6 completed, 1 unknown. 7 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 6, Unknown 1 |
| Phase 2 | 2 | Completed 2 |
Follow Asphyxia Neonatorum: new trials by email Literature Review of Asphyxia Neonatorum trials Research Report on Asphyxia Neonatorum
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Finding Solutions to Thrive After Birth Asphyxia in Africa Sildenafil - Birth Asphyxia | Phase 1 | Completed | Pia Wintermark | 18 | 2022-07-01 | 2026-09-15 |
| Sildenafil to Repair Brain Injury Secondary to Birth Asphyxia Sildenafil Citrate - Birth Asphyxia | Phase 1 | Completed | McGill University Health Centre/Research Institute of the McGill University Health Centre | 20 | 2019-09-19 | 2026-09-15 |
| Feasibility and Safety of Umbilical Cord Blood Transfusion in the Treatment of Neonatal Cerebral Ischemia and Anemia autologous umbilical cord blood (UCB), standard care - Hypoxic-Ischemic Encephalopathy, Hypoxia Neonatal | Phase 1 | Unknown | Mononuclear Therapeutics Ltd. | 40 | 2018-04-16 | 2018-06-07 |
| Sildenafil Administration to Treat Neonatal Encephalopathy Sildenafil, Ora-Blend - Neonatal Encephalopathy | Phase 1 | Completed | McGill University Health Centre/Research Institute of the McGill University Health Centre | 28 | 2016-07-01 | 2022-02-08 |
| Neonatal Erythropoietin And Therapeutic Hypothermia Outcomes in Newborn Brain Injury (NEATO) Erythropoietin, Normal saline - Hypoxic-ischemic Encephalopathy, Neonatal Encephalopathy | Phase 1 / Phase 2 | Completed | University of California, San Francisco | 50 | 2013-09-01 | 2020-07-13 |
| Neonatal Erythropoietin in Asphyxiated Term Newborns erythropoietin - Hypoxic-ischemic Encephalopathy | Phase 1 | Completed | University of California, San Francisco | 24 | 2010-01-01 | 2012-11-09 |
| Erythropoietin in Infants With Hypoxic Ischemic Encephalopathy (HIE) Human recombinant erythropoietin, EEG and Brain MRI, Nitric oxide measurement in the blood - Hypoxic Ischemic Encephalopathy | Phase 1 / Phase 2 | Completed | Tanta University | 45 | 2007-10-01 | 2009-09-28 |
Hypoxia-Ischemia, Brain (5) · Anemia, Neonatal (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (7) · Infant, Newborn, Diseases (7) · Brain Diseases (5) · Brain Ischemia (5) · Cardiovascular Diseases (5) · Central Nervous System Diseases (5) · Cerebrovascular Disorders (5) · Hypoxia (5) · Hypoxia, Brain (5) · Nervous System Diseases (5) · Pathological Conditions, Signs and Symptoms (5) · Signs and Symptoms (5) · Signs and Symptoms, Respiratory (5) · Vascular Diseases (5) · Anemia (1)
Sildenafil Citrate (3) · Epoetin Alfa (2) · Erythropoietin (2) · Endothelium-Dependent Relaxing Factors (1) · Saline Solution (1) · Standard of Care (1)
McGill University Health Centre/Research Institute of the McGill University Health Centre (2) · University of California, San Francisco (2) · Mononuclear Therapeutics Ltd. (1) · Pia Wintermark (1) · Tanta University (1)
Canada (2) · United States (2) · Egypt (1) · Hong Kong (1) · Uganda (1)
Yvonne W Wu, MD, MPH (2) · Pia Wintermark, Pia (1) · Simon Lam, MD (1)
PMID 20385632, PMID 23008465, PMID 24524452, PMID 25439577, PMID 30661082, PMID 31261373, PMID 37199820, PMID 38142044, PMID 40562301