulsetto FIT™ - Sham tcVNS, Pulsetto FIT™ - tcVNS 10 Hz, Pulsetto FIT™ - tcVNS 25 Hz - Vagus Nerve Stimulation, Autonomic Nervous System | Not applicable | Not yet recruiting | SEFA HAKTAN HATIK | 36 | 2025-12-22 | 2025-12-10 |
| App-based Breathing Program for Migraine Relief Baseline Survey, Heart rate variability biofeedback, Sham Control Group - Migraine, Heart Rate Variability (HRV) | Not applicable | Enrolling by invitation | Arizona State University | 30 | 2025-12-15 | 2026-07-23 |
| Mandibular Stretching and 4-4-8 Breathing Exercises on Autonomic Nervous System Activity Mandibular Stretching Exercise, 4-4-8 Breathing Exercise - Muscle Tone, Psychological State | Not applicable | Recruiting | Mehin Mammadzada | 52 | 2025-12-15 | 2026-03-16 |
| Vagus Nerve Stimulator for Autism and Other Developmental Disorders Vagus Nerve Stimulation - Autism Spectrum Disorder, Intellectual Disability | Not applicable | Withdrawn | New York State Institute for Basic Research | 2025-05-01 | 2026-02-13 | |
| Effects of Active Stretching on Cardiovascular Response and Arterial Stiffness in Older Adults With Low Flexibility Active Static Stretching Exercise Combined with Breathing Exercise (Experimental Group) - Arterial Stiffness, Autonomic Nervous System | Not applicable | Completed | University of Phayao | 80 | 2024-12-01 | 2025-04-25 |
| Autonomic Nervous System Dysregulation in People With Chronic Neck Pain Isometric hand grip test - Chronic Neck Pain, Autonomic Nervous System | Completed | National Yang Ming Chiao Tung University | 56 | 2024-09-29 | 2025-12-10 | |
| Effect of an Aerobic Exercise Session on Cardiovascular and Autonomic Parameters of Adults With Hypertrophic Cardiomyopathy Exercise - Cardiomyopathy, Hypertrophic, Physical Exercise | Not applicable | Active not recruiting | Instituto de Cardiologia do Rio Grande do Sul | 10 | 2024-07-29 | 2025-08-17 |
| Effects of a Smart Circuit Exercise Program on Health Outcomes in Community-Dwelling Older Adults Smart Circuit Exercise Program - Aging, Autonomic Nervous System | Not applicable | Completed | Chang Gung Memorial Hospital | 256 | 2024-05-10 | 2026-08-27 |
| Effect Of Robotic Rehabilitation And Vagus Nerve Stimulation In Ischemia Stroke Patients Robotic Rehabilitation, Transcutaneous Auricular Vagal Nerve Stimulation - Ischemic Stroke, Vagus Nerve Stimulation | Not applicable | Unknown | SEFA HAKTAN HATIK | 40 | 2024-05-10 | 2024-04-24 |
| The Efficacy of Aerobic Exercise Training on ANS and Endothelial Function in Compensated Cirrhosis Aerobic exercise + Nutrition consultant, Nutrition consultant - Cirrhosis, Aerobic Exercises | Not applicable | Completed | King Chulalongkorn Memorial Hospital | 50 | 2024-03-12 | 2026-05-22 |
| Evaluation of the Response to Hypoxia at Rest and During Exercise in a Healthy Subject After a Cryostimulation Exposure Cryostimulation - Hypoxia, Cryostimulation | Not applicable | Unknown | Poitiers University Hospital | 35 | 2024-01-25 | 2024-01-26 |
| The Effects of Heart Rate Variability Biofeedback on College Students With Disordered Eating Baseline survey, Heart rate variability biofeedback, Educational materials - Eating Disorders, Eating, Binge | Not applicable | Completed | Arizona State University | 21 | 2024-01-08 | 2024-09-19 |
| Autonomic and Cardiovascular Recovery After the Acute Use of Resveratrol in Overweight and Obesity Individuals Resveratrol Experimental - Polyphenols, Cardiovascular Diseases | Not applicable | Unknown | Taisy Cinthia Ferro Cavalcante | 30 | 2023-08-01 | 2023-08-31 |
| Cardiovascular and Cerebrovascular Control in Healthy Subjects active standing - Healthy, Autonomic Nervous System | Recruiting | IRCCS Policlinico S. Donato | 60 | 2023-05-29 | 2026-07-06 | |
| Feldenkrais Method and Stress-Related Responses in Adult Women Feldenkrais Method - Awareness Through Movement (ATM) - Stress, Psychological, Autonomic Nervous System | Not applicable | Completed | University of Palermo | 24 | 2023-04-01 | 2025-09-16 |
| Longitudinal Evolution of Biomarkers of Dysautonomia and Inflammation During Sepsis in Children Ambulatory ECG, Blood sample - Sepsis, Autonomic Nervous System | Unknown | Centre Hospitalier Universitaire de Saint Etienne | 60 | 2023-03-29 | 2024-05-03 | |
| Acute Nerve Stimulation For Enhancing Human and Cognitive Performance Experimental group with 100% intensity setting on Apollo Neuro device, Active Comparator group with 10% intensity setting on the Apollo Neuro device - Concussion, Mild, Autonomic Nervous System | Not applicable | Completed | University of South Carolina | 35 | 2023-01-15 | 2024-03-28 |
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Motor Activity (5) · Emotional Regulation (2) · Fibrosis (2) · Hypertension (2) · Respiratory Aspiration (2) · Acute Coronary Syndrome (1) · Agnosia (1) · Altitude Sickness (1) · Anorexia Nervosa (1) · Atrial Fibrillation (1) · Autism Spectrum Disorder (1) · Autonomic Nervous System Diseases (1) · Benign Paroxysmal Positional Vertigo (1) · Binge-Eating Disorder (1) · Bradycardia (1)
Pathological Conditions, Signs and Symptoms (13) · Nervous System Diseases (10) · Behavior (9) · Signs and Symptoms (8) · Cardiovascular Diseases (7) · Pathologic Processes (7) · Neurologic Manifestations (6) · Brain Diseases (5) · Central Nervous System Diseases (5) · Vascular Diseases (5) · Heart Diseases (4) · Respiratory Tract Diseases (4) · Respiration Disorders (3) · Arrhythmias, Cardiac (2) · Cerebrovascular Disorders (2)
Surveys and Questionnaires (4) · Caffeine (3) · Vagus Nerve Stimulation (3) · Breathing Exercises (2) · Exercise (2) · Adrenocorticotropic Hormone (1) · Blood Specimen Collection (1) · Coronary Artery Bypass (1) · Cosyntropin (1) · Dexmedetomidine (1) · Diet (1) · Doxazosin (1) · Drug Monitoring (1) · Exercise Test (1) · Muscle Stretching Exercises (1)
Arizona State University (3) · Larissa University Hospital (3) · Centre Hospitalier Universitaire de Saint Etienne (2) · Instituto de Cardiologia do Rio Grande do Sul (2) · SEFA HAKTAN HATIK (2) · Universidade Estadual Paulista Júlio de Mesquita Filho (2) · ARCIM Institute Academic Research in Complementary and Integrative Medicine (1) · ASST Fatebenefratelli Sacco (1) · Ajou University School of Medicine (1) · Brigham and Women's Hospital (1) · Centre Hospitalier Universitaire de Besancon (1) · Chang Gung Memorial Hospital (1) · Clalit Health Services (1) · Ege University (1) · Hospices Civils de Lyon (1)
United States (9) · Brazil (6) · France (5) · Turkey (Türkiye) (5) · Greece (3) · Italy (3) · Spain (3) · Taiwan (3) · Israel (2) · Thailand (2) · Belgium (1) · China (1) · Czechia (1) · Germany (1) · Poland (1)
George Vretzakis, Medicine (3) · Marina Simaioforidou, Medicine (2) · Aikaterini Tsiaka, Medicine (1) · Arlene R Welch, BS, DC (1) · Athanasios Drakos, Medicine (1) · Athi Ponnusamy, MD (1) · Carly R Pacanowski, PhD RD (1) · Chonticha Kaewjoho, PT, PhD Kaewjoho (1) · Christine Skubisz, PhD (1) · Christos Iatrou, Medicine (1) · Eleni Chantzi, Medicine (1) · Gail Adler, MD, PhD (1) · George Basdekis, Medicine (1)
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I21RX001079 (1)